The synthesis of 2H-benzopyrano[7,8-b][1,4]tetrahydrobenzodioxin-2-ones and 2H-benzopyrano[7,8-b][1,4]benzodioxin-2-ones is reported. This class of compounds, prepared with the aim of obtaining new monofunctional photosensitizing drug, appears to be ineffective upon UVA irradiation but shows a moderate but significant activity in the dark.
Synthesis and biological properties of some 2H-1-benzopyran [7,8-b][1,4]benzodioxin-2-ones.
BACCICHETTI, FRANCAROSA;CHILIN, ADRIANA;GUIOTTO, ADRIANO;MARZANO, CRISTINA;CARLASSARE, FRANCESCO;BORDIN, FRANCO
1997
Abstract
The synthesis of 2H-benzopyrano[7,8-b][1,4]tetrahydrobenzodioxin-2-ones and 2H-benzopyrano[7,8-b][1,4]benzodioxin-2-ones is reported. This class of compounds, prepared with the aim of obtaining new monofunctional photosensitizing drug, appears to be ineffective upon UVA irradiation but shows a moderate but significant activity in the dark.
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