TROLESE, PHILIPP
TROLESE, PHILIPP
Dipartimento di Scienze del Farmaco - DSF
Differential roles of proteasome and autophagy in α-synuclein and E46K oligomer clearance: insight into the modulatory effects of the dopamine metabolite DOPAC
2026 Leri, Manuela; Trolese, Philipp; Inciardi, Ilenia; Polverino De Laureto, Patrizia; Bucciantini, Monica
Mapping Structure Dependent Oxidation and Deamidation in Monoclonal Antibodies for Stability Assessment
2026 Fongaro, B.; Trolese, P.; Scapin, Vittoria; Polo-Megías, Daniel; Minervini Giovanni Conejero-Lara, Francisco; Polverino De Laureto, P.
Neutralizing nanobodies against SARS-CoV-2 recognizing highly conserved epitopes at the Spike's S2 subunit
2026 Polo-Megías, Daniel; Cano-Muñoz, Mario; Trolese, Philipp; Lestani, Sara; La Rocchia, Ilaria; Pierangelini, Andrea; Fongaro, Benedetta; Polverino De Laureto, Patrizia; J Morales-Yánez, Francisco; Vaneyck, Jonathan; Vanderplasschen, Alain; Decoville, Thomas; Laumond, Géraldine; Carmen Salinas-Garcia, M; Cámara-Artigas, Ana; A Gavira, José; Moog, Christiane; Dumoulin, Mireille; Conejero-Lara, Francisco
Probing the role of α-synuclein extreme N-terminus in membrane interactions and aggregation by structural mass spectrometry.
2026 Trolese, P.; Fongaro, B.; Acquasaliente, L.; Polverino De Laureto, P.
Role of N-Terminus in α-Synuclein Conformations
2026 Trolese, P.; Fongaro, B.; Acquasaliente, L.; Polverino De Laureto, P
The extreme N-terminus modulates α-synuclein membrane interactions, aggregation and conformational dynamics
2026 Trolese, P.; Fongaro, B.; Sosic, A.; Acquasaliente, L.; Polverino De Laureto, P.
An L-DOPA-PLP cyclic adduct exerts oxidative stress on ⍺-Synuclein
2025 Trolese, Philipp; Bisello, Giovanni; Fongaro, Benedetta; Acquasaliente, Laura; Polverino De Laureto, Patrizia; Bertoldi, M.
Biophysical analysis of DOPAC-induced alterations in ⍺-Synuclein and E46K membrane binding dynamics
2025 Trolese, Philipp; Fongaro, Benedetta; Acquasaliente, Laura; Polverino De Laureto, Patrizia
DOPAC as a modulator of α-Synuclein and E46K interactions with membrane: Insights into binding dynamics
2025 Rizzotto, Elena; Pierangelini, Andrea; Fongaro, Benedetta; Leri, Manuela; Inciardi, Ilenia; Trolese, Philipp; De Filippis, Vincenzo; Bucciantini, Monica; Acquasaliente, Laura; Polverino de Laureto, Patrizia
HDX-MS Reveals Regions Prone to Aggregation In a mAb Exposed To pH Stress
2025 Trolese, Philipp; Fongaro, Benedetta; Scapin, V.; Pierangelini, A.; Miolo, Giorgia; Polverino De Laureto, Patrizia
Interdomain Interactions Modulate Refolding Kinetics and Aggregation in a Monoclonal Antibody
2025 Trolese, Philipp; Pierangelini, Andrea; Fongaro, Benedetta; Polverino De Laureto, Patrizia
Native-MS as a suitable tool to select new scaffold for the inhibition of protein aggregation
2025 Fongaro, Benedetta; Trolese, Philipp; Scapin, Vittoria; Sosic, Alice; Acquasaliente, Laura; Polverino De Laureto, Patrizia
The aggregation kinetics of α-Synuclein is highly dependent on the protein dynamics in the native state
2025 Fongaro, Benedetta; Trolese, Philipp; Scapin, Vittoria; Sosic, Alice; Acquasaliente, Laura; Polverino De Laureto, Patrizia
The native-state dynamics of α-Synuclein plays a crucial role in determining its aggregation kinetics
2025 Fongaro, Benedetta; Trolese, Philipp; Scapin, V.; Sosic, Alice; Acquasaliente, Laura; Polverino De Laureto, Patrizia
Light and pH effects on Ipilimumab conformational stability
2024 Fongaro, Benedetta; Rizzotto, Elena; Inciardi, Ilenia; Trolese, Philipp; Pierangelini, Andrea; Acquasaliente, Laura; Miolo, Giorgia; Polverino De Laureto, Patrizia
Light exacerbates local and global effects induced by pH unfolding of Ipilimumab
2024 Rizzotto, Elena; Inciardi, Ilenia; Fongaro, Benedetta; Trolese, Philipp; Miolo, Giorgia; POLVERINO DE LAURETO, Patrizia