A Ketogenic Diet (KD) that improves memory in aged C57BL/6 mice is tested in APP/PS1 Alzheimer’s mice. Seven months KD rescues Long-Term-Potentiation to wild-type levels, as does a one-hour soak with 3 mM Betahydroxybutyrate. KD increases synaptic pathways but does not alter Aβ amyloid.

Ketogenic diet and BHB rescue the fall of long-term potentiation in an Alzheimer’s mouse model and stimulates synaptic plasticity pathway enzymes

Persico G.;Giorgio M.;
2024

Abstract

A Ketogenic Diet (KD) that improves memory in aged C57BL/6 mice is tested in APP/PS1 Alzheimer’s mice. Seven months KD rescues Long-Term-Potentiation to wild-type levels, as does a one-hour soak with 3 mM Betahydroxybutyrate. KD increases synaptic pathways but does not alter Aβ amyloid.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11577/3516672
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