SCORRANO, LUCA
SCORRANO, LUCA
Dipartimento di Biologia - DiBio
The metabolically dependent interactomes of the mitochondrial cristae-shaping protein Opa1 in cardiac pathophysiology
In corso di stampa Lambert, Jonathan; Maracani, Aurora; Santorelli, Lucia; Grumati, Paolo; Scorrano, Luca
OPA1 Deficiency Impairs NGF Signaling and Drives Sympathetic Neurodegeneration
2026 Ronfini, Marco; Prando, Valentina; Di Mauro, Vittoria; Dokshokova, Lolita; Lazzeri, Erika; Costantini, Irene; Alàn, Lukas; Riviere, Erwan Andre; Incensi, Alex; Olianti, Camilla; La Morgia, Chiara; Liguori, Rocco; Sacconi, Leonardo; Donadio, Vincenzo; Scorrano, Luca; Carelli, Valerio; Mongillo, Marco; Zaglia, Tania
A guide to characterizing the dynamic mitochondria–endoplasmic reticulum contact sites
2025 Diokmetzidou, A.; Scorrano, L.
Endoplasmic reticulum–mitochondria contacts are prime hotspots of phospholipid peroxidation driving ferroptosis
2025 Sassano, M. L.; Tyurina, Y. Y.; Diometzidou, A.; Vervoort, E.; Tyurin, V. A.; More, S.; La Rovere, R.; Giordano, F.; Bultynck, G.; Pavie, B.; Swinnen, J. V.; Bayir, H.; Kagan, V. E.; Scorrano, L.; Agostinis, P.
Endoplasmic reticulum–mitochondria contacts are prime hotspots of phospholipid peroxidation driving ferroptosis
2025 Sassano, Maria Livia; Tyurina, Yulia Y.; Diokmetzidou, Antigoni; Vervoort, Ellen; Tyurin, Vladimir A.; More, Sanket; La Rovere, Rita; Giordano, Francesca; Bultynck, Geert; Pavie, Benjamin; Swinnen, Johan V.; Bayir, Hülya; Kagan, Valerian E.; Scorrano, Luca; Agostinis, Patrizia
Increased mitochondrial fusion via systemic OPA1 overexpression promotes dyslipidemia and atherosclerosis in LDLR deficient mice
2025 Da Dalt, L.; Fantini, F.; Giancane, G.; Moregola, A.; Roda, S.; Svecla, M.; Pedretti, S.; Vingiani, G. B.; Sun, J.; Edsfeldt, A.; Goncalves, I.; Uboldi, P.; Donetti, E.; Baragetti, A.; Mitro, N.; Scorrano, L.; Norata, G. D.
Iron Lion ZIPion: ZIP13 Zips Iron to Heart Mitochondria
2025 Fan, Hualin; Scorrano, Luca
Key challenges and recommendations for defining organelle membrane contact sites
2025 Cali, Tito; Bayer, Emmanuelle M.; Eden, Emily R.; Hajnóczky, György; Kornmann, Benoit; Lackner, Laura; Liou, Jen; Reinisch, Karin; Rhee, Hyun-Woo; Rizzuto, Rosario; Scorrano, Luca; Brini, Marisa
Marigold and MitoCIAO, two searchable compendia to visualize and functionalize protein complexes during mitochondrial remodeling
2025 Rigoni, Giovanni; Calvo, Enrique; Glytsou, Christina; Carro-Alvarellos, Marta; Noguchi, Masafumi; Semenzato, Martina; Quirin, Charlotte; Caicci, Federico; Meneghetti, Natascia; Sturlese, Mattia; Ishihara, Takaya; Moro, Stefano; Rampazzo, Chiara; Ishihara, Naotada; Bezzo, Fabrizio; Salviati, Leonardo; Vazquez, Jesùs; Sales, Gabriele; Romualdi, Chiara; Antonio Enriquez, Jose; Scorrano, Luca; SORIANO GARCIA - CUERVA, Maria Eugenia
Metastatic breast cancer cells are selectively dependent on the mitochondrial cristae-shaping protein OPA1
2025 Diokmetzidou, A.; Maracani, A.; Pellattiero, A.; Cardenas-Rodriguez, M.; Riviere, E. A.; Scorrano, L.
Mitochondria–membranous organelle contacts at a glance
2025 Diokmetzidou, A.; Scorrano, L.
Opantimirs: A class of antagonizing microRNAs that upregulate Opa1 and improve mitochondrial and disuse myopathies
2025 Djalalvandi, Andre; Takeda, Keisuke; Grespi, Francesca; Fan, Hualin; Fonseca, Tiago Branco; Nogara, Leonardo; Sharifi, Saman; Barison, Carlotta; Semenzato, Martina; Omori, Akiko; Cerutti, Raffaele; Steffan, Davide; Tsansizi, Lorenza; Balmaceda, Valeria; Alan, Lukas; Bean, Camilla; Blaauw, Bert; Viscomi, Carlo; Scorrano, Luca
Remodeling of Mitochondria–Endoplasmic Reticulum Contact Sites Accompanies LUHMES Differentiation
2025 Norouzi Esfahani, E.; Knedlik, T.; Shin, S. H.; Magalhães Rebelo, A. P.; De Mario, A.; Vianello, C.; Persano, L.; Rampazzo, E.; Edomi, P.; Bean, C.; Brunetti, D.; Scorrano, L.; Greco, S.; Gerdol, M.; Giacomello, M.
Small molecule OPA1 inhibitors amplify cytochrome c release and reverse cancer cells resistance to Bcl-2 inhibitors
2025 Pellattiero, Anna; Quirin, Charlotte; Magrin, Federico; Sturlese, Mattia; Fracasso, Alberto; Biris, Nikolaos; Herkenne, Stéphanie; Cendron, Laura; Gavathiotis, Evripidis; Moro, Stefano; Mattarei, Andrea; Scorrano, Luca
Small-molecule OPA1 inhibitors reverse mitochondrial adaptations to overcome therapy resistance in acute myeloid leukemia
2025 La Vecchia, S.; Doshi, S.; Antonoglou, P.; Kundu, T.; Al Santli, W.; Avrampou, K.; Witkowski, M. T.; Pellattiero, A.; Magrin, F.; Ames, K.; Verma, A.; Gritsman, K.; Su, X.; Mattarei, A.; Aifantis, I.; Scorrano, L.; Glytsou, C.
A RalA between high-fat diet and mitochondrial shape
2024 Zambello, L.; Scorrano, L.
Activation of Ca2+ phosphatase Calcineurin regulates Parkin translocation to mitochondria and mitophagy in flies
2024 Marchesan, E.; Nardin, A.; Mauri, S.; Bernardo, G.; Chander, V.; Di Paola, S.; Chinellato, M.; von Stockum, S.; Chakraborty, J.; Herkenne, S.; Basso, V.; Schrepfer, E.; Marin, O.; Cendron, L.; Medina, D. L.; Scorrano, L.; Ziviani, E.
Glutamine sensing licenses cholesterol synthesis
2024 Garcia, Bruna Martins; Melchinger, Philipp; Medeiros, Tania; Hendrix, Sebastian; Prabhu, Kavan; Corrado, Mauro; Kingma, Jenina; Gorbatenko, Andrej; Deshwal, Soni; Veronese, Matteo; Scorrano, Luca; Pearce, Erika; Giavalisco, Patrick; Zelcer, Noam; Pernas, Lena
Sweetening mitochondria: Hexokinase shields mitochondria from fission when glucose is low
2024 Diokmetzidou, A.; Scorrano, L.
The interplay between mitochondrial dynamics and autophagy: From a key homeostatic mechanism to a driver of pathology
2024 Lacombe, A.; Scorrano, L.