BONOMINI, ANNA
BONOMINI, ANNA
Dipartimento di Medicina Molecolare - DMM
1,2,4-Triazolo[1,5-a]pyrimidines: Efficient one-step synthesis and functionalization as influenza polymerase PA-PB1 interaction disruptors
2021 Pismataro, M. C.; Felicetti, T.; Bertagnin, C.; Nizi, M. G.; Bonomini, A.; Barreca, M. L.; Cecchetti, V.; Jochmans, D.; De Jonghe, S.; Neyts, J.; Loregian, A.; Tabarrini, O.; Massari, S.
A novel N-heterocycles substituted oseltamivir derivatives as potent inhibitors of influenza virus neuraminidase: discovery, synthesis and biological evaluation
2023 Zhang, J.; Liu, C.; Jia, R.; Zhang, X.; Zhang, J.; Bertagnin, C.; Bonomini, A.; Guizzo, L.; Jiang, Y.; Jia, H.; Jia, S.; Ma, X.; Loregian, A.; Huang, B.; Zhan, P.; Liu, X.
Discovery of N-substituted oseltamivir derivatives as novel neuraminidase inhibitors with improved drug resistance profiles and favorable drug-like properties
2023 Jia, R.; Zhang, J.; Shi, F.; Bonomini, A.; Lucca, C.; Bertagnin, C.; Zhang, J.; Liu, C.; Jia, H.; Jiang, Y.; Ma, X.; Loregian, A.; Huang, B.; Zhan, P.; Liu, X.
Discovery of Novel Boron-Containing N-Substituted Oseltamivir Derivatives as Anti-Influenza A Virus Agents for Overcoming N1-H274Y Oseltamivir-Resistant
2022 Jia, Ruifang; Zhang, Jiwei; Zhang, Jian; Bertagnin, Chiara; Bonomini, Anna; Guizzo, Laura; Gao, Zhen; Ji, Xiangkai; Li, Zhuo; Liu, Chuanfeng; Ju, Han; Ma, Xiuli; Loregian, Arianna; Huang, Bing; Zhan, Peng; Liu, Xinyong
Exploring a New Generation of Pyrimidine and Pyridine Derivatives as Anti-Influenza Agents Targeting the Polymerase PA–PB1 Subunits Interaction
2024 Giacchello, I.; Cianciusi, A.; Bertagnin, C.; Bonomini, A.; Francesconi, V.; Mori, M.; Carbone, A.; Musumeci, F.; Loregian, A.; Schenone, S.
Iterative Optimization and Structure-Activity Relationship Studies of Oseltamivir Amino Derivatives as Potent and Selective Neuraminidase Inhibitors via Targeting 150-Cavity
2022 Ju, Han; Hou, Lingxin; Zhao, Fabao; Zhang, Ying; Jia, Ruifang; Guizzo, Laura; Bonomini, Anna; Zhang, Jiwei; Gao, Zhen; Liang, Ruipeng; Bertagnin, Chiara; Kong, Xiujie; Ma, Xiuli; Kang, Dongwei; Loregian, Arianna; Huang, Bing; Liu, Xinyong; Zhan, Peng
Optimization of potent, broad-spectrum, and specific anti-influenza compounds targeting RNA polymerase PA-PB1 heterodimerization
2024 Bonomini, A.; Felicetti, T.; Pacetti, M.; Bertagnin, C.; Coletti, A.; Giammarino, F.; De Angelis, M.; Poggialini, F.; Macchiarulo, A.; Sabatini, S.; Mercorelli, B.; Nencioni, L.; Vicenti, I.; Dreassi, E.; Cecchetti, V.; Tabarrini, O.; Loregian, A.; Massari, S.
Sviluppo e caratterizzazione di nuovi inibitori dell'RNA polimerasi e della neuraminidasi del virus dell'influenza
2024 Bonomini, Anna
Switching the three-component Biginelli-like reaction conditions for the regioselective synthesis of new 2-amino[1,2,4]triazolo[1,5-a]pyrimidines
2024 Pacetti, Martina; Pismataro, Maria Chiara; Felicetti, Tommaso; Giammarino, Federica; Bonomini, Anna; Tiecco, Matteo; Bertagnin, Chiara; Barreca, Maria Letizia; Germani, Raimondo; Cecchetti, Violetta; Vicenti, Ilaria; Tabarrini, Oriana; Zazzi, Maurizio; Loregian, Arianna; Massari, Serena
Synergistic activity of an RNA polymerase PA-PB1 interaction inhibitor with oseltamivir against human and avian influenza viruses in cell culture and in ovo
2024 Bonomini, A.; Zhang, J.; Ju, H.; Zago, A.; Pacetti, M.; Tabarrini, O.; Massari, S.; Liu, X.; Mercorelli, B.; Zhan, P.; Loregian, A.