SPERIMENTAL EVALUATION OF PERI IMPLANT AFFECTIONS TREATMENT USING GLICYNE POWDER

Introduction:The main cause of failure of implant therapy is represented by peri-implantitis.Peri-implantitis is an infection of the tissue around an implant, resulting in the loss of supporting bone. Risk factors for peri-implantitis consist of a history of periodontitis, dental plaque, poor oral hygiene, smoking, alcohol consumption and diabetes. A clinical diagnosis indicates inflammatory signs including bleeding on probing with or without suppuration and a peri-implant pocket depth ≥5mm. The purpose of this study is to evaluate the effectiveness of the use of glycine in the treatment of the peri-implantitis. Materials and method:In this study were evaluated 24 patients (67% females, 33% males) with age ranging from 45 to75 year for a total of 96 patients, presenting a clinical periimplantitis diagnosis. The inclusion criteria were: presence of periimplantitis in at least one implant site; bleeding on probing with periimplant pocket depth ranging from 4 to 8 millimeters.The glycin powder (25µm)was dispensed trought the periimplant furrow with the aid of Air-flow Perio device.Each patient was inserted in a treating plan which set for 4 treatments in a progressive time distance. First visit, Time 0 (baseline); Second visit:after 1 month by the first; Third visit, after 2 months by the first; and the Fourth after 3 months.In each visit were detected: periimplant probings, bleeding index (BoP), O' Learly plaque index before the start of the tratment and after the end of the treatment and mesurements of the keratinized gengiva and for the gingival recession. Wilcoxon sum rank test and Bernoulli estimation were used to evaluate the therapeutic efficiency of glycine powder. Results:Using the Wilcoxon sum rank test the comparative statistic evaluated the efficiency of glycine powder by the depht of pathological probings of the periimplants parodontal pockets (p-value<0.001) and the inflammatory spots of periimplant tissues (p-value<0.001).The Bernoulli estimation evaluated that the periimplant tissues V=(p(VY) [0,689; 0,874]) = 0,95.In the 90% of the cases have been registered a complete healing, and in the remaining 10% were obtained a partial healing, but still statistically significative. Conclusion:The glycine powder treatment perio delivered within the periimplant furrow have proven to be statistically effective to be marked as effective periimplantitis terapy, and will not modify the implant surface.