Vernal keratoconjunctivitis (VKC) is a severe ocular allergy with pathogenic mechanism poorly understood and no efficacious treatment. The aims of the study were to determine quantities and distribution of Hsp-chaperones in the conjunctiva of VKC patients and assess their levels in conjunctival epithelial and fibroblast cultures exposed to inflammatory stimuli.
Chaperone patterns in vernal keratoconjunctivitis are distinctive of cell and Hsp type, and are modified by inflammatory stimuli
LEONARDI, ANDREA;TARRICONE, ELENA;CORRAO, SIMONA;ALAIBAC, MAURO SALVATORE ALESSANDRO;CORSO, ALAIN JODY;ZAVAN, BARBARA;VENIER, PAOLA;BRUN, PAOLA
2016
Abstract
Vernal keratoconjunctivitis (VKC) is a severe ocular allergy with pathogenic mechanism poorly understood and no efficacious treatment. The aims of the study were to determine quantities and distribution of Hsp-chaperones in the conjunctiva of VKC patients and assess their levels in conjunctival epithelial and fibroblast cultures exposed to inflammatory stimuli.
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