The stabilizing action of C(α)-tetrasubstituted α-amino acids inserted into a sequence of short peptides allowed for the first time the preparation of water-soluble nanoparticles of different materials coated with a helix-structured undecapeptide. This peptide coating strongly favors nanoparticle uptake by human immune system cells.
Water-soluble peptide-coated nanoparticles: Control of the helix structure and enhanced differential binding to immune cells
TAVANO, REGINA;CAUSIN, VALERIO;PAPINI, EMANUELE;MANCIN, FABRIZIO;MORETTO, ALESSANDRO
2011
Abstract
The stabilizing action of C(α)-tetrasubstituted α-amino acids inserted into a sequence of short peptides allowed for the first time the preparation of water-soluble nanoparticles of different materials coated with a helix-structured undecapeptide. This peptide coating strongly favors nanoparticle uptake by human immune system cells.
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