GIORGIO, MARCO
 Distribuzione geografica
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Continente #
NA - Nord America 6.286
AS - Asia 1.126
EU - Europa 431
OC - Oceania 3
AF - Africa 1
SA - Sud America 1
Totale 7.848
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Nazione #
US - Stati Uniti d'America 6.284
CN - Cina 674
SG - Singapore 256
VN - Vietnam 172
IT - Italia 116
FI - Finlandia 89
SE - Svezia 47
DE - Germania 43
GB - Regno Unito 37
FR - Francia 34
UA - Ucraina 24
IE - Irlanda 14
IN - India 12
NL - Olanda 9
RU - Federazione Russa 7
AE - Emirati Arabi Uniti 5
CZ - Repubblica Ceca 3
AT - Austria 2
CA - Canada 2
HK - Hong Kong 2
NZ - Nuova Zelanda 2
TR - Turchia 2
AU - Australia 1
BR - Brasile 1
DK - Danimarca 1
EG - Egitto 1
ES - Italia 1
IR - Iran 1
JO - Giordania 1
JP - Giappone 1
LT - Lituania 1
NO - Norvegia 1
PL - Polonia 1
RO - Romania 1
Totale 7.848
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Città #
Fairfield 1.445
Woodbridge 671
Ashburn 579
Houston 518
Cambridge 501
Seattle 491
Wilmington 373
Ann Arbor 247
Singapore 190
Boardman 189
Chandler 188
Dong Ket 172
Beijing 165
Princeton 153
Medford 133
San Diego 131
Des Moines 108
Nanjing 94
Jacksonville 69
Helsinki 65
Jinan 58
Roxbury 55
Santa Clara 54
Shenyang 44
Padova 31
Nanchang 26
Hebei 25
Ningbo 24
Hefei 20
Zhengzhou 20
Guangzhou 19
Changsha 17
Dublin 14
London 13
Dearborn 12
Lanzhou 12
Tianjin 11
Kharkiv 10
Milan 10
Pune 10
Haikou 9
Jiaxing 9
Taiyuan 9
Redwood City 7
Rome 7
Shanghai 7
Sommacampagna 7
Borås 6
Fuzhou 6
Hangzhou 6
Kilburn 6
Norwalk 6
Dubai 5
Kunming 5
Lappeenranta 5
Selvazzano Dentro 5
Parma 4
Barzago 3
Chengdu 3
Chiswick 3
Chongqing 3
Ogden 3
Paese 3
Revere 3
Urbino 3
Washington 3
Atrani 2
Castel San Pietro Terme 2
Chicago 2
Frankfurt am Main 2
Hong Kong 2
Hounslow 2
Hradec Králové 2
Indiana 2
Istanbul 2
Munich 2
New Bedfont 2
Paris 2
Shaoxing 2
Southwark 2
Springfield 2
Taizhou 2
Vienna 2
Wuhan 2
Xian 2
Amman 1
Amsterdam 1
Bengaluru 1
Bergamo 1
Brno 1
Brooklyn 1
Calcinate 1
Castegnero 1
Castel Maggiore 1
Chiaravalle 1
Clifton 1
Council Bluffs 1
Dallas 1
Dongguan 1
Geislingen an der Steige 1
Totale 7.156
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Nome #
Diabetes-associated myelopoiesis drives stem cell mobilopathy through an OSM-p66Shc signaling pathway 162
1. Novel neuroferritinopathy mouse model (ftl 498instc) shows progressive brain iron dysregulation, morphological signs of early neurodegeneration and motor coordination deficits 158
p66Shc deletion or deficiency protects from obesity but not metabolic dysfunction in mice and humans 143
Diabetes causes bone marrow autonomic neuropathy and impairs stem cell mobilization via dysregulated p66Shc and Sirt1 129
The cellular prion protein counteracts cardiac oxidative stress 125
Electron transfer between cytochrome c and p66Shc generates reactive oxygen species that trigger mitochondrial apoptosis 117
The p66(Shc) redox adaptor protein is induced by saturated fatty acids and mediates lipotoxicity-induced apoptosis in pancreatic beta cells. 117
The p66ShcA adaptor protein regulates healing after myocardial infarction 113
New aspects of p66Shc in ischaemia reperfusion injury and other cardiovascular diseases 110
Interplay among H3K9-editing enzymes SUV39H1, JMJD2C and SRC-1 drives p66 Shc transcription and vascular oxidative stress in obesity 109
p66(Shc)-generated Oxidative Signal Promotes Fat Accumulation 107
Ablation of the gene encoding p66(Shc) protects mice against AGE-induced glomerulopathy by preventing oxidant-dependent tissue injury and further AGE accumulation 107
The Redox Enzyme p66Shc Contributes to Diabetes and Ischemia-Induced Delay in Cutaneous Wound Healing 105
The p53-p66Shc apoptotic pathway is dispensable for tumor suppression whereas the p66Shc-generated oxidative stress initiates tumorigenesis. 105
A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis 102
Sustained hippocampal neurogenesis in females is amplified in P66(Shc-/-) mice: An animal model of healthy aging 95
Therapeutic synergy between tigecycline and venetoclax in a preclinical model of MYC/BCL2 double-hit B cell lymphoma 93
Apoptosis and aging: Role of p66(Shc) Redox protein 87
The cardioprotective effects elicited by p66(Shc) ablation demonstrate the crucial role of mitochondrial ROS formation in ischemia/reperfusion injury 86
Angiogenesis inhibition by the maleimide-based small molecule GNX-686 86
Medullary thyroid carcinomas in transgenic mice expressing a polyoma carboxyl-terminal truncated middle-T and wild type small-T antigens 86
Blood orange juice inhibits fat accumulation in mice 85
Protein kinase C beta and prolyl isomerase 1 regulate mitochondrial effects of the life-span determinant p66(Shc) 84
Enrichment of tomato fruit with health-promoting anthocyanins by expression of select transcription factors 84
Null Mutations at the p66 and Bradykinin 2 Receptor Loci Induce Divergent Phenotypes in the Diabetic Kidney 84
Circulating Cytochrome c as Potential Biomarker of Impaired Reperfusion in ST-Segment Elevation Acute Myocardial Infarction 83
Mitochondrial redox signalling by p66Shc mediates ALS-like disease through Rac1 inactivation 83
Deletion of p66(Shc) longevity gene protects against experimental diabetic glomerulopathy by preventing diabetes-induced oxidative stress 83
Mitochondrial pathways for ROS formation and myocardial injury: the relevance of p66(Shc) and monoamine oxidase 82
Gene rearrangements in the molecular pathogenesis of acute promyelocytic leukemia 82
The Shc locus regulates insulin signaling and adiposity in mammals 81
Alternative Forms and Functions of the c-kit Receptor and Its Ligand During Spermatogenesis 81
p66Shc Deletion Confers Vascular Protection in Advanced Atherosclerosis in Hypercholesterolemic Apolipoprotein E Knockout Mice 81
Electrochemical study of hydrogen peroxide formation in isolated mitochondria 81
Greater resistance to inflammation at adulthood could contribute to extended life span of p66(Shc-/-) mice 80
Moro orange juice prevents fatty liver in mice 80
Deletion of the life span determinant p66(Shc) prevents age-dependent increases in emotionality and pain sensitivity in mice 79
The life span determinant p66Shc localizes to mitochondria where it associates with mitochondrial heat shock protein 70 and regulates trans-membrane potential 79
p66(ShcA) modulates tissue response to hindlimb ischemia 78
Decreased Superoxide Production in Macrophages of Long-lived p66Shc Knock-out Mice 78
Hydrogen peroxide: a metabolic by-product or a common mediator of ageing signals? 78
Deletion of the p66(Shc) longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet 78
Deletion of the lifespan determinant p66(Shc) improves performance in a spatial memory task, decreases levels of oxidative stress markers in the hippocampus and increases levels of the neurotrophin BDNF in adult mice 77
Genetic inactivation of the p66 isoform of ShcA is neuroprotective in a murine model of multiple sclerosis 76
Hematopoietic and Nonhematopoietic p66Shc Differentially Regulates Stem Cell Traffic and Vascular Response to Ischemia in Diabetes 73
Microdrawing and highlighting a reactive surface 72
Mitochondria and vascular pathology 71
Regulatory effects of the mitochondrial energetic status on mitochondrial p66(Shc) 71
Mitochondrial DNA copy number is regulated by cellular proliferation: A role for Ras and p66 (Shc) 70
Electrochemical Detection of H2O2 Formation in Isolated Mitochondria. 66
Phosphorylation of p66Shc Downregulates PMCA4a and Sensitizes T Cells to Ca2+ Deregulation, Mitochondrial Dysfunction and Apoptosis 64
Cyclophilin D counteracts P53-mediated growth arrest and promotes Ras tumorigenesis. 62
In S. cerevisiae hydroxycitric acid antagonizes chronological aging and apoptosis regardless of citrate lyase 62
Oxidative stress and the unfulfilled promises of antioxidant agents 62
Cyanidin-3-O-β-glucoside and protocatechuic acid activate AMPK/mTOR/S6K pathway and improve glucose homeostasis in mice 61
Modelling the p53/p66Shc aging pathway in the shortest living vertebrate Nothobranchius Furzeri 60
Genetic ablation of p66(Shc) rescues functional and morphological abnormalities in collagen VI dystrophic mice 57
The Influence of Shc Proteins on Life Span in Mice 57
P66SHC deletion improves fertility and progeric phenotype of late-generation TERC-deficient mice but not their short lifespan 57
The Determining Role of Mitochondrial Reactive Oxygen Species Generation and Monoamine Oxidase Activity in Doxorubicin-Induced Cardiotoxicity 57
New aspects of p66Shc in ischemia reperfusion injury and cardiovascular diseases 56
SATURATION MUTAGENESIS OF THE HUMAN INTERLEUKIN-6 RECEPTOR-BINDING SITE - IMPLICATIONS FOR ITS 3-DIMENSIONAL STRUCTURE 55
Glucose and Lactate Miniaturized Biosensors for SECM-Based High-Spatial Resolution Analysis: A Comparative Study 55
Novel insights into the PKCβ-dependent regulation of the oxidoreductase p66Shc 54
Inhibition of monoamine oxidases reduces doxorubicin-induced cardiomyocyte death 53
The p66Shc knocked out mice are short lived under natural condition 52
Scanning electro-chemical microscopy reveals cancer cell redox state 52
Isolation stress affects tumor progression through a BDNF-neuroendocrine axis in a mouse model of breast cancer 51
Maternal care determinant of longevity? 51
p66(shc) and oxidative stress induced by post-ischemic reperfusion injury 50
On the epigenetic role of guanosine oxidation 49
Inhibition of the Histone Demethylase LSD1 Combined with Caloric Restriction or IGF1/Insulin Inhibition Leads to Durable Responses in a Preclinical Model of Acute Myeloid Leukemia 46
Epigenomic profiling of archived FFPE tissues by enhanced PAT-ChIP (EPAT-ChIP) technology 46
Dietary cyanidin 3-glucoside from purple corn ameliorates doxorubicin-induced cardiotoxicity in mice 46
THE OXIDATIVE STRESS RESPONSE GENE P66 SHC AND THE TUMOR SUPPRESSOR GENE P53 INDUCE MITOCHONDRIAL DNA DAMAGES 45
Ras-dependent carbon metabolism and transformation in mouse broblasts 44
The P66Shc/Mitochondrial Permeability Transition Pore Pathway Determines Neurodegeneration 44
Oxidative stress activates a specific p53 transcriptional response that regulates cellular senescence and aging 44
Low oxygen tension maintains multipotency, whereas normoxia increases differentiation of mouse bone marrow stromal cells 44
The mitochondrial translation machinery as a therapeutic target in Myc-driven lymphomas 44
Deletion of the redox enzyme p66shc promotes diabetic wound healing in mice 42
DEVELOPMENT OF PROGRESSIVE KIDNEY DAMAGE AND MYELOMA KIDNEY IN INTERLEUKIN-6 TRANSGENIC MICE 42
Cardiac Stem Cells and the Diabetic Cardiomyopathy 42
Mouse models and Longevity 41
null 41
The Other Face of ROS: a Driver of Stem Cell Expansion in Colorectal Cancer. 40
Diabetes promotes cardiac stem cell aging and heart failure, which are prevented by deletion of the p66(shc) gene 40
Insights into the beneficial effect of caloric/ dietary restriction for a healthy and prolonged life 39
Deletion of p66Shc in mice increases the frequency of size-change mutations in the lacZ transgene 39
A PROMOTER WITHIN AN INTRON OF THE MOUSE C-KIT RECEPTOR GENE, DRIVES THE TRANSCRIPTION OF A TRUNCATED FORM OF THE RECEPTOR IN LATE SPERMIOGENESIS 39
Metabolic Constrains Rule Metastasis Progression 39
P66(Shc), redox signaling and aging 37
Comparative analysis of histone h3k4me3 distribution in mouse liver in different diets reveals the epigenetic efficacy of cyanidin-3-o-glucoside dietary intake 37
P66ShcA adaptor protein facilitates heart rupture via activation of MMP-2 in an in vivo model of myocardial infarction in mice 36
Crucial role of p66ShcA in tissue damage induced by hindlimb ischaemia 36
A Role for PML in Innate Immunity 35
A cell- and developmental stage-specific promoter drives the expression of a truncated c-kit protein during mouse spermatid elongation 33
RECOGNITION EFFICIENCY OF THE HEPATITIS-B VIRUS POLYADENYLATION SIGNALS IS TISSUE SPECIFIC IN TRANSGENIC MICE 33
6. PROBING OXYGEN METABOLISM IN TUMOUR AND NORMAL LIVING CELLS BY SCANNING ELECTROCHEMICAL MICROSCOPY. 33
Histone H3 Lysine 4 and 27 Trimethylation Landscape of Human Alzheimer’s Disease 33
Totale 6.959
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Categoria #
all - tutte 34.888
article - articoli 33.433
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 188
selected - selezionate 0
volume - volumi 897
Totale 69.406
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.514 0 0 0 0 0 0 258 284 323 340 233 76
2020/20211.641 154 124 183 47 33 71 43 179 193 189 163 262
2021/20221.605 43 201 181 116 64 51 82 157 86 42 217 365
2022/2023634 254 33 25 50 82 63 5 27 47 9 28 11
2023/2024459 6 28 30 36 21 47 55 39 14 16 79 88
2024/2025490 10 87 57 37 250 48 1 0 0 0 0 0
Totale 8.013