NANNETTI, GIULIO
NANNETTI, GIULIO
Dipartimento di Medicina Molecolare - DMM
4,6-Diphenylpyridines as Promising Novel Anti-Influenza Agents Targeting the PA-PB1 Protein-Protein Interaction: Structure-Activity Relationships Exploration with the Aid of Molecular Modeling
2016 Trist, Iuni M. L.; Nannetti, Giulio; Tintori, Cristina; Fallacara, Anna Lucia; Deodato, Davide; Mercorelli, Beatrice; Palu', Giorgio; Wijtmans, Maikel; Gospodova, Tzveta; Edink, Ewald; Verheij, Mark; De Esch, Iwan; Viteva, Lilia; Loregian, Arianna; Botta, Maurizio
A Broad anti-influenza hybrid small molecule that potently disrupts the interaction of polymerase acidic protein-basic protein 1 (PA-PB1) subunits
2015 Massari, Serena; Nannetti, Giulio; Desantis, Jenny; Muratore, Giulia; Sabatini, Stefano; Manfroni, Giuseppe; Mercorelli, Beatrice; Cecchetti, Violetta; Palu', Giorgio; Cruciani, Gabriele; Loregian, Arianna; Goracci, Laura; Tabarrini, Oriana
A quantitative LumiFluo assay to test inhibitory compounds blocking p53 degradation induced by human papillomavirus oncoprotein E6 in living cells
2018 Messa, Lorenzo; Celegato, Marta; Bertagnin, Chiara; Mercorelli, Beatrice; Nannetti, Giulio; Palù, Giorgio; Loregian, Arianna
A sensitive and validated HPLC-UV method for the quantitative determination of the new antifungal drug isavuconazole in human plasma
2018 Nannetti, Giulio; Pagni, Silvana; Palù, Giorgio; Loregian, Arianna
Antiviral strategies against influenza virus: towards new therapeutic approaches.
2014 Loregian, Arianna; Mercorelli, Beatrice; Nannetti, Giulio; Compagnin, Chiara; Palu', Giorgio
Corrigendum to “Exploring the cycloheptathiophene-3-carboxamide scaffold to disrupt the interactions of the influenza polymerase subunits and obtain potent anti-influenza activity” [Eur. J. Med. Chem. 138 (2017) 128–139] (S0223523417304610) (10.1016/j.ejmech.2017.06.015))
2018 Desantis, Jenny; Nannetti, Giulio; Massari, Serena; Barreca, Maria Letizia; Manfroni, Giuseppe; Cecchetti, Violetta; Palù, Giorgio; Goracci, Laura; Loregian, Arianna; Tabarrini, Oriana
Daclatasvir plasma level and resistance selection in HIV patients with hepatitis C virus cirrhosis treated with daclatasvir, sofosbuvir, and ribavirin
2016 Parisi, Saverio; Loregian, Arianna; Andreis, Samantha; Nannetti, Giulio; Cavinato, Silvia; Basso, Monica; Scaggiante, Renzo; DAL BELLO, Federico; Messa, Lorenzo; Cattelan, Anna Maria; Palu', Giorgio
Development and validation of a simple and robust HPLC method with UV detection for quantification of the hepatitis C virus inhibitor daclatasvir in human plasma
2017 Nannetti, Giulio; Messa, Lorenzo; Celegato, Marta; Pagni, Silvana; Basso, Monica; Parisi, Saverio G.; Palu', Giorgio; Loregian, Arianna
Development of a simple HPLC-UV method for the determination of the hepatitis C virus inhibitor simeprevir in human plasma
2016 Nannetti, Giulio; Pagni, Silvana; Parisi, Saverio G.; Alberti, Alfredo; Loregian, Arianna; Palu', Giorgio
Drug Repurposing Approach Identifies Inhibitors of the Prototypic Viral Transcription Factor IE2 that Block Human Cytomegalovirus Replication
2016 Mercorelli, Beatrice; Luganini, Anna; Nannetti, Giulio; Tabarrini, Oriana; Palu', Giorgio; Gribaudo, Giorgio; Loregian, Arianna
Efficient and regioselective one-step synthesis of 7-aryl-5-methyl- and 5-aryl-7-methyl-2-amino-[1,2,4]triazolo[1,5-a] pyrimidine derivatives
2017 Massari, Serena; Desantis, Jenny; Nannetti, Giulio; Sabatini, Stefano; Tortorella, Sara; Goracci, Laura; Cecchetti, Violetta; Loregian, Arianna; Tabarrini, Oriana
Exploring the cycloheptathiophene-3-carboxamide scaffold to disrupt the interactions of the influenza polymerase subunits and obtain potent anti-influenza activity
2017 Desantis, Jenny; Nannetti, Giulio; Massari, Serena; Barreca, Maria Letizia; Manfroni, Giuseppe; Cecchetti, Violetta; Palã¹, Giorgio; Goracci, Laura; Loregian, Arianna; Tabarrini, Oriana
Optimization of Small-Molecule Inhibitors of Influenza Virus Polymerase: From Thiophene-3-Carboxamide to Polyamido Scaffolds
2014 Lepri, S; Nannetti, Giulio; Muratore, Giulia; Cruciani, G; Ruzziconi, R; Mercorelli, Beatrice; Palu', Giorgio; Loregian, Arianna; Goracci, L.
Potent and broad-spectrum cycloheptathiophene-3-carboxamide compounds that target the PA-PB1 interaction of influenza virus RNA polymerase and possess a high barrier to drug resistance
2019 Nannetti, Giulio; Massari, Serena; Mercorelli, Beatrice; Bertagnin, Chiara; Desantis, Jenny; Palù, Giorgio; Tabarrini, Oriana; Loregian, Arianna
Structural investigation of cycloheptathiophene-3-carboxamide derivatives targeting influenza virus polymerase assembly.
2013 Massari, S; Nannetti, Giulio; Goracci, L; Sancineto, L; Muratore, Giulia; Sabatini, S; Manfroni, G; Mercorelli, Beatrice; Cecchetti, V; Facchini, M; Palu', Giorgio; Cruciani, G; Loregian, Arianna; Tabarrini, O.
Sviluppo e caratterizzazione di nuovi inibitori diretti contro la polimerasi dei virus dell'influenza di tipo A e B
2014 Nannetti, Giulio
Synthesis and biological evaluation of a library of hybrid derivatives as inhibitors of influenza virus PA-PB1 interaction
2018 D'Agostino, Ilaria; Giacchello, Ilaria; Nannetti, Giulio; Fallacara, Anna Lucia; Deodato, Davide; Musumeci, Francesca; Grossi, Giancarlo; Palù, Giorgio; Cau, Ylenia; Trist, Iuni Margaret; Loregian, Arianna; Schenone, Silvia; Botta, Maurizio
Synthesis and characterization of 1,2,4-triazolo[1,5-a]pyrimidine-2-carboxamide-based compounds targeting the PA-PB1 interface of influenza A virus polymerase
2021 Massari, S.; Bertagnin, C.; Pismataro, M. C.; Donnadio, A.; Nannetti, G.; Felicetti, T.; Di Bona, S.; Nizi, M. G.; Tensi, L.; Manfroni, G.; Loza, M. I.; Sabatini, S.; Cecchetti, V.; Brea, J.; Goracci, L.; Loregian, A.; Tabarrini, O.