PALUMBO, MANLIO
 Distribuzione geografica
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Continente #
NA - Nord America 19.381
AS - Asia 4.872
EU - Europa 3.439
AF - Africa 1.150
SA - Sud America 1.018
OC - Oceania 111
Continente sconosciuto - Info sul continente non disponibili 56
Totale 30.027
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Nazione #
US - Stati Uniti d'America 18.816
SG - Singapore 1.565
CN - Cina 1.107
HK - Hong Kong 823
BR - Brasile 655
FI - Finlandia 481
DE - Germania 404
IT - Italia 299
VN - Vietnam 268
SE - Svezia 255
UA - Ucraina 255
PL - Polonia 228
FR - Francia 219
RU - Federazione Russa 196
GB - Regno Unito 167
NL - Olanda 122
IE - Irlanda 63
AR - Argentina 62
TR - Turchia 58
IN - India 57
IQ - Iraq 52
CI - Costa d'Avorio 50
MX - Messico 49
TT - Trinidad e Tobago 45
AT - Austria 44
ZA - Sudafrica 44
CO - Colombia 41
IR - Iran 41
LB - Libano 41
DZ - Algeria 40
UZ - Uzbekistan 40
CM - Camerun 38
MY - Malesia 38
PY - Paraguay 38
SO - Somalia 38
AZ - Azerbaigian 37
CV - Capo Verde 37
EC - Ecuador 37
GF - Guiana Francese 37
GM - Gambi 37
TH - Thailandia 37
JP - Giappone 36
PH - Filippine 36
VE - Venezuela 36
DK - Danimarca 35
IS - Islanda 35
JM - Giamaica 35
KE - Kenya 35
PA - Panama 35
TW - Taiwan 34
AL - Albania 33
BY - Bielorussia 33
CW - ???statistics.table.value.countryCode.CW??? 33
CZ - Repubblica Ceca 33
ES - Italia 33
JO - Giordania 33
KG - Kirghizistan 33
KH - Cambogia 33
KR - Corea 33
CH - Svizzera 32
LV - Lettonia 32
MR - Mauritania 32
NO - Norvegia 32
RS - Serbia 32
CA - Canada 31
CR - Costa Rica 31
DJ - Gibuti 31
NI - Nicaragua 31
PS - Palestinian Territory 31
CY - Cipro 30
GA - Gabon 30
MG - Madagascar 30
MN - Mongolia 30
PE - Perù 30
PT - Portogallo 30
RE - Reunion 30
AO - Angola 29
BJ - Benin 29
CD - Congo 29
EG - Egitto 29
GE - Georgia 29
IL - Israele 29
AE - Emirati Arabi Uniti 28
AU - Australia 28
CL - Cile 28
DO - Repubblica Dominicana 28
KZ - Kazakistan 28
LY - Libia 28
MZ - Mozambico 28
TJ - Tagikistan 28
BO - Bolivia 27
CG - Congo 27
GP - Guadalupe 27
MA - Marocco 27
NC - Nuova Caledonia 27
PK - Pakistan 27
TN - Tunisia 27
UY - Uruguay 27
BE - Belgio 26
BZ - Belize 26
Totale 28.766
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Città #
Fairfield 2.580
Woodbridge 2.253
Ann Arbor 1.594
Houston 1.516
Chandler 1.231
Ashburn 1.224
Jacksonville 1.216
Wilmington 1.025
Seattle 968
Cambridge 923
Singapore 844
Hong Kong 799
Princeton 471
Boardman 427
Santa Clara 426
Beijing 316
San Diego 287
Roxbury 240
Nanjing 206
Bytom 198
Medford 174
Dong Ket 173
Helsinki 152
Des Moines 113
Padova 70
Hebei 61
Norwalk 61
Shenyang 58
Los Angeles 52
Nanchang 52
São Paulo 50
Guangzhou 46
Abidjan 43
Changsha 43
Dublin 41
New York 39
Tianjin 39
Jiaxing 38
Munich 36
Baku 35
London 35
Tashkent 35
Panama City 33
Praia 33
Amman 31
Bishkek 31
Djibouti 31
Managua 30
Vienna 30
Cayenne 29
Ho Chi Minh City 29
Luanda 29
Phnom Penh 29
Ulan Bator 29
Libreville 28
Riga 28
Antananarivo 27
Nouakchott 27
Noumea 27
Buffalo 26
Cotonou 26
Dushanbe 26
Milan 26
Minsk 26
Bamako 25
Kingston 25
Nairobi 25
Washington 25
Conakry 24
Hanoi 24
Kinshasa 24
Reykjavik 24
San José 24
Castries 23
Dar es Salaam 23
Kigali 23
Willemstad 23
Accra 22
Banjul 22
Brooklyn 22
Kampala 22
Montevideo 22
Niamey 22
Stockholm 22
Harare 21
Tbilisi 21
Baghdad 20
Bridgetown 20
Chaguanas 20
Havana 20
Lima 19
Maputo 19
Nassau 19
Redwood City 19
Tirana 19
Vientiane 19
Dakar 18
Gaborone 18
Hargeisa 18
Indiana 18
Totale 21.595
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Nome #
Screening of candidate G-quadruplex ligands for the human c-KIT promotorial region and their effects in multiple in-vitro models 193
A Dynamic G-Quadruplex Region Regulates the HIV-1 Long Terminal Repeat Promoter 179
The topoisomerase II poison clerocidin alkylates non-paired guanines of DNA: implications for the irreversible stimulation of DNA cleavage 175
Benzo- and tetrahydrobenzo-psoralen congeners: DNA binding and photobiological properties 168
Relevance of DNA binding to the mechanism of anti-herpesvirus activity of benzhydrazone 165
The 6-Aminoquinolone WC5 Inhibits Human Cytomegalovirus Replication at an Early Stage by Interfering with the Transactivating Activity of Viral Immediate-Early 2 Protein 161
Virtual Cross-Linking of the Active Nemorubicin Metabolite PNU-159682 to Double-Stranded DNA 160
Analysis of topoisomerase (TOP) expression in peripheral blood mononuclear cell (PBMCs) from patients (PTS) undergoing chemotherapy (CHT) for solid tumors(ST) 160
A viable route to designable chiral macromolecular supports: Implications for supported metal catalysis 160
Rational Design, Synthesis, and DNA Binding Properties of Novel Sequence-Selective Peptidyl Congeners of Ametantrone 159
Effects of common buffer systems on drug activity: the case of clerocidin 159
6-aminoquinolones as new potential anti-HIV agents 159
Assessment of gene promoter G-quadruplex binding and modulation by a naphthalene diimide derivative in tumor cells 155
Molecular Basis for Differential Recognition of G-Quadruplex versus Double-Helix DNA by Bis-Phenanthroline Metal Complexes 155
BINOL quinone methides as bis-alkylating and DNA cross-linking agents 153
Quinone methides tethered to naphthalene diimides as selective G-quadruplex alkylating agents 152
Aza-isoindolo and isoindolo-azaquinoxaline derivatives with antiproliferative activity 152
A novel 9-aza-anthrapyrazole effective against human prostatic carcinoma xenografts 152
The cellular protein nucleolin preferentially binds long-looped G-quadruplex nucleic acids 151
Clerocidin alkylates DNA through its epoxide function: evidence for a fine tuned mechanism of action 150
BINOL-amino acid conjugates as triggerable carriers of DNA-targeted potent photocytotoxic agents 149
Synthesis and biological activity of new quinolone derivatives 146
Sequence specificity of psoralen photobinding to DNA: a quantitative approach 146
Novel Ametantrone-Amsacrine Related Hybrids as Topoisomerase II? Poisons and Cytotoxic Agents 146
Tuning G-quadruplex vs. double stranded DNA recognition in regioisomeric lysyl-peptidyl-anthraquinone conjugates 143
Aminoacyl-analogues of Mitoxantrone as novel DNA-damaging cytotoxic agents 143
Reactivity of Clerocidin towards adenine: implications for base modulated DNA damage 143
DNA gyrase requires DNA for effective two-site coordination of divalent metal ions: further insight into the mechanism of enzyme action 143
DNA-binding preferences of bisantrene analogues: Relevance to the sequence specificity of drug-mediated topoisomerase II poisoning 143
G-quadruplexes in human promoters: A challenge for therapeutic applications 143
Biologically relevant Cu2+ complexes with a tridentate phenanthroline analogue: structural properties and DNA damage 142
Aminoacyl-anthraquinone conjugates as telomerase inhibitors: synthesis, biophysical and biological evaluation 141
Methylfuroquinolinones: new furocoumarin isosters as potential photoreagents toward DNA. 139
Sequencing and G-quadruplex folding of the canine proto-oncogene KIT promoter region: might dog be used as a model for human disease? 139
The effects of metal ions on the structure and stability of the DNA gyrase B protein 138
DNA-Interactive Anticancer Aza-Anthrapyrazoles: Biophysical and Biochemical Studies Relevant to the Mechanism of Action 138
Ferric complexes of acetoacetyl derivatives of poly(L-lysine), poly(L-ornithine), and poly(L-diaminobutyric acid). II. Conformational properties in solution. Evidence for a stereospecific complex formation. 138
Nucleic acid aptamers based on the G-quadruplex structure: therapeutic and diagnostic potential 137
DNA phosphodiester bond hydrolysis mediated by Cu(II) and Zn(II) complexes of 1,3,5-triaminocyclohexane derivatives 137
Novel pyrrolo [3,2-f]quinolines: synthesis and antiproliferative activity 136
Interaction between the cytotoxic drug Clerocidin and DNA: evidence for covalent adduct formation 136
Benzofurocoumarins: new monofunctional DNA-photobinding agents 136
G-rich sequences within proto-oncogene KIT promoter region as targets for anticancer therapy. 136
Antiviral 6-amino-quinolones: Molecular basis for potency and selectivity. 135
Fast atom bombardment mass spectrometry of some pharmacologically relevant anthraquinone derivatives 135
Concerted bis-alkylating reactivity of clerocidin towards unpaired cytosine residues in DNA 133
Antiviral properties of quinolone-based drugs. 133
Impairment of c-kit expression in human cancer cell lines by a novel pharmacophoric unit selected for the recognition of the proto-oncogene KIT promotorial region. 133
2-phenylquinolones as inhibitors of the HIV-1 Tat/TAR interaction. 133
Clerocidin interacts with the cleavage complex of Streptococcus pneumoniae topoisomerase IV to induce selective irreversible DNA damage 132
Hot-spot consensus of fluoroquinolone-mediated DNA cleavage by gram-negative and gram-positive type II DNA topoisomerases 132
Formation of a Unique Cluster of G-Quadruplex Structures in the HIV-1 nef Coding Region: Implications for Antiviral Activity 132
Quinolone binding to DNA is mediated by magnesium ions 132
Ferric complexes of acetoacetyl derivatives of poly(L-lysine), poly(L-ornithine), and poly(L-diaminobutyric acid). I. Preparation and absorption properties in solution. 132
On the mechanism of action of quinolone drugs 131
Telomeric G-quadruplex architecture and interactions with potential drugs 130
Dinuclear Zn2+ complexes of synthetic heptapeptides as artificial nucleases 130
Effects of Magnesium and related divalent metal ions in topoisomerase structure and function 129
In vitro basis for schedule-dependent interaction between gemcitabine and topoisomerase-targeted drugs in the treatment of colorectal cancer 129
Targeting Loop Adenines in G-Quadruplex by a Selective Oxirane 129
Folding versus charge: understanding selective target recognition by the thrombin aptamers 128
Amide bond direction modulates G-quadruplex recognition and telomerase inhibition by 2,6 and 2,7 bis-substituted anthracenedione derivatives. 128
A potentiometric and CD investigation on the conformational properties of poly(L-p-aminophenylalanine) in aqueous solution. 128
In vitro Selection of DNA Aptamers that Bind L-Tyrosinamide 128
Clerocidin-mediated DNA footprinting discriminates among different G-quadruplex conformations and detects tetraplex folding in a duplex environment 126
Targeting canine c-KIT promoter by a candidate DNA G-quadruplex ligand 126
Water-soluble isoindolo[2,1-a]quinoxalin-6-imines: In vitro antiproliferative activity and molecular mechanism(s) of action 126
Interaction of metal ions with gastrointestinal hormones: binding studies of Mg++ to biologically active analogs of little gastrin and minigastrin. 126
Effect of chemotherapy on topoisomerase (TOP) expression and activity in colon carcinoma cells 125
Potent 6-desfluoro-8-methylquinolones as new lead compounds in antibacterial chemotherapy 125
New hydroxy-amido-anthraquinones as potential antineoplastic drugs 125
Synthesis, DNA-damaging and cytotoxic properties of novel topoisomerase II-directed bisantrene analogues 124
Synthesis of 2H,9H-naphtho[2,3-b:7,6-b']dipyran-2,9-diones as potential DNA-reactive agents 124
The effect of the minor groove binding agent DAPI (4', 6-diamidino-2-phenyl-indole) on DNA-directed enzymes: an attempt to explain inhibition of plasmid expression in Escherichia coli 123
Pyrrolocoumarin derivatives: DNA-binding properties 123
Quinone Methide Generation via Photoinduced Electron Transfer 122
Tuning the activity of Zn(II) complexes in DNA cleavage: Clues for design of new efficient metallo-hydrolases 122
Ni2+ and Cu2+ complexes of a phenanthroline-based ligand bind to G-quadruplexes at non-overlapping sites 122
Involvement of p53 in specific anti-neuroectodermal tumor activity of aloe-emodin 122
Conformation and Stability of Intramolecular Telomeric G-Quadruplexes: Sequence Effects in the Loops 122
Targeting canine kit promoter by candidate DNA G-quadruplex ligands 122
Mapping drug interactions at the covalent topoisomerase II-DNA complex by bisantrene/amsacrine congeners 121
Topoisomerase I involvement in schedule-dependent interaction between 5-fluoro-uracil and irinotecan in the treatment of colorectal cancer. 120
Studies on Anti-HIV Transcription Inhibitor Quinolones: Identification of Potent N-1-Vinyl Derivatives 120
New anti-human immunodeficiency type 1 6-aminoquinolones: mechanism of action 120
Alternative approaches to the discovery and development of telomerase-targeted anticancer drugs 120
Physicochemical properties, cytotoxic activity and topoisomerase II inhibition of 2,3-diaza-anthracenediones 119
A protein-mediated mechanism for the DNA sequence-specific action of topoisomerase II poisons - 119
Inhibition of human immunodeficiency virus type 1 tat-trans-activation-responsive region interaction by an antiviral quinolone derivative 118
Naphthalene diimide scaffolds with dual reversible and covalent interaction properties towards G-quadruplex 118
Adjustable 'cross-linking' of neighboring DNA molecules in liquid-crystalline dispersions through (daunomycin-copper) polymeric chelate complexes 118
Synthesis and photobiological properties of 4- hydroxymethyl-4'- methylpsoralen derivatives. 117
Bis-phenanthroline derivatives as suitable scaffolds for effective G-quadruplex recognition 116
A Dynamic G-Quadruplex Region Regulates the HIV-1 Long Terminal Repeat Promoter 116
A G-quadruplex binding compound down-regulates KIT, BCL2 and PDGFRβ expression in human gastric carcinoma cell line 116
Modulation of Antithrombin-Protease Interactions by Semisynthetic Low-Molecular-Weight Heparins with Different Sulfation Patterns 115
Conformational aspects of drug-DNA interactions: Studies on anthracycline antibiotics and psoralen derivatives 114
Interactions of low-molecular-weight semi-synthetic sulfated heparins with human leukocyte elastase and human Cathepsin G 113
Efficient Plasmid DNA Cleavage by a Mononuclear Copper(II) Complex 113
A search for potential antitumor agents: biological effects and DNA binding of a series of anthraquinone derivatives. 113
Totale 13.539
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Categoria #
all - tutte 96.049
article - articoli 85.327
book - libri 454
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 641
selected - selezionate 0
volume - volumi 2.065
Totale 184.536
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20212.469 0 0 53 231 177 303 75 281 447 239 362 301
2021/20223.682 76 476 544 246 131 144 153 406 157 62 430 857
2022/20232.532 601 266 49 297 409 330 5 151 287 5 97 35
2023/20241.036 46 168 136 67 91 108 51 31 25 27 150 136
2024/20255.025 11 287 304 190 811 132 197 322 535 149 812 1.275
2025/20264.776 440 1.800 2.536 0 0 0 0 0 0 0 0 0
Totale 30.130