TOSATTO, SILVIO
TOSATTO, SILVIO
Dipartimento di Scienze Biomediche - DSB
CAGI6 ID panel challenge: assessment of phenotype and variant predictions in 415 children with neurodevelopmental disorders (NDDs)
2025 Aspromonte, Maria Cristina; Del Conte, Alessio; Zhu, Shaowen; Tan, Wuwei; Shen, Yang; Zhang, Yexian; Li, Qi; Wang, Maggie Haitian; Babbi, Giulia; Bovo, Samuele; Martelli, Pier Luigi; Casadio, Rita; Althagafi, Azza; Toonsi, Sumyyah; Kulmanov, Maxat; Hoehndorf, Robert; Katsonis, Panagiotis; Williams, Amanda; Lichtarge, Olivier; Xian, Su; Surento, Wesley; Pejaver, Vikas; Mooney, Sean D.; Sunderam, Uma; Srinivasan, Rajgopal; Murgia, Alessandra; Piovesan, Damiano; Tosatto, Silvio C. E.; Leonardi, Emanuela
Critical Assessment of Protein Intrinsic Disorder Round 3 ‐ Predicting Disorder in the Era of Protein Language Models
2025 Mehdiabadi, Mahta; Del Conte, Alessio; Nugnes, Maria Victoria; Aspromonte, Maria Cristina; Tosatto, Silvio C. E.; Piovesan, Damiano
Decoding protein structures with residue interaction networks
2025 Begue, S. C.; Leonardi, E.; Tosatto, S. C. E.
DRMAAtic: dramatically improve your cluster potential
2025 Del Conte, Alessio; Ghafouri, Hamidreza; Clementel, Damiano; Mičetić, Ivan; Piovesan, Damiano; Tosatto, Silvio C E; Monzon, Alexander Miguel
Genetic variants and phenotypic data curated for the CAGI6 intellectual disability panel challenge
2025 Aspromonte, Maria Cristina; Del Conte, Alessio; Polli, Roberta; Baldo, Demetrio; Benedicenti, Francesco; Bettella, Elisa; Bigoni, Stefania; Boni, Stefania; Ciaccio, Claudia; D'Arrigo, Stefano; Donati, Ilaria; Granocchio, Elisa; Mammi, Isabella; Milani, Donatella; Negrin, Susanna; Nosadini, Margherita; Soli, Fiorenza; Stanzial, Franco; Turolla, Licia; Piovesan, Damiano; Tosatto, Silvio C E; Murgia, Alessandra; Leonardi, Emanuela
GeomeTRe: accurate calculation of geometrical descriptors of tandem repeat proteins
2025 Osmanli, Zarifa; Ferrero, Elisa; Monzon, Alexander Miguel; Tosatto, Silvio C E; Piovesan, Damiano
InterPro: The protein sequence classification resource in 2025
2025 Blum, M.; Andreeva, A.; Florentino, L. C.; Chuguransky, S. R.; Grego, T.; Hobbs, E.; Pinto, B. L.; Orr, A.; Paysan-Lafosse, T.; Ponamareva, I.; Salazar, G. A.; Bordin, N.; Bork, P.; Bridge, A.; Colwell, L.; Gough, J.; Haft, D. H.; Letunic, I.; Llinares-Lopez, F.; Marchler-Bauer, A.; Meng-Papaxanthos, L.; Mi, H.; Natale, D. A.; Orengo, C. A.; Pandurangan, A. P.; Piovesan, D.; Rivoire, C.; Sigrist, C. J. A.; Thanki, N.; Thibaud-Nissen, F.; Thomas, P. D.; Tosatto, S. C. E.; Wu, C. H.; Bateman, A.
MobiDB-lite 4.0: faster prediction of intrinsic protein disorder and structural compactness
2025 Mehdiabadi, Mahta; Blum, Matthias; Tesei, Giulio; Von Bülow, Sören; Lindorff-Larsen, Kresten; Tosatto, Silvio C E; Piovesan, Damiano
The Pfam protein families database: Embracing AI/ML
2025 Paysan-Lafosse, T.; Andreeva, A.; Blum, M.; Chuguransky, S. R.; Grego, T.; Pinto, B. L.; Salazar, G. A.; Bileschi, M. L.; Llinares-Lopez, F.; Meng-Papaxanthos, L.; Colwell, L. J.; Grishin, N. V.; Schaeffer, R. D.; Clementel, D.; Tosatto, S. C. E.; Sonnhammer, E.; Wood, V.; Bateman, A.
A PDZ scaffolding/CaM-mediated pathway in Cryptochrome signaling
2024 Bellanda, M.; Damulewicz, M.; Zambelli, B.; Costanzi, E.; Gregoris, F.; Mammi, S.; Tosatto, S. C. E.; Costa, R.; Minervini, G.; Mazzotta, G. M.
Best practices for the manual curation of intrinsically disordered proteins in DisProt
2024 Quaglia, Federica; Chasapi, Anastasia; Nugnes, Maria Victoria; Aspromonte, Maria Cristina; Leonardi, Emanuela; Piovesan, Damiano; Tosatto, Silvio C E
CAFA-evaluator: a Python tool for benchmarking ontological classification methods
2024 Piovesan, Damiano; Zago, Davide; Joshi, Parnal; De Paolis Kaluza, M Clara; Mehdiabadi, Mahta; Ramola, Rashika; Monzon, Alexander Miguel; Reade, Walter; Friedberg, Iddo; Radivojac, Predrag; Tosatto, Silvio C E
CAGI, the Critical Assessment of Genome Interpretation, establishes progress and prospects for computational genetic variant interpretation methods
2024 Jain, Shantanu; Bakolitsa, Constantina; E Brenner, Steven; Radivojac, Predrag; Moult, John; Repo, Susanna; A Hoskins, Roger; Andreoletti, Gaia; Barsky, Daniel; Chellapan, Ajithavalli; Chu, Hoyin; Dabbiru, Navya; K Kollipara, Naveen; Ly, Melissa; J Neumann, Andrew; R Pal, Lipika; Odell, Eric; Pandey, Gaurav; C Peters-Petrulewicz, Robin; Srinivasan, Rajgopal; F Yee, Stephen; Jyothsna Yeleswarapu, Sri; Zuhl, Maya; Adebali, Ogun; Patra, Ayoti; A Beer, Michael; Hosur, Raghavendra; Peng, Jian; M Bernard, Brady; Berry, Michael; Dong, Shengcheng; P Boyle, Alan; Adhikari, Aashish; Chen, Jingqi; Hu, Zhiqiang; Wang, Robert; Wang, Yaqiong; Miller, Maximilian; Wang, Yanran; Bromberg, Yana; Turina, Paola; Capriotti, Emidio; J Han, James; Ozturk, Kivilcim; Carter, Hannah; Babbi, Giulia; Bovo, Samuele; Di Lena, Pietro; Luigi Martelli, Pier; Savojardo, Castrense; Casadio, Rita; S Cline, Melissa; De Baets, Greet; Bonache, Sandra; Díez, Orland; Gutiérrez-Enríquez, Sara; Fernández, Alejandro; Montalban, Gemma; Ootes, Lars; Özkan, Selen; Padilla, Natàlia; Riera, Casandra; De la Cruz, Xavier; Diekhans, Mark; J Huwe, Peter; Wei, Qiong; Xu, Qifang; L Dunbrack, Roland; Gotea, Valer; Elnitski, Laura; Margolin, Gennady; Fariselli, Piero; V Kulakovskiy, Ivan; J Makeev, Vsevolod; D Penzar, Dmitry; E Vorontsov, Ilya; V Favorov, Alexander; R Forman, Julia; Hasenahuer, Marcia; S Fornasari, Maria; Parisi, Gustavo; Avsec, Ziga; H Çelik, Muhammed; Yen Duong Nguyen, Thi; Gagneur, Julien; Shi, Fang-Yuan; D Edwards, Matthew; Guo, Yuchun; Tian, Kevin; Zeng, Haoyang; K Gifford, David; Göke, Jonathan; Zaucha, Jan; Gough, Julian; S Ritchie, Graham R; Frankish, Adam; M Mudge, Jonathan; Harrow, Jennifer; L Young, Erin; Yu, Yao; D Huff, Chad; Murakami, Katsuhiko; Nagai, Yoko; Imanishi, Tadashi; J Mungall, Christopher; B Jacobsen, Julius O; Kim, Dongsup; Jeong, Chan-Seok; T Jones, David; Jun Li, Mulin; Beleva Guthrie, Violeta; Bhattacharya, Rohit; Chen, Yun-Ching; Douville, Christopher; Fan, Jean; Kim, Dewey; Masica, David; Niknafs, Noushin; Sengupta, Sohini; Tokheim, Collin; N Turner, Tychele; Ting Grace Yeo, Hui; Karchin, Rachel; Shin, Sunyoung; Welch, Rene; Keles, Sunduz; Li, Yue; Kellis, Manolis; Corbi-Verge, Carles; V Strokach, Alexey; M Kim, Philip; E Klein, Teri; Mohan, Rahul; A Sinnott-Armstrong, Nicholas; Wainberg, Michael; Kundaje, Anshul; Gonzaludo, Nina; Y Mak, Angel C; Chhibber, Aparna; K Lam, Hugo Y; Dahary, Dvir; Fishilevich, Simon; Lancet, Doron; Lee, Insuk; Bachman, Benjamin; Katsonis, Panagiotis; C Lua, Rhonald; J Wilson, Stephen; Lichtarge, Olivier; R Bhat, Rajendra; Sundaram, Laksshman; Viswanath, Vivek; Bellazzi, Riccardo; Nicora, Giovanna; Rizzo, Ettore; Limongelli, Ivan; M Mezlini, Aziz; Chang, Ray; Kim, Serra; Lai, Carmen; O'Connor, Robert; Topper, Scott; van den Akker, Jeroen; Y Zhou, Alicia; D Zimmer, Anjali; Mishne, Gilad; R Bergquist, Timothy; R Breese, Marcus; F Guerrero, Rafael; Jiang, Yuxiang; Kiga, Nikki; Li, Biao; Mort, Matthew; A Pagel, Kymberleigh; Pejaver, Vikas; H Stamboulian, Moses; Thusberg, Janita; D Mooney, Sean; Teerakulkittipong, Nuttinee; Cao, Chen; Kundu, Kunal; Yin, Yizhou; Yu, Chen-Hsin; Kleyman, Michael; Lin, Chiao-Feng; Stackpole, Mary; M Mount, Stephen; Eraslan, Gökcen; S Mueller, Nikola; Naito, Tatsuhiko; R Rao, Aliz; R Azaria, Johnathan; Brodie, Aharon; Ofran, Yanay; Garg, Aditi; Pal, Debnath; Hawkins-Hooker, Alex; Kenlay, Henry; Reid, John; J Mucaki, Eliseos; K Rogan, Peter; M Schwarz, Jana; B Searls, David; Rie Lee, Gyu; Seok, Chaok; Krämer, Andreas; Shah, Sohela; V Huang, Chenglai; F Kirsch, Jack; Shatsky, Maxim; Cao, Yue; Chen, Haoran; Karimi, Mostafa; Moronfoye, Oluwaseyi; Sun, Yuanfei; Shen, Yang; Shigeta, Ron; T Ford, Colby; Nodzak, Conor; Uppal, Aneeta; Shi, Xinghua; Joseph, Thomas; Kotte, Sujatha; Rana, Sadhna; Rao, Aditya; G Saipradeep, V; Sivadasan, Naveen; Sunderam, Uma; Stanke, Mario; Su, Andrew; Adzhubey, Ivan; M Jordan, Daniel; Sunyaev, Shamil; Rousseau, Frederic; Schymkowitz, Joost; Van Durme, Joost; V Tavtigian, Sean; Carraro, Marco; Giollo, Manuel; Tosatto, Silvio; Adato, Orit; Carmel, Liran; E Cohen, Noa; Fenesh, Tzila; Holtzer, Tamar; Juven-Gershon, Tamar; Unger, Ron; Niroula, Abhishek; Olatubosun, Ayodeji; Väliaho, Jouni; Yang, Yang; Vihinen, Mauno; E Wahl, Mary; Chang, Billy; Chun Chong, Ka; Hu, Inchi; Sun, Rui; Ka Kei Wu, William; Xia, Xiaoxuan; C Zee, Benny; H Wang, Maggie; Wang, Meng; Wu, Chunlei; Lu, Yutong; Chen, Ken; Yang, Yuedong; M Yates, Christopher; Kreimer, Anat; Yan, Zhongxia; Yosef, Nir; Zhao, Huying; Wei, Zhipeng; Yao, Zhaomin; Zhou, Fengfeng; Folkman, Lukas; Zhou, Yaoqi; Daneshjou, Roxana; B Altman, Russ; Inoue, Fumitaka; Ahituv, Nadav; P Arkin, Adam; Lovisa, Federica; Bonvini, Paolo; Bowdin, Sarah; Gianni, Stefano; Mantuano, Elide; Minicozzi, Velia; Novak, Leonore; Pasquo, Alessandra; Pastore, Annalisa; Petrosino, Maria; Puglisi, Rita; Toto, Angelo; Veneziano, Liana; Chiaraluce, Roberta; P Ball, Mad; R Bobe, Jason; M Church, George; Consalvi, Valerio; N Cooper, David; A Buckley, Bethany; B Sheridan, Molly; R Cutting, Garry; Chiara Scaini, Maria; J Cygan, Kamil; M Fredericks, Alger; T Glidden, David; Neil, Christopher; L Rhine, Christy; G Fairbrother, William; Y Alontaga, Aileen; W Fenton, Aron; A Matreyek, Kenneth; M Starita, Lea; M Fowler, Douglas; Löscher, Britt-Sabina; Franke, Andre; I Adamson, Scott; R Graveley, Brenton; W Gray, Joe; J Malloy, Mary; P Kane, John; Kousi, Maria; Katsanis, Nicholas; Schubach, Max; Kircher, Martin; Y Mak, Angel C; F Tang, Paul L; Kwok, Pui-Yan; H Lathrop, Richard; T Clark, Wyatt; K Yu, Guoying; H LeBowitz, Jonathan; Benedicenti, Francesco; Bettella, Elisa; Bigoni, Stefania; Cesca, Federica; Mammi, Isabella; Marino-Buslje, Cristina; Milani, Donatella; Peron, Angela; Polli, Roberta; Sartori, Stefano; Stanzial, Franco; Toldo, Irene; Turolla, Licia; C Aspromonte, Maria; Bellini, Mariagrazia; Leonardi, Emanuela; Liu, Xiaoming; Marshall, Christian; Richard McCombie, W; Elefanti, Lisa; Menin, Chiara; Stephen Meyn, M; Murgia, Alessandra; Y Nadeau, Kari C; L Neuhausen, Susan; L Nussbaum, Robert; Pirooznia, Mehdi; B Potash, James; F Dimster-Denk, Dago; D Rine, Jasper; R Sanford, Jeremy; Snyder, Michael; G Cote, Atina; Sun, Song; W Verby, Marta; Weile, Jochen; P Roth, Frederick; Tewhey, Ryan; C Sabeti, Pardis; Campagna, Joan; M Refaat, Marwan; Wojciak, Julianne; Grubb, Soren; Schmitt, Nicole; Shendure, Jay; B Spurdle, Amanda; J Stavropoulos, Dimitri; A Walton, Nephi; P Zandi, Peter; Ziv, Elad; Burke, Wylie; Chen, Flavia; R Carr, Lawrence; Martinez, Selena; Paik, Jodi; Harris-Wai, Julie; Yarborough, Mark; M Fullerton, Stephanie; A Koenig, Barbara; Mcinnes, Gregory; Shigaki, Dustin; Chandonia, John-Marc; Furutsuki, Mabel; Kasak, Laura; Yu, Changhua; Chen, Rui; Friedberg, Iddo; A Getz, Gad; Cong, Qian; N Kinch, Lisa; Zhang, Jing; V Grishin, Nick; Voskanian, Alin; G Kann, Maricel; Tran, Elizabeth; M Ioannidis, Nilah; M Hunter, Jesse; Udani, Rupa; Cai, Binghuang; A Morgan, Alexander; Sokolov, Artem; M Stuart, Joshua; Minervini, Giovanni; Monzon, Alexander Miguel; Batzoglou, Serafim; J Butte, Atul; S Greenblatt, Marc; K Hart, Reece; Hernandez, Ryan; P Hubbard, Tim J; Kahn, Scott; O'Donnell-Luria, Anne; C Ng, Pauline; Shon, John; Veltman, Joris; M Zook, Justin
Diversity and structural‐functional insights of alpha‐solenoid proteins
2024 Arrías, Paula Nazarena; Osmanli, Zarifa; Peralta, Estefanía; Chinestrad, Patricio Manuel; Monzon, Alexander Miguel; Tosatto, Silvio C. E.
DOME Registry: implementing community-wide recommendations for reporting supervised machine learning in biology
2024 Attafi, Omar Abdelghani; Clementel, Damiano; Kyritsis, Konstantinos; Capriotti, Emidio; Farrell, Gavin; Fragkouli, Styliani-Christina; Castro, Leyla Jael; Hatos, András; Lenaerts, Tom; Mazurenko, Stanislav; Mozaffari, Soroush; Pradelli, Franco; Ruch, Patrick; Savojardo, Castrense; Turina, Paola; Zambelli, Federico; Piovesan, Damiano; Monzon, Alexander Miguel; Psomopoulos, Fotis; Tosatto, Silvio C E
In Silico Exploration of AHR-HIF Pathway Interplay: Implications for Therapeutic Targeting in ccRCC
2024 Gregoris, Francesco; Minervini, Giovanni; Tosatto, Silvio C. E.
MOBIDB in 2025: integrating ensemble properties and function annotations for intrinsically disordered proteins
2024 Piovesan, D.; Conte, A. D.; Mehdiabadi, M.; Aspromonte, M. C.; Blum, M.; Tesei, G.; von Bulow, S.; Lindorff-Larsen, K.; Tosatto, S. C. E.
RepeatsDB in 2025: expanding annotations of structured tandem repeats proteins on AlphaFoldDB
2024 Clementel, Damiano; Arrías, Paula Nazarena; Mozaffari, Soroush; Osmanli, Zarifa; Castro, Ximena Aixa; Ferrari, Carlo; Kajava, Andrey V; Tosatto, Silvio C E; Monzon, Alexander Miguel
RING 4.0: faster residue interaction networks with novel interaction types across over 35,000 different chemical structures
2024 Del , ; DEL CONTE, Alessio; Camagni, GIORGIA FRANCESCA; Clementel, Damiano; Minervini, Giovanni; Monzon, Alexander Miguel; Ferrari, Carlo; Piovesan, Damiano; Tosatto, Silvio
Searching and Using MobiDB Resource 6 to Explore Predictions and Annotations for Intrinsically Disordered Proteins
2024 Aspromonte, M. C.; Quaglia, F.; Monzon, A. M.; Clementel, D.; Del Conte, A.; Piovesan, D.; Tosatto, S. C. E.