DE FRANCO, MICHELE
DE FRANCO, MICHELE
Dipartimento di Scienze del Farmaco - DSF
1,2,4-Amino-triazine derivatives as pyruvate dehydrogenase kinase inhibitors: Synthesis and pharmacological evaluation
2023 Pecoraro, Camilla; DE FRANCO, Michele; Carbone, Daniela; Bassani, Davide; Pavan, Matteo; Cascioferro, Stella; Parrino, Barbara; Cirrincione, Girolamo; Dall'Acqua, Stefano; Moro, Stefano; Gandin, Valentina; Diana, Patrizia
1,3,5-Triaza-7-phosphaadamantane and Cyclohexyl Groups Impart to Di-Iron(I) Complex Aqueous Solubility and Stability, and Prominent Anticancer Activity in Cellular and Animal Models
2024 De Franco, M.; Biancalana, L.; Zappelli, C.; Zacchini, S.; Gandin, V.; Marchetti, F.
Anticancer activity of new water-soluble sulfonated thiosemicarbazone copper(II) complexes targeting disulfide isomerase
2024 Miglioli, F.; De Franco, M.; Bartoli, J.; Scaccaglia, M.; Pelosi, G.; Marzano, C.; Rogolino, D.; Gandin, V.; Carcelli, M.
Anticancer activity, DNA binding and cell mechanistic studies of estrogen-functionalised Cu(II) complexes
2020 Barrett, S.; De Franco, M.; Kellett, A.; Dempsey, E.; Marzano, C.; Erxleben, A.; Gandin, V.; Montagner, D.
Antiproliferative Homoleptic and Heteroleptic Phosphino Silver(I) Complexes: Effect of Ligand Combination on Their Biological Mechanism of Action
2020 Dammak, K.; Porchia, M.; De Franco, M.; Zancato, M.; Naili, H.; Gandin, V.; Marzano, C.
Appended Aromatic Moieties in Flexible Bis‐3‐chloropiperidines Confer Tropism against Pancreatic Cancer Cells
2021 Carraro, Caterina; Helbing, Tim; Francke, Alexander; Zuravka, Ivonne; Sosic, Alice; De Franco, Michele; Gandin, Valentina; Gatto, Barbara; Göttlich, D. Richard
Aromatic Linkers Unleash the Antiproliferative Potential of 3-Chloropiperidines Against Pancreatic Cancer Cells
2020 Helbing, Tim; Carraro, Caterina; Francke, Alexander; Sosic, Alice; De Franco, Michele; Gandin, Valentina; Göttlich, Richard; Gatto, Barbara
Behind the Mirror: Chirality Tunes the Reactivity and Cytotoxicity of Chloropiperidines as Potential Anticancer Agents
2019 Carraro, Caterina; Francke, Alexander; Sosic, Alice; Kohl, Franziska; Helbing, Tim; De Franco, Michele; Fabris, Daniele; Göttlich, Richard; Gatto, Barbara
Cu(I) and Cu(II) Complexes Based on Lonidamine-Conjugated Ligands Designed to Promote Synergistic Antitumor Effects
2022 Del Bello, Fabio; Pellei, Maura; Bagnarelli, Luca; Santini, Carlo; Giorgioni, Gianfabio; Piergentili, Alessandro; Quaglia, Wilma; Battocchio, Chiara; Iucci, Giovanna; Schiesaro, Irene; Meneghini, Carlo; Venditti, Iole; Ramanan, Nitya; De Franco, Michele; Sgarbossa, Paolo; Marzano, Cristina; Gandin, Valentina
Decoding mechanism of action and sensitivity to drug candidates from integrated transcriptome and chromatin state
2022 Carraro, Caterina; Bonaguro, Lorenzo; Schulte-Schrepping, Jonas; Horne, Arik; Oestreich, Marie; Warnat-Herresthal, Stefanie; Helbing, Tim; De Franco, Michele; Haendler, Kristian; Mukherjee, Sach; Ulas, Thomas; Gandin, Valentina; Goettlich, Richard; Aschenbrenner, Anna C; Schultze, Joachim L; Gatto, Barbara
DEVELOPMENT OF TARGET-SPECIFIC AND TUMOR-SELECTIVE METALLODRUGS
2024 DE FRANCO, Michele
Discovery of the 3-Amino-1,2,4-triazine-Based Library as Selective PDK1 Inhibitors with Therapeutic Potential in Highly Aggressive Pancreatic Ductal Adenocarcinoma
2023 Carbone, Daniela; DE FRANCO, Michele; Pecoraro, Camilla; Bassani, Davide; Pavan, Matteo; Cascioferro, Stella; Parrino, Barbara; Cirrincione, Girolamo; Dall’Acqua, Stefano; Moro, Stefano; Gandin, Valentina; Diana, Patrizia
Easily Available, Amphiphilic Diiron Cyclopentadienyl Complexes Exhibit in Vitro Anticancer Activity in 2D and 3D Human Cancer Cells through Redox Modulation Triggered by CO Release
2021 Biancalana, L.; De Franco, M.; Ciancaleoni, G.; Zacchini, S.; Pampaloni, G.; Gandin, V.; Marchetti, F.
Exploring the Antitumor Potential of Copper Complexes Based on Ester Derivatives of Bis(pyrazol-1-yl)acetate Ligands
2022 Pellei, Maura; Santini, Carlo; Bagnarelli, Luca; Battocchio, Chiara; Iucci, Giovanna; Venditti, Iole; Meneghini, Carlo; Amatori, Simone; Sgarbossa, Paolo; Marzano, Cristina; De Franco, Michele; Gandin, Valentina
Himalayan Nettle Girardinia diversifolia as a Candidate Ingredient for Pharmaceutical and Nutraceutical Applications-Phytochemical Analysis and In Vitro Bioassays
2020 Sharan Shrestha, Shyam; Sut, Stefania; Ferrarese, Irene; Barbon Di Marco, Serena; Zengin, Gokhan; De Franco, Michele; Pant, Deepak Raj; Mahomoodally, Mohamad Fawzi; Ferri, Nicola; Biancorosso, Noemi; Maggi, Filippo; Dall Acqua, Stefano; Rajbhandary, Sangeeta
Insight on pyrimido[5,4-g]indolizine and pyrimido[4,5-c]pyrrolo[1,2-a]azepine systems as promising photosensitizers on malignant cells
2022 Barreca, M; Ingarra, Am; Raimondi, Mv; Spanò, V; De Franco, M; Menilli, L; Gandin, V; Miolo, G; Barraja, P; Montalbano, A.
New tricyclic systems as photosensitizers towards triple negative breast cancer cells
2022 Barreca, Marilia; Ingarra, Angela Maria; Raimondi, Maria Valeria; Spanò, Virginia; Piccionello, Antonio Palumbo; De Franco, Michele; Menilli, Luca; Gandin, Valentina; Miolo, Giorgia; Barraja, Paola; Montalbano, Alessandra
Novel Biotinylated Cu(II)-Phenanthroline Complexes: 2D and 3D Cytotoxic Activity and Mechanistic Insight
2023 Barrett, Stephen; De Franco, Michele; Donati, Chiara; Marzano, Cristina; Gandin, Valentina; Montagner, Diego
Novel Silver Complexes Based on Phosphanes and Ester Derivatives of Bis(pyrazol-1-yl)acetate Ligands Targeting TrxR: New Promising Chemotherapeutic Tools Relevant to SCLC Management
2023 Pellei, Maura; Santini, Carlo; Bagnarelli, Luca; Caviglia, Miriam; Sgarbossa, Paolo; De Franco, Michele; Zancato, Mirella; Marzano, Cristina; Gandin, Valentina
Phytochemical fingerprinting and in vitro bioassays of the ethnomedicinal fern tectaria coadunata (J. Smith) C. Christensen from Central Nepal
2019 Shrestha, S. S.; Sut, S.; Di Marco, S. B.; Zengin, G.; Gandin, V.; De Franco, M.; Pant, D. R.; Mahomoodally, M. F.; Dall'Acqua, S.; Rajbhandary, S.