LAQUATRA, CLAUDIO
LAQUATRA, CLAUDIO
Dipartimento di Scienze Biomediche - DSB
New allosteric modulators of molecular chaperone TRAP1 from the integration of computational biology, medicinal chemistry, and biophysics
2026 Guarra, Federica; Komarov, Denis; Ciamarone, Andrea; Torielli, Luca; Previtali, Viola; Margaroli, Natasha; Romeo, Elisa; La Spina, Martina; Sbuelz, Francesca; Laquatra, Claudio; Veronesi, Marina; Lolicato, Marco; Arrigoni, Cristina; Moroni, Elisabetta; Serapian, Stefano A.; Girotto, Stefania; Rasola, Andrea; Colombo, Giorgio
TRAP1 ablation improves mitochondrial cristae and oxidative phosphorylation in pancreatic cancer stem cells
2026 Ambrosini, Giulia; Dalla Pozza, Elisa; Cristanini, Ilaria; Vinco, Sara; Cappellozza, Enrica; Cisterna, Barbara; Laquatra, Claudio; Rasola, Andrea; Bottani, Emanuela; Dando, Ilaria
Point mutations of the mitochondrial chaperone TRAP1 affect its functions and pro-neoplastic activity
2025 Laquatra, Claudio; Magro, Alessia; Guarra, Federica; Lambrughi, Matteo; Ferrone, Lavinia; Fracasso, Giulio; Bacchin, Melissa; La Spina, Martina; Moroni, Elisabetta; Papaleo, Elena; Colombo, Giorgio; Rasola, Andrea
Design and Test of Molecules that Interfere with the Recognition Mechanisms between the SARS-CoV-2 Spike Protein and Its Host Cell Receptors
2024 Scantamburlo, Francesca; Masgras, Ionica; Ciscato, Francesco; Laquatra, Claudio; Frigerio, Francesco; Cinquini, Fabrizio; Pavoni, Silvia; Triveri, Alice; Frasnetti, Elena; Serapian, Stefano A.; Colombo, Giorgio; Rasola, Andrea; Moroni, Elisabetta
STAT3 and HIF1α cooperatively mediate the transcriptional and physiological responses to hypoxia
2023 Dinarello, Alberto; Betto, Riccardo Massimiliano; Diamante, Linda; Tesoriere, Annachiara; Ghirardo, Rachele; Cioccarelli, Chiara; Meneghetti, Giacomo; Peron, Margherita; Laquatra, Claudio; Tiso, Natascia; Martello, Graziano; Argenton, Francesco
Efficient clofilium tosylate-mediated rescue of POLG-related disease phenotypes in zebrafish
2021 Facchinello, Nicola; Laquatra, Claudio; Locatello, Lisa; Beffagna, Giorgia; Brañas Casas, Raquel; Fornetto, Chiara; Dinarello, Alberto; Martorano, Laura; Vettori, Andrea; Risato, Giovanni; Celeghin, Rudy; Meneghetti, Giacomo; Santoro, Massimo Mattia; Delahodde, Agnes; Vanzi, Francesco; Rasola, Andrea; Dalla Valle, Luisa; Rasotto, Maria Berica; Lodi, Tiziana; Baruffini, Enrico; Argenton, Francesco; Tiso, Natascia
Hexokinase 2 in Cancer: A Prima Donna Playing Multiple Characters
2021 Ciscato, F.; Ferrone, L.; Masgras, I.; Laquatra, C.; Rasola, A.
HIF1α-dependent induction of the mitochondrial chaperone TRAP1 regulates bioenergetic adaptations to hypoxia
2021 Laquatra, C.; Sanchez-Martin, C.; Dinarello, A.; Cannino, G.; Minervini, G.; Moroni, E.; Schiavone, M.; Tosatto, S.; Argenton, F.; Colombo, G.; Bernardi, P.; Masgras, I.; Rasola, A.
Modulation and Pharmacology of the Mitochondrial Permeability Transition: A Journey from F-ATP Synthase to ANT
2021 Carrer, Andrea; Laquatra, Claudio; Tommasin, Ludovica; Carraro, Michela
The molecular chaperone TRAP1 in cancer: From the basics of biology to pharmacological targeting
2021 Masgras, I.; Laquatra, C.; Cannino, G.; Serapian, S. A.; Colombo, G.; Rasola, A.
Rational Design of Allosteric and Selective Inhibitors of the Molecular Chaperone TRAP1
2020 Sanchez-Martin, C.; Moroni, E.; Ferraro, M.; Laquatra, C.; Cannino, G.; Masgras, I.; Negro, A.; Quadrelli, P.; Rasola, A.; Colombo, G.
The zebrafish orthologue of the human hepatocerebral disease gene MPV17 plays pleiotropic roles in mitochondria
2019 Martorano, Laura; Peron, Margherita; Laquatra, Claudio; Lidron, Elisa; Facchinello, Nicola; Meneghetti, Giacomo; Tiso, Natascia; Rasola, Andrea; Ghezzi, Daniele; Argenton, Francesco