RUGGIERO, EMANUELA
RUGGIERO, EMANUELA
Dipartimento di Medicina Molecolare - DMM
7-Oxo-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxamides as Selective CB 2 cannabinoid receptor ligands: Structural investigations around a novel class of full agonists
2012 Baraldi, P. G.; Saponaro, G.; Moorman, A. R.; Romagnoli, R.; Preti, D.; Baraldi, S.; Ruggiero, E.; Varani, K.; Targa, M.; Vincenzi, F.; Borea, P. A.; Aghazadeh Tabrizi, M.
A dynamic i-motif with a duplex stem-loop in the long terminal repeat promoter of the HIV-1 proviral genome modulates viral transcription
2019 Ruggiero, Emanuela; Lago, Sara; Šket, Primož; Nadai, Matteo; Frasson, Ilaria; Plavec, Janez; Richter, Sara N
Antiviral Activity of the G-Quadruplex Ligand TMPyP4 against Herpes Simplex Virus-1
2021 Artusi, Sara; Ruggiero, Emanuela; Nadai, Matteo; Tosoni, Beatrice; Perrone, Rosalba; Ferino, Annalisa; Zanin, Irene; Xodo, Luigi; Flamand, Louis; Richter, Sara N
Discovery of 1,5-diphenylpyrazole-3-carboxamide derivatives as potent, reversible, and selective monoacylglycerol lipase (MAGL) inhibitors
2018 Aghazadeh Tabrizi, Mojgan; Giovanni Baraldi, Pier; Baraldi, Stefania; Ruggiero, Emanuela; De Stefano, Lucia; Rizzolio, Flavio; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; Chicca, Andrea; Lapillo, Margherita; Gertsch, Jürg; Manera, Clementina; Macchia, Marco; Martinelli, Adriano; Granchi, Carlotta; Minutolo, Filippo; Tuccinardi, Tiziano
Discovery of 7-oxopyrazolo[1,5-a]pyrimidine-6-carboxamides as potent and selective CB2 cannabinoid receptor inverse agonists
2013 Aghazadeh Tabrizi, M.; Baraldi, P. G.; Saponaro, G.; Moorman, A. R.; Romagnoli, R.; Preti, D.; Baraldi, S.; Ruggiero, E.; Tintori, C.; Tuccinardi, T.; Vincenzi, F.; Borea, P. A.; Varani, K.
Fused in Liposarcoma Protein, a New Player in the Regulation of HIV-1 Transcription, Binds to Known and Newly Identified LTR G-Quadruplexes
2022 Ruggiero, Emanuela; Frasson, Ilaria; Tosoni, Elena; Scalabrin, Matteo; Perrone, Rosalba; Marušič, Maja; Plavec, Janez; Richter, Sara
G-quadruplex targeting in the fight against viruses: An update
2021 Ruggiero, E.; Zanin, I.; Terreri, M.; Richter, S. N.
G-quadruplexes and G-quadruplex ligands: targets and tools in antiviral therapy
2018 Ruggiero, Emanuela; Richter, Sara N
G-Quadruplexes in Human Viruses: A Promising Route to Innovative Antiviral Therapies
2023 Ruggiero, E.; Richter, S. N.
Genome-wide mapping of i-motifs reveals their association with transcription regulation in live human cells
2023 Zanin, Irene; Ruggiero, Emanuela; Nicoletto, Giulia; Lago, Sara; Maurizio, Ilaria; Gallina, Irene; Richter, Sara N
Human Virus Genomes Are Enriched in Conserved Adenine/Thymine/Uracil Multiple Tracts That Pause Polymerase Progression
2022 Ruggiero, Emanuela; Lavezzo, Enrico; Grazioli, Marco; Zanin, Irene; Marušič, Maja; Plavec, Janez; Richter, Sara N; Toppo, Stefano
New synthesis of diazepino[3,2,1-ij]quinoline and pyrido[1,2,3-de] quinoxalines via addition-elimination followed by cycloacylation
2014 Baraldi, P. G.; Ruggiero, E.; Tabrizi, M. A.
One-Pot Reaction to Obtain N,N′-Disubstituted Guanidines of Pyrazolo[4,3- e ][1,2,4]triazolo[1,5- c ]pyrimidine Scaffold as Human A3 Adenosine Receptor Antagonists
2015 Baraldi, P. G.; Baraldi, S.; Saponaro, G.; Aghazadeh Tabrizi, M.; Romagnoli, R.; Ruggiero, E.; Vincenzi, F.; Borea, P. A.; Varani, K.
Pyrazole phenylcyclohexylcarbamates as inhibitors of human fatty acid amide hydrolases (FAAH)
2015 Aghazadeh Tabrizi, M.; Baraldi, P. G.; Ruggiero, E.; Saponaro, G.; Baraldi, S.; Romagnoli, R.; Martinelli, A.; Tuccinardi, T.
Stable and Conserved G-Quadruplexes in the Long Terminal Repeat Promoter of Retroviruses
2019 Ruggiero, Emanuela; Tassinari, Martina; Perrone, Rosalba; Nadai, Matteo; Richter, Sara N.
Synthesis and structure activity relationship investigation of triazolo[1,5-a]pyrimidines as CB2 cannabinoid receptor inverse agonists
2016 Aghazadeh Tabrizi, M.; Baraldi, P.; Ruggiero, E.; Saponaro, G.; Baraldi, S.; Poli, G.; Tuccinardi, T.; Ravani, A.; Vincenzi, F.; Borea, P.; Varani, K.
Targeting G-quadruplexes to achieve antiviral activity
2023 Ruggiero, Emanuela; Richter, Sara N
The cellular protein hnRNP A2/B1 enhances HIV-1 transcription by unfolding LTR promoter G-quadruplexes
2017 Scalabrin, Matteo; Frasson, Ilaria; Ruggiero, Emanuela; Perrone, Rosalba; Tosoni, Elena; Lago, Sara; Tassinari, Martina; Palu', Giorgio; Richter, Sara
The MDM2 inducible promoter folds into four-tetrad antiparallel G-quadruplexes targetable to fight malignant liposarcoma
2021 Lago, S.; Nadai, M.; Ruggiero, E.; Tassinari, M.; Marusic, M.; Tosoni, B.; Frasson, I.; Cernilogar, F. M.; Pirota, V.; Doria, F.; Plavec, J.; Schotta, G.; Richter, S. N.
Viral G-quadruplexes: New frontiers in virus pathogenesis and antiviral therapy
2020 Ruggiero, E.; Richter, S. N.