POLETTI, VALENTINA
POLETTI, VALENTINA
Dipartimento di Salute della Donna e del Bambino - SDB
An empowered, clinically-viable hematopoietic stem cell gene therapy approach for the treatment of multisystemic Mucopolysaccharidosis Type II
2024 Das, Sabyasachi; Rruga, Fatlum; Montepeloso, Annita; Dimartino, Agnese; Spadini, Silvia; Corre, Guillaume; Patel, Janki; Cavalca, Eleonora; Ferro, Francesca; Gatti, Alessandra; Milazzo, Rita; Galy, Anne; Politi, Letterio S.; Rizzardi, Gian Paolo; Vallanti, Giuliana; Poletti, Valentina; Biffi, Alessandra
An innovative hematopoietic stem cell gene therapy approach benefits CLN1 disease in the mouse model
2023 Peviani, Marco; Das, Sabyasachi; Patel, Janki; Jno-Charles, Odella; Kumar, Rajesh; Zguro, Ana; Mathews, Tyler D; Cabras, Paolo; Milazzo, Rita; Cavalca, Eleonora; Poletti, Valentina; Biffi, Alessandra
An Optimized Lentiviral Vector Efficiently Corrects the Human Sickle Cell Disease Phenotype
2018 Weber, Leslie; Poletti, Valentina; Magrin, Elisa; Antoniani, Chiara; Martin, Samia; Bayard, Charles; Sadek, Hanem; Felix, Tristan; Meneghini, Vasco; Antoniou, Michael N.; El-Nemer, Wassim; Mavilio, Fulvio; Cavazzana, Marina; Andre-Schmutz, Isabelle; Miccio, Annarita
Biosafety Studies of a Clinically Applicable Lentiviral Vector for the Gene Therapy of Artemis-SCID
2019 Charrier, Sabine; Lagresle-Peyrou, Chantal; Poletti, Valentina; Rothe, Michael; Cédrone, Grégory; Gjata, Bernard; Mavilio, Fulvio; Fischer, Alain; Schambach, Axel; de Villartay, Jean-Pierre; Cavazzana, Marina; Hacein-Bey-Abina, Salima; Galy, Anne
Constraints on Human CD34+ Cell Fate due to Lentiviral Vectors Can Be Relieved by Valproic Acid
2019 Moussy, Alice; Papili Gao, Nan; Corre, Guillaume; Poletti, Valentina; Majdoul, Saliha; Fenard, David; Gunawan, Rudiyanto; Stockholm, Daniel; Páldi, András
Correction of laminin-5 deficiency in human epidermal stem cells by transcriptionally targeted lentiviral vectors.
2008 Di Nunzio, F; Maruggi, G; Ferrari, S; DI IORIO, MARIO VINCENZO; Poletti, V; Garcia, M; Del Rio, M; De Luca, M; Larcher, F; Pellegrini, G; Mavilio, F.
Designing Lentiviral Vectors for Gene Therapy of Genetic Diseases
2021 Poletti, Valentina; Mavilio, Fulvio
Efficient Non-viral Gene Delivery into Human Hematopoietic Stem Cells by Minicircle Sleeping Beauty Transposon Vectors
2018 Holstein, Marta; Mesa-Nuñez, Cristina; Miskey, Csaba; Almarza, Elena; Poletti, Valentina; Schmeer, Marco; Grueso, Esther; Ordóñez Flores, Juan Carlos; Kobelt, Dennis; Walther, Wolfgang; Aneja, Manish K.; Geiger, Johannes; Bonig, Halvard B.; Izsvák, Zsuzsanna; Schleef, Martin; Rudolph, Carsten; Mavilio, Fulvio; Bueren, Juan A.; Guenechea, Guillermo; Ivics, Zoltán
Gene Therapy for Sickle Cell Disease:A Lentiviral Vector Comparison Study
2018 Urbinati, Fabrizia; Campo Fernandez, Beatriz; Masiuk, Katelyn E.; Poletti, Valentina; Hollis, Roger P.; Koziol, Colin; Kaufman, Michael L.; Brown, Devin; Mavilio, Fulvio; Kohn, Donald B.
Gene-Based Approaches to Inherited Neurometabolic Diseases
2019 Poletti, V.; Biffi, A.
Genome-Wide Definition of Promoter and Enhancer Usage during Neural Induction of Human Embryonic Stem Cells
2015 Poletti, Valentina; Delli Carri, Alessia; Malagoli Tagliazucchi, Guidantonio; Faedo, Andrea; Petiti, Luca; Mazza, Emilia Maria Cristina; Peano, Clelia; De Bellis, Gianluca; Bicciato, Silvio; Miccio, Annarita; Cattaneo, Elena; Mavilio, Fulvio
Interactions between Retroviruses and the Host Cell Genome
2018 Poletti, Valentina; Mavilio, Fulvio
Multiple Integrated Non-clinical Studies Predict the Safety of Lentivirus-Mediated Gene Therapy for β-Thalassemia
2018 Lidonnici, Maria Rosa; Paleari, Ylenia; Tiboni, Francesca; Mandelli, Giacomo; Rossi, Claudia; Vezzoli, Michela; Aprile, Annamaria; Lederer, Carsten Werner; Ambrosi, Alessandro; Chanut, Franck; Sanvito, Francesca; Calabria, Andrea; Poletti, Valentina; Mavilio, Fulvio; Montini, Eugenio; Naldini, Luigi; Cristofori, Patrizia; Ferrari, Giuliana
Novel lentiviral vectors for gene therapy of sickle cell disease combining gene addition and gene silencing strategies
2023 Brusson, Mégane; Chalumeau, Anne; Martinucci, Pierre; Romano, Oriana; Felix, Tristan; Poletti, Valentina; Scaramuzza, Samantha; Ramadier, Sophie; Masson, Cecile; Ferrari, Giuliana; Mavilio, Fulvio; Cavazzana, Marina; Amendola, Mario; Miccio, Annarita
Pre-clinical Development of a Lentiviral Vector Expressing the Anti-sickling βAS3 Globin for Gene Therapy for Sickle Cell Disease
2018 Poletti, Valentina; Urbinati, Fabrizia; Charrier, Sabine; Corre, Guillaume; Hollis, Roger P.; Campo Fernandez, Beatriz; Martin, Samia; Rothe, Michael; Schambach, Axel; Kohn, Donald B.; Mavilio, Fulvio
Preclinical Development of a Lentiviral Vector for Gene Therapy of X-Linked Severe Combined Immunodeficiency
2018 Poletti, Valentina; Charrier, Sabine; Corre, Guillaume; Gjata, Bernard; Vignaud, Alban; Zhang, Fang; Rothe, Michael; Schambach, Axel; Gaspar, H. Bobby; Thrasher, Adrian J.; Mavilio, Fulvio
Preclinical Development of an Ex Vivo Gene Therapy for GM1-Gangliosidosis
2020 Poletti, V; Biffi, A
Preclinical Development of an Ex Vivo Gene Therapy for Mucopolysaccharidosis Type II
2022 Das, S; Rruga, F; Rigon, L; Patel, J; Milazzo, R; Poletti, V; Biffi, A
Prostaglandin E2 as transduction enhancer affects competitive engraftment of human hematopoietic stem and progenitor cells
2023 Poletti, Valentina; Montepeloso, Annita; Pellin, Danilo; Biffi, Alessandra
Retroviral scanning: Mapping MLV integration sites to define cell-specific regulatory regions
2017 Romano, O.; Cifola, I.; Poletti, V.; Severgnini, M.; Peano, C.; de Bellis, G.; Mavilio, F.; Miccio, A.