GATTO, BARBARA
 Distribuzione geografica
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Continente #
NA - Nord America 10.850
AS - Asia 5.502
EU - Europa 4.360
AF - Africa 922
SA - Sud America 898
OC - Oceania 105
Continente sconosciuto - Info sul continente non disponibili 43
Totale 22.680
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Nazione #
US - Stati Uniti d'America 10.364
IT - Italia 2.158
SG - Singapore 1.966
CN - Cina 986
VN - Vietnam 688
BR - Brasile 536
HK - Hong Kong 450
FR - Francia 286
DE - Germania 228
FI - Finlandia 222
IN - India 184
NL - Olanda 157
GB - Regno Unito 153
UA - Ucraina 143
SE - Svezia 124
RU - Federazione Russa 112
TR - Turchia 95
PL - Polonia 94
IQ - Iraq 90
AR - Argentina 79
BD - Bangladesh 75
JP - Giappone 63
PK - Pakistan 61
MX - Messico 56
CA - Canada 52
ZA - Sudafrica 50
ID - Indonesia 48
KR - Corea 47
PH - Filippine 47
SA - Arabia Saudita 47
CO - Colombia 40
EC - Ecuador 40
UZ - Uzbekistan 39
AT - Austria 38
IR - Iran 37
MA - Marocco 37
ML - Mali 36
VE - Venezuela 36
CL - Cile 35
ES - Italia 35
AU - Australia 34
KZ - Kazakistan 34
AE - Emirati Arabi Uniti 33
BE - Belgio 33
KE - Kenya 33
MY - Malesia 33
PY - Paraguay 33
TH - Thailandia 33
TN - Tunisia 33
ET - Etiopia 32
GM - Gambi 32
JM - Giamaica 32
JO - Giordania 32
HU - Ungheria 31
LB - Libano 31
RS - Serbia 31
CH - Svizzera 30
CZ - Repubblica Ceca 30
GR - Grecia 30
AZ - Azerbaigian 29
CV - Capo Verde 29
DZ - Algeria 29
EG - Egitto 29
CY - Cipro 28
HR - Croazia 28
IL - Israele 28
NP - Nepal 28
AO - Angola 27
BO - Bolivia 27
CM - Camerun 27
HN - Honduras 27
IE - Irlanda 27
PE - Perù 27
PT - Portogallo 27
TT - Trinidad e Tobago 27
XK - ???statistics.table.value.countryCode.XK??? 27
NI - Nicaragua 26
SK - Slovacchia (Repubblica Slovacca) 26
TW - Taiwan 26
BY - Bielorussia 25
CR - Costa Rica 25
GA - Gabon 25
IS - Islanda 25
LA - Repubblica Popolare Democratica del Laos 25
DO - Repubblica Dominicana 24
SI - Slovenia 24
DK - Danimarca 23
GN - Guinea 23
KH - Cambogia 23
MN - Mongolia 23
PS - Palestinian Territory 23
UY - Uruguay 23
BB - Barbados 22
BW - Botswana 22
CI - Costa d'Avorio 22
GH - Ghana 22
SN - Senegal 22
TJ - Tagikistan 22
ZW - Zimbabwe 22
AD - Andorra 21
Totale 21.679
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Città #
Singapore 1.326
Ashburn 1.171
Fairfield 1.155
Woodbridge 930
San Jose 860
Houston 745
Chandler 599
Ann Arbor 570
Jacksonville 525
Wilmington 431
Seattle 397
Hong Kong 390
Cambridge 373
Ho Chi Minh City 202
Beijing 200
Princeton 193
Santa Clara 183
Hanoi 179
Milan 163
Boardman 156
Rome 149
Padova 142
San Diego 120
Los Angeles 108
Lauterbourg 107
Naples 101
Helsinki 89
Nanjing 80
Council Bluffs 68
Medford 63
Roxbury 61
São Paulo 55
New York 54
Bytom 53
Des Moines 50
Guangzhou 49
Da Nang 47
The Dalles 41
Tokyo 41
Chicago 40
Buffalo 35
Munich 35
Baghdad 34
Tashkent 34
Bamako 33
Genoa 31
Hefei 30
Amman 29
Redondo Beach 29
Bologna 28
Haiphong 28
London 28
Addis Ababa 27
Baku 27
Shenyang 27
Vienna 26
Luanda 25
Norwalk 25
Shanghai 25
Stockholm 25
Turin 25
Nairobi 24
Florence 23
Frankfurt am Main 23
Jeddah 23
Managua 23
Parma 22
Praia 22
Reykjavik 22
Ulan Bator 22
Vientiane 22
Abidjan 21
Atlanta 21
Conakry 21
Dakar 21
Dushanbe 21
Harare 21
Kingston 21
Libreville 21
Lusaka 21
Orem 21
Bari 20
Dong Ket 20
Johannesburg 20
Nanchang 20
Niamey 20
Panama City 20
Phnom Penh 20
Pristina 20
Sydney 20
Accra 19
Andorra la Vella 19
Belgrade 19
Bridgetown 19
Dallas 19
Istanbul 19
Toronto 19
Bishkek 18
Montreal 18
Padua 18
Totale 13.675
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Nome #
Dall’evoluzione in vitro alle nanotecnologie: gli aptameri come biosensori 2.170
Behind the Mirror: Chirality Tunes the Reactivity and Cytotoxicity of Chloropiperidines as Potential Anticancer Agents 341
Cellular pharmacology of PNU-159682, a liver microsomal metabolite of methoxymorpholinyl doxorubicin (Nemorubicin; MMDX) 308
A new inactive conformation of SARS-CoV-2 main protease 264
Biologics targeted at TNF: design, production and challenges 262
The 6-Aminoquinolone WC5 Inhibits Human Cytomegalovirus Replication at an Early Stage by Interfering with the Transactivating Activity of Viral Immediate-Early 2 Protein 261
Identification of novel 2-benzoxazolinone derivatives with specific inhibitory activity against the HIV-1 nucleocapsid protein 256
Aromatic Linkers Unleash the Antiproliferative Potential of 3-Chloropiperidines Against Pancreatic Cancer Cells 250
Non-Natural Linker Configuration in 2,6-Dipeptidyl-Anthraquinones Enhances the Inhibition of TAR RNA Binding/Annealing Activities by HIV-1 NC and Tat Proteins 248
Virtual Cross-Linking of the Active Nemorubicin Metabolite PNU-159682 to Double-Stranded DNA 246
Computationally driven discovery of SARS-CoV-2 Mpro inhibitors: from design to experimental validation 245
Rational Design, Synthesis, and DNA Binding Properties of Novel Sequence-Selective Peptidyl Congeners of Ametantrone 238
Synthesis and in Vitro Screening of New Series of 2,6-Dipeptidyl-anthraquinones: Influence of Side Chain Length on HIV-1 Nucleocapsid Inhibitors 238
Quinolino[3,4-b]quinoxalines and pyridazino[4,3-c]quinoline derivatives: Synthesis, inhibition of topoisomerase IIα, G-quadruplex binding and cytotoxic properties 237
Aminoacyl-analogues of Mitoxantrone as novel DNA-damaging cytotoxic agents 232
The topoisomerase II poison clerocidin alkylates non-paired guanines of DNA: implications for the irreversible stimulation of DNA cleavage 231
Mechanisms of HIV-1 Nucleocapsid Protein Inhibition by Lysyl-Peptidyl-Anthraquinone Conjugates 225
Effects of common buffer systems on drug activity: the case of clerocidin 224
6-aminoquinolones as new potential anti-HIV agents 224
Appended Aromatic Moieties in Flexible Bis‐3‐chloropiperidines Confer Tropism against Pancreatic Cancer Cells 224
Design and synthesis of wm5 analogues as HIV-1 TAR RNA binders 223
Indenocinnoline derivatives as G-quadruplex binders, topoisomerase IIα inhibitors and antiproliferative agents 218
New anti-human immunodeficiency type 1 6-aminoquinolones: mechanism of action 214
Clerocidin alkylates DNA through its epoxide function: evidence for a fine tuned mechanism of action 212
Novel pyrrolo [3,2-f]quinolines: synthesis and antiproliferative activity 210
Development of a Multiplex Sandwich Aptamer Microarray for the Detection of VEGF165 and Thrombin 209
Multiple in Vitro Inhibition of HIV-1 Proteins by 2,6-Dipeptidyl-anthraquinone Conjugates Targeting the PBS RNA 209
Allostery in homodimeric SARS-CoV-2 main protease 208
Development and Optimization of a Thrombin Sandwich Aptamer Microarray 207
DNA minor groove-binding ligands: A different class of mammalian DNA topoisomerase I inhibitors 205
Differential poisoning of topoisomerases by menogaril and nogalamycin dictated by the minor groove-binding nogalose sugar 202
Nucleic acid aptamers based on the G-quadruplex structure: therapeutic and diagnostic potential 201
Bis-3-chloropiperidines containing bridging lysine linkers: Influence of side chain structure on DNA alkylating activity 200
DNA-Interactive Anticancer Aza-Anthrapyrazoles: Biophysical and Biochemical Studies Relevant to the Mechanism of Action 198
Antiviral 6-amino-quinolones: Molecular basis for potency and selectivity. 198
Involvement of p53 in specific anti-neuroectodermal tumor activity of aloe-emodin 196
In Vitro Chemical Mapping of G-Quadruplex DNA Structures by Bis-3-Chloropiperidines 193
Nucleocapsid Annealing-Mediated Electrophoresis (NAME) Assay Allows the Rapid Identification of HIV-1 Nucleocapsid Inhibitors 193
2-phenylquinolones as inhibitors of the HIV-1 Tat/TAR interaction. 188
2-Phenylquinolones as inhibitors of the HIV-1 Tat-TAR interaction 187
Bis-3-Chloropiperidines Targeting TAR RNA as A Novel Strategy to Impair the HIV-1 Nucleocapsid Protein 185
On the mechanism of action of quinolone drugs 184
Clerocidin interacts with the cleavage complex of Streptococcus pneumoniae topoisomerase IV to induce selective irreversible DNA damage 181
Design, synthesis and biological evaluation of TAR and cTAR binders as HIV-1 nucleocapsid inhibitors 180
Coralyne and related compounds as mammalian topoisomerase I and topoisomerase II poisons 179
In vitro Selection of DNA Aptamers that Bind L-Tyrosinamide 178
Enzymatic Formation of PEGylated Oligonucleotides 177
From Proteins to Nucleic Acid-Based Drugs: The Role of Biotech in Anti-VEGF Therapy 176
Mapping drug interactions at the covalent topoisomerase II-DNA complex by bisantrene/amsacrine congeners 175
B-CePs as cross-linking probes for the investigation of RNA higher-order structure 174
In Vitro Evaluation of Bis-3-Chloropiperidines as RNA Modulators Targeting TAR and TAR-Protein Interaction 174
Decoding mechanism of action and sensitivity to drug candidates from integrated transcriptome and chromatin state 172
Design, Synthesis and Biological Properties of New Bis(acridine-4-carboxamides) as Anticancer Agents 172
Quinolone binding to DNA is mediated by magnesium ions 172
Structure-activity relationships of benzimidazoles and related heterocycles as topoisomerase I poisons 171
Antracyclines: recent developments in their separation and quantitation 171
Interaction between the cytotoxic drug Clerocidin and DNA: evidence for covalent adduct formation 171
DNA topoisomerase-targeted drugs 167
Understanding the Alkylation Mechanism of 3‐Chloropiperidines – NMR Kinetic Studies and Isolation of Bicyclic Aziridinium Ions 167
Multifaceted Aspects of HIV-1 Nucleocapsid Inhibition by TAR-Targeting Peptidyl-Anthraquinones Bearing Terminal Aromatic Moieties 166
Effective DNA inhibitors of Cathepsin G by in vitro selection 165
Direct and Topoisomerase II Mediated DNA Damage by Bis-3-chloropiperidines: The Importance of Being an Earnest G 164
Peptidyl anthraquinones as potential antineoplastic drugs: synthesis, DNA-binding, redox cycling and biological activity 163
Studies on Anti-HIV Transcription Inhibitor Quinolones: Identification of Potent N-1-Vinyl Derivatives 162
Synthesis and evaluation of terbenzimidazoles as topoisomerase I inhibitors 162
Human Thrombin Detection Through a Sandwich Aptamer Microarray: Interaction Analysis in Solution and in Solid Phase. 161
Monoclonal antibodies in cancer therapy 159
Mg2+-mediated binding of 6-substituted quinolones to DNA: Relevance to biological activity 158
Topoisomerase I-targeting drugs: new developments in cancer pharmacology 155
The evolving world of protein-G-quadruplex recognition: a medicinal chemist's perspective 155
Synthesis and evaluation of a bis-3-chloropiperidine derivative incorporating an anthraquinone pharmacophore 154
Inhibition of human immunodeficiency virus type 1 tat-trans-activation-responsive region interaction by an antiviral quinolone derivative 153
Further insight into the Zn2+-mediated binding of streptonigrin to DNA 153
Drugs acting on the beta isoform of human topoisomerase II (p180) 152
Synthesis and biological evaluation of 2-phenylquinolones targeted at Tat/TAR recognition 151
Preferred interaction of D-peptidyl-anthraquinones with double-stranded B-DNA 151
RNA as a drug target 149
DNA-based ligands for Human Cathepsin and medicaments thereof 147
Inhibition of Subgenomic Hepatitis C Virus RNA Replication by Acridone Derivatives: Identification of an NS3 Helicase Inhibitor 147
Sequence specific interaction of drugs interfering with topoisomerase-DNA cleavage complex 146
2,6-di(omega-aminoalkyl)-2,5,6,7-tetrahydropyrazolo[3,4,5-mn]pyrimido[5,6,1-de]-acridine-5,7-diones: Novel, potent, cytotoxic, and DNA-binding agents 145
DNA-Binding Properties of Cytotoxic Naphtindolizinedione-Carboxamides Acting as Type II Topoisomerase Inhibitors. A Combined In Silico and Experimental Study 145
Anti-HIV quinolones: screening of in vitro activity and recognition of viral nucleic acids targets 143
Structure Activity of Topoisomerase I poisons related to Hoechst 33342 143
Perylene side chains modulate G-quadruplex conformation in biologically relevant DNA sequences 142
Substituted 2,5'-Bi-1H-benzimidazoles: topoisomerase I inhibition and cytotoxicity 140
Binding and reactivity towards DNA of PNU-159682, the highly cytotoxic metabolite of nemorubicin 139
A New Beautiful Friendship: Solution Thermal Melting and Nanospray-MS for the Characterization of Intermolecular Conjugates Produced by Bifunctional Crosslinking 138
Further insight into the mechanism of action of quinolones 137
Polyphenolic C-glucosidic ellagitannins present in oak-aged wine inhibit HIV-1 nucleocapsid protein 134
Protoberberine alkaloids and related compounds as dual inhibitors of mammalian topoisomerase I and II 133
Synthesis and DNA Cleavage Activity of Bis-3-chloropiperidines as Alkylating Agents 132
Characterization of the interaction with nucleic acids of the highly cytotoxic oxidative metabolite of the anthracycline nemorubicin by fluorescence quenching assays 130
Aptamer based-microarraysfor protein detection: a potential tool for diagnostic applications 130
Ellagic Acid and Polyhydroxylated Urolithins Are Potent Catalytic Inhibitors of Human Topoisomerase II: An in Vitro Study 130
Aptamer   Microarray   Development   for   Human   Thrombin  Detection:  Interaction  Analysis  in  Solution  and  in  Solid  Phase 126
Pyrroloquinoline derivatives as potential antineoplastic drugs 126
Aminoacyl-anthraquinones: DNA-binding and sequence specificity 123
DNA binding properties and biological activity of novel sequence-selective peptidyl-anthraquinones 122
Identification of topoisomerase I as the cytotoxic target of the protoberberine alkaloid coralyne 120
Totale 20.272
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Categoria #
all - tutte 59.423
article - articoli 51.119
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 900
selected - selezionate 0
volume - volumi 2.080
Totale 113.522
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021265 0 0 0 0 0 0 0 0 0 0 172 93
2021/20221.713 45 218 303 97 56 76 116 181 74 26 227 294
2022/20231.365 279 136 54 142 224 149 35 84 152 15 69 26
2023/2024923 34 91 86 76 82 77 74 57 43 37 128 138
2024/20252.979 100 283 215 191 416 105 163 195 232 112 385 582
2025/20269.816 324 848 1.355 1.627 967 474 1.200 1.042 1.138 651 190 0
Totale 22.822