GATTO, BARBARA
GATTO, BARBARA
Dipartimento di Scienze del Farmaco - DSF
Allostery in homodimeric SARS-CoV-2 main protease
2024 Fornasier, Emanuele; Fabbian, Simone; Shehi, Haidi; Enderle, Janine; Gatto, Barbara; Volpin, Daniele; Biondi, Barbara; Bellanda, Massimo; Giachin, Gabriele; Sosic, Alice; Battistutta, Roberto
Secondary 3‐Chloropiperidines: Powerful Alkylating Agents
2024 Georg, Mats; Laping, Lina Alexandra; Billo, Veronica; Gatto, Barbara; Friedhoff, Peter; Göttlich, Richard
In Vitro Chemical Mapping of G-Quadruplex DNA Structures by Bis-3-Chloropiperidines
2023 Sosic, Alice; Dal Lago, Cristina; Goettlich, Richard; Gatto, Barbara
A new inactive conformation of SARS-CoV-2 main protease
2022 Fornasier, Emanuele; Macchia, Maria Ludovica; Giachin, Gabriele; Sosic, Alice; Pavan, Matteo; Sturlese, Mattia; Salata, Cristiano; Moro, Stefano; Gatto, Barbara; Bellanda, Massimo; Battistutta, Roberto
Computationally driven discovery of SARS-CoV-2 Mpro inhibitors: from design to experimental validation
2022 El Khoury, Léa; Jing, Zhifeng; Cuzzolin, Alberto; Deplano, Alessandro; Loco, Daniele; Sattarov, Boris; Hédin, Florent; Wendeborn, Sebastian; Ho, Chris; El Ahdab, Dina; Jaffrelot-Inizan, Theo; Sturlese, M; Sosic, Alice; Volpiana, Martina; Lugato, Angela; Barone, Marco; Gatto, Barbara; Macchia, Maria Ludovica.; Bellanda, M; Battistutta, Roberto; Salata, Cristiano; Kondratov, Ivan; Iminov, Rustan; Khairulin, Andrii; Mykhalonok, Yaroslav; Pochepko, Anton; Chashka-Ratushnyi, Volodymyr; Kos, Iaroslava; Moro, Stefano; Montes, Matthieu; Ren, Pengyu; Ponder, Jay W.; Lagardère, Louis; Piquemal, Jean-Philip; Sabbadin, Davide
Decoding mechanism of action and sensitivity to drug candidates from integrated transcriptome and chromatin state
2022 Carraro, Caterina; Bonaguro, Lorenzo; Schulte-Schrepping, Jonas; Horne, Arik; Oestreich, Marie; Warnat-Herresthal, Stefanie; Helbing, Tim; De Franco, Michele; Haendler, Kristian; Mukherjee, Sach; Ulas, Thomas; Gandin, Valentina; Goettlich, Richard; Aschenbrenner, Anna C; Schultze, Joachim L; Gatto, Barbara
IDENTIFICATION OF NEW SARS-COV-2 MAIN PROTEASE INHIBITORS BY AN INTEGRATED IN-SILICO AND IN-VITRO STRATEGY
2022 Salata, C.; Mirandola, M.; Salaris, C.; Macchia, M. L.; Fornasier, E.; Pavan, M.; Giachin, G.; Sosic, A.; Sturlese, M.; Bellanda, M.; Battistutta, R.; Moro, S.; Gatto, B.
In Vitro Evaluation of Bis-3-Chloropiperidines as RNA Modulators Targeting TAR and TAR-Protein Interaction
2022 Sosic, A.; Olivato, G.; Carraro, C.; Gottlich, R.; Fabris, D.; Gatto, B.
Multifaceted Aspects of HIV-1 Nucleocapsid Inhibition by TAR-Targeting Peptidyl-Anthraquinones Bearing Terminal Aromatic Moieties
2022 Sosic, Alice; Frecentese, Francesco; Olivato, Giulia; Rollo, Daniele; Carraro, Caterina; Gamba, Elia; Santagada, Vincenzo; Gatto, Barbara
Appended Aromatic Moieties in Flexible Bis‐3‐chloropiperidines Confer Tropism against Pancreatic Cancer Cells
2021 Carraro, Caterina; Helbing, Tim; Francke, Alexander; Zuravka, Ivonne; Sosic, Alice; De Franco, Michele; Gandin, Valentina; Gatto, Barbara; Göttlich, D. Richard
B-CePs as cross-linking probes for the investigation of RNA higher-order structure
2021 Sosic, Alice; Göttlich, Richard; Fabris, Dan; Gatto, Barbara
Bis-3-Chloropiperidines Targeting TAR RNA as A Novel Strategy to Impair the HIV-1 Nucleocapsid Protein
2021 Sosic, Alice; Olivato, Giulia; Carraro, Caterina; Göttlich, Richard; Fabris, Dan; Gatto, Barbara
DNA-Binding Properties of Cytotoxic Naphtindolizinedione-Carboxamides Acting as Type II Topoisomerase Inhibitors. A Combined In Silico and Experimental Study
2021 Defant, Andrea; Gatti, Paolo; Poli, Alessandro; Serena, Marta; Sosic, Alice; Gatto, Barbara; Mancini, Ines
Understanding the Alkylation Mechanism of 3‐Chloropiperidines – NMR Kinetic Studies and Isolation of Bicyclic Aziridinium Ions
2021 Helbing, Tim; Georg, Mats; Stöhr, Fabian; Carraro, Caterina; Becker, Jonathan; Gatto, Barbara; Göttlich, Richard
Aromatic Linkers Unleash the Antiproliferative Potential of 3-Chloropiperidines Against Pancreatic Cancer Cells
2020 Helbing, Tim; Carraro, Caterina; Francke, Alexander; Sosic, Alice; De Franco, Michele; Gandin, Valentina; Göttlich, Richard; Gatto, Barbara
Multiple in Vitro Inhibition of HIV-1 Proteins by 2,6-Dipeptidyl-anthraquinone Conjugates Targeting the PBS RNA
2020 Gamba, Elia; Sosic, Alice; Saccone, Irene; Magli, Elisa; Frecentese, Francesco; Gatto, Barbara
Behind the Mirror: Chirality Tunes the Reactivity and Cytotoxicity of Chloropiperidines as Potential Anticancer Agents
2019 Carraro, Caterina; Francke, Alexander; Sosic, Alice; Kohl, Franziska; Helbing, Tim; De Franco, Michele; Fabris, Daniele; Göttlich, Richard; Gatto, Barbara
Design and synthesis of wm5 analogues as HIV-1 TAR RNA binders
2019 Desantis, J.; Massari, S.; Sosic, A.; Manfroni, G.; Cannalire, R.; Felicetti, T.; Pannecouque, C.; Gatto, B.; Tabarrini, O.
A New Beautiful Friendship: Solution Thermal Melting and Nanospray-MS for the Characterization of Intermolecular Conjugates Produced by Bifunctional Crosslinking
2018 Sosic, Alice; Botros, Toro; Goettlich, Richard; Pan T. X., Li; Gatto, Barbara; Dan, Fabris
Identification of novel 2-benzoxazolinone derivatives with specific inhibitory activity against the HIV-1 nucleocapsid protein
2018 Gamba, Elia; Mori, Mattia; Kovalenko, Lesia; Giannini, Alessia; Sosic, Alice; Saladini, Francesco; Fabris, Dan; Mely, YVES CAMILLE RENE'; Gatto, Barbara; Botta, Maurizio