MALFACINI, DAVIDE
MALFACINI, DAVIDE
Dipartimento di Scienze del Farmaco - DSF
Activation of peripheral NOP receptors reduces periorbital mechanical allodynia evoked by CGRP in mice
2025 Sturaro, C.; Pola, P.; Argentieri, M.; Frezza, A.; Marini, M.; De Logu, F.; Albanese, V.; Soukupova, M.; Malfacini, D.; Zaveri, N. T.; Nassini, R.; Jensen, D. D.; Geppetti, P.; Calo', G.; Ruzza, C.
In vitro and in vivo study of butyrylfentanyl and 4-fluorobutyrylfentanyl in female and male mice: Role of the CRF1 receptor in cardiorespiratory impairment
2025 Bilel, Sabrine; Azevedo Neto, Joaquim; Tirri, Micaela; Corli, Giorgia; Bassi, Marta; Fantinati, Anna; Serpelloni, Giovanni; Malfacini, Davide; Trapella, Claudio; Calo', Girolamo; Marti, Matteo
In vitro pharmacological evaluation of the novel NOP receptor partial agonist sunobinop
2025 Camilotto, Riccardo; Malfacini, Davide; Pola, Pietro; Morrone, Erika; Frezza, Alessia; Ramalingam, Rahul; Sturaro, Chiara; Pacifico, Salvatore; Ruzza, Chiara; Guerrini, Remo; Whiteside, Garth; Calo', Girolamo
A Multi-Angle Approach to Predict Peptide-GPCR Complexes: The N/OFQ-NOP System as a Successful AlphaFold Application Case Study
2024 Ciancetta, Antonella; Malfacini, Davide; Gozzi, Matteo; Marzola, Erika; Camilotto, Riccardo; Calo', Girolamo; Guerrini, Remo
In vitro pharmacological characterization of growth hormone secretagogue receptor ligands using the dynamic mass redistribution and calcium mobilization assays
2024 Sturaro, Chiara; Ruzza, Chiara; Ferrari, Federica; Pola, Pietro; Argentieri, Michela; Frezza, Alessia; Marzola, Erika; Bettegazzi, Barbara; Cattaneo, Stefano; Pietra, Claudio; Malfacini, Davide; Calo', Girolamo
Probing non-peptide agonists binding at the human nociceptin/orphanin FQ receptor: a molecular modelling study
2024 Gozzi, Matteo; Malfacini, Davide; Albanese, Valentina; Pacifico, Salvatore; Preti, Delia; Guerrini, Remo; Calo', Girolamo; Ciancetta, Antonella
(L)-Monomethyl Tyrosine (Mmt): New Synthetic Strategy via Bulky 'Forced-Traceless' Regioselective Pd-Catalyzed C(sp2)-H Activation
2023 Illuminati, Davide; Trapella, Claudio; Zanirato, Vinicio; Guerrini, Remo; Albanese, Valentina; Sturaro, Chiara; Stragapede, Simona; Malfacini, Davide; Compagnin, Greta; Catani, Martina; Fantinati, Anna
Functional selectivity of EM-2 analogs at the mu-opioid receptor
2023 Piekielna-Ciesielska, Justyna; Malfacini, Davide; Djeujo, Francine Medjiofack; Marconato, Chantal; Wtorek, Karol; Calo', Girolamo; Janecka, Anna
GPCR in Adipose Tissue Function-Focus on Lipolysis
2023 Malfacini, Davide; Pfeifer, Alexander
The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors
2023 Alexander, Stephen P. H.; Christopoulos, Arthur; Davenport, Anthony P.; Kelly, Eamonn; Mathie, Alistair A.; Peters, John A.; Veale, Emma L.; Armstrong, Jane F.; Faccenda, Elena; Harding, Simon D.; Davies, Jamie A.; Abbracchio, Maria Pia; Abraham, George; Agoulnik, Alexander; Alexander, Wayne; Al‐hosaini, Khaled; Bäck, Magnus; Baker, Jillian G.; Barnes, Nicholas M.; Bathgate, Ross; Beaulieu, Jean‐martin; Beck‐sickinger, Annette G.; Behrens, Maik; Bernstein, Kenneth E.; Bettler, Bernhard; Birdsall, Nigel J. M.; Blaho, Victoria; Boulay, Francois; Bousquet, Corinne; Bräuner‐osborne, Hans; Burnstock, Geoffrey; Calo', Girolamo; Castaño, Justo P.; Catt, Kevin J.; Ceruti, Stefania; Chazot, Paul; Chiang, Nan; Chini, Bice; Chun, Jerold; Cianciulli, Antonia; Civelli, Olivier; Clapp, Lucie H.; Couture, Réjean; Cox, Helen M.; Csaba, Zsolt; Dahlgren, Claes; Dent, Gordon; Douglas, Steven D.; Dournaud, Pascal; Eguchi, Satoru; Escher, Emanuel; Filardo, Edward J.; Fong, Tung; Fumagalli, Marta; Gainetdinov, Raul R.; Garelja, Michael L.; de Gasparo, Marc; Gerard, Craig; Gershengorn, Marvin; Gobeil, Fernand; Goodfriend, Theodore L.; Goudet, Cyril; Grätz, Lukas; Gregory, Karen J.; Gundlach, Andrew L.; Hamann, Jörg; Hanson, Julien; Hauger, Richard L.; Hay, Debbie L.; Heinemann, Akos; Herr, Deron; Hollenberg, Morley D.; Holliday, Nicholas D.; Horiuchi, Mastgugu; Hoyer, Daniel; Hunyady, László; Husain, Ahsan; Ijzerman, Adriaan P.; Inagami, Tadashi; Jacobson, Kenneth A.; Jensen, Robert T.; Jockers, Ralf; Jonnalagadda, Deepa; Karnik, Sadashiva; Kaupmann, Klemens; Kemp, Jacqueline; Kennedy, Charles; Kihara, Yasuyuki; Kitazawa, Takio; Kozielewicz, Pawel; Kreienkamp, Hans‐jürgen; Kukkonen, Jyrki P.; Langenhan, Tobias; Larhammar, Dan; Leach, Katie; Lecca, Davide; Lee, John D.; Leeman, Susan E.; Leprince, Jérôme; Li, Xaria X.; Lolait, Stephen J.; Lupp, Amelie; Macrae, Robyn; Maguire, Janet; Malfacini, Davide; Mazella, Jean; Mcardle, Craig A.; Melmed, Shlomo; Michel, Martin C.; Miller, Laurence J.; Mitolo, Vincenzo; Mouillac, Bernard; Müller, Christa E.; Murphy, Philip M.; Nahon, Jean‐louis; Ngo, Tony; Norel, Xavier; Nyimanu, Duuamene; O’Carroll, Anne‐marie; Offermanns, Stefan; Panaro, Maria Antonietta; Parmentier, Marc; Pertwee, Roger G.; Pin, Jean‐philippe; Prossnitz, Eric R.; Quinn, Mark; Ramachandran, Rithwik; Ray, Manisha; Reinscheid, Rainer K.; Rondard, Philippe; Rovati, G. Enrico; Ruzza, Chiara; Sanger, Gareth J.; Schöneberg, Torsten; Schulte, Gunnar; Schulz, Stefan; Segaloff, Deborah L.; Serhan, Charles N.; Singh, Khuraijam Dhanachandra; Smith, Craig M.; Stoddart, Leigh A.; Sugimoto, Yukihiko; Summers, Roger; Tan, Valerie P.; Thal, David; Thomas, Walter ( Wally); Timmermans, Pieter B. M. W. M.; Tirupula, Kalyan; Toll, Lawrence; Tulipano, Giovanni; Unal, Hamiyet; Unger, Thomas; Valant, Celine; Vanderheyden, Patrick; Vaudry, David; Vaudry, Hubert; Vilardaga, Jean‐pierre; Walker, Christopher S.; Wang, Ji Ming; Ward, Donald T.; Wester, Hans‐jürgen; Willars, Gary B.; Williams, Tom Lloyd; Woodruff, Trent M.; Yao, Chengcan; Ye, Richard D.
In vitro and in vivo pharmaco-dynamic study of the novel fentanyl derivatives: Acrylfentanyl, Ocfentanyl and Furanylfentanyl
2022 Bilel, S.; Azevedo Neto, J.; Arfe, R.; Tirri, M.; Gaudio, R. M.; Fantinati, A.; Bernardi, T.; Boccuto, F.; Marchetti, B.; Corli, G.; Serpelloni, G.; De-Giorgio, F.; Malfacini, D.; Trapella, C.; Calo', G.; Marti, M.
Pharmacology of Kappa Opioid Receptors: Novel Assays and Ligands
2022 Sturaro, Chiara; Malfacini, Davide; Argentieri, Michela; Medjiofack Djeujo, Francine; Marzola, Erika; Albanese, Valentina; Ruzza, Chiara; Guerrini, Remo; Calo’, Girolamo; Molinari, Paola
Functional Selectivity Does Not Predict Antinociceptive/Locomotor Impairing Potencies of NOP Receptor Agonists
2021 Azevedo Neto, Joaquim; Ruzza, Chiara; Sturaro, Chiara; Malfacini, Davide; Pacifico, Salvatore; Zaveri, Nurulain T.; Calò, Girolamo
Novel Mixed NOP/Opioid Receptor Peptide Agonists
2021 Pacifico, S.; Albanese, V.; Illuminati, D.; Marzola, E.; Fabbri, M.; Ferrari, F.; Holanda, V. A. D.; Sturaro, C.; Malfacini, D.; Ruzza, C.; Trapella, C.; Preti, D.; Lo Cascio, E.; Arcovito, A.; Della Longa, S.; Marangoni, M.; Fattori, D.; Nassini, R.; Calo', G.; Guerrini, R.
Pharmacological characterization of naloxegol: In vitro and in vivo studies
2021 Costanzini, Anna; Ruzza, Chiara; Neto, Joaquim Azevedo; Sturaro, Chiara; Malfacini, Davide; Sternini, Catia; De Giorgio, Roberto; Calò, Girolamo
Unraveling binding mechanism and kinetics of macrocyclic Gαq protein inhibitors
2021 Voss, J. H.; Nagel, J.; Rafehi, M.; Guixa-Gonzalez, R.; Malfacini, D.; Patt, J.; Kehraus, S.; Inoue, A.; Konig, G. M.; Kostenis, E.; Deupi, X.; Namasivayam, V.; Muller, C. E.
Pharmacological Assays for Investigating the NOP Receptor
2019 Malfacini, Davide; Calo', Girolamo
Rational design of a heterotrimeric G protein subunit with artificial inhibitor sensitivity
2019 Malfacini, D.; Patt, J.; Annala, S.; Harpsoe, K.; Eryilmaz, F.; Reher, R.; Crusemann, M.; Hanke, W.; Zhang, H.; Tietze, D.; Gloriam, D. E.; Brauner-Osborne, H.; Stromgaard, K.; Konig, G. M.; Inoue, A.; Gomeza, J.; Kostenis, E.
Heterologous Expression, Biosynthetic Studies, and Ecological Function of the Selective Gq-Signaling Inhibitor FR900359
2018 Crusemann, M.; Reher, R.; Schamari, I.; Brachmann, A. O.; Ohbayashi, T.; Kuschak, M.; Malfacini, D.; Seidinger, A.; Pinto-Carbo, M.; Richarz, R.; Reuter, T.; Kehraus, S.; Hallab, A.; Attwood, M.; Schioth, H. B.; Mergaert, P.; Kikuchi, Y.; Schaberle, T. F.; Kostenis, E.; Wenzel, D.; Muller, C. E.; Piel, J.; Carlier, A.; Eberl, L.; Konig, G. M.
Lack of beta-arrestin signaling in the absence of active G proteins
2018 Grundmann, M.; Merten, N.; Malfacini, D.; Inoue, A.; Preis, P.; Simon, K.; Ruttiger, N.; Ziegler, N.; Benkel, T.; Schmitt, N. K.; Ishida, S.; Muller, I.; Reher, R.; Kawakami, K.; Inoue, A.; Rick, U.; Kuhl, T.; Imhof, D.; Aoki, J.; Konig, G. M.; Hoffmann, C.; Gomeza, J.; Wess, J.; Kostenis, E.