BORTOLOZZI, ROBERTA
 Distribuzione geografica
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Continente #
NA - Nord America 6.594
AS - Asia 4.105
EU - Europa 1.801
SA - Sud America 628
AF - Africa 578
Continente sconosciuto - Info sul continente non disponibili 144
OC - Oceania 78
Totale 13.928
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Nazione #
US - Stati Uniti d'America 6.233
SG - Singapore 1.260
CN - Cina 884
VN - Vietnam 504
HK - Hong Kong 497
IT - Italia 456
BR - Brasile 383
DE - Germania 174
FI - Finlandia 168
FR - Francia 134
BD - Bangladesh 129
IN - India 113
PL - Polonia 112
GB - Regno Unito 83
JP - Giappone 77
RU - Federazione Russa 77
NL - Olanda 71
CA - Canada 58
IQ - Iraq 49
AR - Argentina 48
PK - Pakistan 47
SE - Svezia 45
TR - Turchia 45
MX - Messico 38
SA - Arabia Saudita 36
BJ - Benin 35
JM - Giamaica 35
ID - Indonesia 34
UA - Ucraina 34
ES - Italia 33
KR - Corea 32
CO - Colombia 31
PH - Filippine 31
IE - Irlanda 30
ZA - Sudafrica 30
TH - Thailandia 26
VE - Venezuela 26
MY - Malesia 25
KE - Kenya 24
AT - Austria 23
BY - Bielorussia 23
CL - Cile 23
EE - Estonia 23
ET - Etiopia 23
PY - Paraguay 23
EC - Ecuador 22
JO - Giordania 22
AZ - Azerbaigian 20
CH - Svizzera 20
CV - Capo Verde 20
EG - Egitto 20
PE - Perù 20
PS - Palestinian Territory 20
RO - Romania 20
AL - Albania 19
BO - Bolivia 19
GF - Guiana Francese 19
HN - Honduras 19
KG - Kirghizistan 19
MR - Mauritania 19
AO - Angola 18
MU - Mauritius 18
MZ - Mozambico 18
TJ - Tagikistan 18
TT - Trinidad e Tobago 18
CR - Costa Rica 17
GT - Guatemala 17
MK - Macedonia 17
ML - Mali 17
NI - Nicaragua 17
PR - Porto Rico 17
SN - Senegal 17
TW - Taiwan 17
UZ - Uzbekistan 17
ZW - Zimbabwe 17
CI - Costa d'Avorio 16
CM - Camerun 16
CW - ???statistics.table.value.countryCode.CW??? 16
CZ - Repubblica Ceca 16
NC - Nuova Caledonia 16
AU - Australia 15
BG - Bulgaria 15
DK - Danimarca 15
HU - Ungheria 15
LV - Lettonia 15
NZ - Nuova Zelanda 15
PT - Portogallo 15
SI - Slovenia 15
TN - Tunisia 15
TZ - Tanzania 15
AE - Emirati Arabi Uniti 14
BA - Bosnia-Erzegovina 14
GA - Gabon 14
GH - Ghana 14
IL - Israele 14
PF - Polinesia Francese 14
UG - Uganda 14
AF - Afghanistan, Repubblica islamica di 13
DO - Repubblica Dominicana 13
GP - Guadalupe 13
Totale 13.210
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Città #
Ashburn 834
Singapore 760
Fairfield 696
San Jose 607
Hong Kong 451
Houston 352
Woodbridge 352
Seattle 296
Cambridge 269
Ann Arbor 231
Wilmington 230
Chandler 222
Beijing 193
Santa Clara 172
Los Angeles 140
Ho Chi Minh City 129
Hanoi 116
Helsinki 93
Boardman 90
San Diego 90
Princeton 69
Bytom 66
Medford 61
Lauterbourg 59
Padova 57
Munich 55
Des Moines 53
Tokyo 52
Dallas 50
Roxbury 50
New York 49
Council Bluffs 47
Hefei 46
Chicago 37
Guangzhou 34
Rome 34
Cotonou 32
Nanjing 32
Orem 32
Da Nang 31
Milan 31
Turku 30
Warsaw 30
São Paulo 29
Buffalo 27
Seoul 24
Montreal 23
Amman 22
Dublin 22
London 22
Nairobi 22
The Dalles 22
Haiphong 21
Tianjin 21
Baghdad 20
Shenyang 20
Dong Ket 19
Lahore 19
Padua 19
Tallinn 19
Baku 18
Kingston 18
Shanghai 18
Brooklyn 17
Dushanbe 17
Frankfurt am Main 17
Johannesburg 17
Luanda 17
Managua 17
Praia 17
Tashkent 17
Abidjan 16
Dakar 16
Denver 16
Harare 16
Lappeenranta 16
Maputo 16
Noumea 16
Vienna 16
Bamako 15
Bishkek 15
Chennai 15
Minsk 15
Nouakchott 15
Addis Ababa 14
Dar es Salaam 14
Kampala 14
Stockholm 14
Accra 13
Jeddah 13
Jinan 13
Libreville 13
Papeete 13
Riga 13
Riyadh 13
San José 13
Santiago 13
Hebei 12
Kuala Lumpur 12
Nassau 12
Totale 8.333
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Nome #
Evaluating the effects of fluorine on biological properties and metabolic stability of some antitubulin 3-substituted 7-phenyl-pyrroloquinolinones 378
Synthesis, structure-activity relationships and biological evaluation of 7-phenyl-pyrroloquinolinone 3-amide derivatives as potent antimitotic agents 316
AKR1C enzymes sustain therapy resistance in paediatric T-ALL 296
Targeting tubulin polymerization by novel 7-aryl-pyrroloquinolinones: Synthesis, biological activity and SARs 283
Glucocorticoid resistance is reverted by LCK inhibition in pediatric T-cell acute lymphoblastic leukemia 275
Ribociclib, a Cdk4/Cdk6 kinase inhibitor, enhances glucocorticoid sensitivity in B-acute lymphoblastic leukemia (B-All) 273
EB-3D a novel choline kinase inhibitor induces deregulation of the AMPK-mTOR pathway and apoptosis in leukemia T-cells 273
Design, Synthesis, and Biological Evaluation of 6-Substituted Thieno[3,2- d]pyrimidine Analogues as Dual Epidermal Growth Factor Receptor Kinase and Microtubule Inhibitors 273
Novel 3-Substituted 7-Phenylpyrrolo[3,2-f]quinolin-9(6H)-ones as Single Entities with Multitarget Antiproliferative Activity 272
Choline kinase alpha inhibition by EB-3D triggers cellular senescence, reduces tumor growth and metastatic dissemination in breast cancer 267
Study of the mechanism of action of new molecules endowed with antitumoral activity 265
Synthesis, in vitro and in vivo biological evaluation of substituted 3-(5-imidazo[2,1-b]thiazolylmethylene)-2-indolinones as new potent anticancer agents 250
Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo[b]furan derivatives as highly potent tubulin polymerization inhibitors 247
A novel copper(I) complex induces ER-stress-mediated apoptosis and sensitizes B-acute lymphoblastic leukemia cells to chemotherapeutic agents 245
A first-in-class Wiskott-Aldrich syndrome protein activator with anti-tumor activity in hematologic cancers 240
Developing novel classes of protein kinase CK1δ inhibitors by fusing [1,2,4]triazole with different bicyclic heteroaromatic systems 240
Multicomponent Approach to Bioactive Peptide-Ecdysteroid Conjugates: Creating Diversity at C6 by Means of the Ugi Reaction 226
A Multi-Omics Approach Reveals Enrichment in Metabolites Involved in the Regulation of the Glutathione Pathway in LIN28B-Dependent Cancer Cells 224
Vascular disrupting activity of combretastatin analogues 220
Lead optimization-hit expansion of new asymmetrical pyridinium/quinolinium compounds as choline kinase α1 inhibitors 219
Design, Synthesis and Biological Investigation of 2-Anilino Triazolopyrimidines as Tubulin Polymerization Inhibitors with Anticancer Activities 214
Identification of pyrrolo[3',4':3,4]cyclohepta[1,2-d][1,2]oxazoles as promising new candidates for the treatment of lymphomas 213
Design, synthesis and biological evaluation of novel vicinal diaryl-substituted 1H-Pyrazole analogues of combretastatin A-4 as highly potent tubulin polymerization inhibitors 213
Identification of Homoharringtonine as a potent inhibitor of glioblastoma cell proliferation and migration 212
Ecdysteroid Derivatives that Reverse P-Glycoprotein-Mediated Drug Resistance 209
Design, synthesis, in vitro, and in vivo anticancer and antiangiogenic activity of novel 3-arylaminobenzofuran derivatives targeting the colchicine site on tubulin 206
Cinnamic acid derivatives linked to arylpiperazines as novel potent inhibitors of tyrosinase activity and melanin synthesis 206
A facile synthesis of diaryl pyrroles led to the discovery of potent colchicine site antimitotic agents 202
Synthesis, DNA-binding and antiproliferative properties of diarylquinolizinium derivatives 199
Natural daucane esters induces apoptosis in leukaemic cells through ROS production 198
Synthesis and Biological Evaluation of Highly Active 7-Anilino Triazolopyrimidines as Potent Antimicrotubule Agents 197
Pyrrolo[2′,3′:3,4]cyclohepta[1,2- d][1,2]oxazoles, a New Class of Antimitotic Agents Active against Multiple Malignant Cell Types 197
TR-644 a novel potent tubulin binding agent induces impairment of endothelial cells function and inhibits angiogenesis 194
FOXO3a and posttranslational modifications mediate glucocorticoid sensitivity in B-ALL 194
Design, synthesis and biological evaluation of 3-substituted-2-oxindole hybrid derivatives as novel anticancer agents 193
Design, synthesis and biological evaluation of 2-alkoxycarbonyl-3-anilinoindoles as a new class of potent inhibitors of tubulin polymerization 193
Molecular and functional profiling of chemotolerant cells unveils nucleoside metabolism-dependent vulnerabilities in medulloblastoma 190
Complementary isonitrile-based multicomponent reactions for the synthesis of diversified cytotoxic hemiasterlin analogues 190
Histone Deacetylase Inhibitors Impair Glioblastoma Cell Motility and Proliferation 190
Surviving the hunger games: Metabolic reprogramming in medulloblastoma 187
Synthesis and in vitro evaluation of 3H-pyrrolo[3,2-f[quinolin-9-one derivatives that show potent and selective anti-leukemic activity 187
9-(4-Dimethylaminophenyl)benzo[b]quinolizinium: A Near-Infrared Fluorophore for the Multicolor Analysis of Proteins and Nucleic Acids in Living Cells 186
Hemiasterlin analogues incorporating an aromatic, and heterocyclic type C-terminus: design, synthesis and biological evaluation 184
Insight on [1,3]thiazolo[4,5-e]isoindoles as tubulin polymerization inhibitors 178
3-Aryl/Heteroaryl-5-amino-1-(3',4',5'-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of tubulin polymerization 174
Synthesis of 2H-Imidazo[2′,1':2,3] [1,3]thiazolo[4,5-e]isoindol-8-yl-phenylureas with promising therapeutic features for the treatment of acute myeloid leukemia (AML) with FLT3/ITD mutations 172
Design, synthesis and biological evaluation of 3,5-disubstituted 2-amino thiophene derivatives as a novel class of antitumor agents. 157
Design, synthesis, and biological investigation of selective human carbonic anhydrase II, IX, and XII inhibitors using 7-aryl/heteroaryl triazolopyrimidines bearing a sulfanilamide scaffold 156
Concise synthesis and biological evaluation of 2-Aryl-3-Anilinobenzo[b]thiophene derivatives as potent apoptosis-inducing agents 156
Synthesis, biological evaluation and molecular docking studies of trans-indole-3-acrylamide derivatives, a new class of tubulin polymerization inhibitors 154
Synthesis and Biological Evaluation of 2-Methyl-4,5-Disubstituted Oxazoles as a Novel Class of Highly Potent Antitubulin Agents 152
Concise Synthesis and Biological Evaluation of 2-Aroyl-5-Amino Benzo[ b ]thiophene Derivatives As a Novel Class of Potent Antimitotic Agents 150
Design, Synthesis, and Structure–Activity Relationships of Azolylmethylpyrroloquinolines as Nonsteroidal Aromatase Inhibitors 149
Synthesis and Biological Evaluation of 2-(Alkoxycarbonyl)-3-Anilinobenzo[b]thiophenes and Thieno[2,3-b]pyridines as New Potent Anticancer Agents. 147
Identification of novel indole derivatives acting as inhibitors of the Keap1-Nrf2 interaction 146
The Novel Antitubulin Agent TR-764 Strongly Reduces Tumor Vasculature and Inhibits HIF-1α Activation 146
Design and synthesis of potent in vitro and in vivo anticancer agents based on 1-(3',4',5'-trimethoxyphenyl)-2-Aryl-1H-imidazole 142
MG-2477, a new tubulin inhibitor, induces autophagy through inhibition of the Akt/mTOR pathway and delayed apoptosis in A549 cells. 141
Synthesis and Evaluation of 1,5-Disubstituted Tetrazoles as Rigid Analogues of Combretastatin A-4 with Potent Antiproliferative and Antitumor Activity 139
Synthesis and biological evaluation of 2-substituted-4-(3',4',5'-trimethoxyphenyl)-5-aryl thiazoles as anticancer agents. 139
Design and synthesis of azolylmethyl-pyrroloquinolines as potent and selective non steroidal CYP19 inhibitors 138
Derivati fenil-pirrolochinolinonici e loro uso 131
Design, synthesis and biological evaluation of 3,5-disubstituted 2-amino thiophene derivatives as a novel class of antitumor agents 130
Phytosterol and γ-Oryzanol Conjugates: Synthesis and Evaluation of their Antioxidant, Antiproliferative, and Anticholesterol Activities 129
Discovery of MG-2603 with in vitro potent antiproliferative activity by interfering with kinases and tubulin polymerisation 127
Design, synthesis, crystallization and biological evaluation of new symmetrical biscationic compounds as selective inhibitors of human Choline Kinase α1 (ChoKα1) 127
Synthesis and biological evaluation of 2-substituted-4-(3′,4′, 5′-trimethoxyphenyl)-5-aryl thiazoles as anticancer agents 115
Azolylmethyl-pyrroloquinolines as non steroidal aromatase inhibitors 111
Discovery of a novel class of anti-proliferative pyrrolo[3,2-f]quinolin-9-ones characterized by interfering with both PI3K-Akt-mTOR signalling and microtubule assembling 111
Design, synthesis and SARs of azolylmethyl-pyrroloquinolines as non steroidal aromatase inhibitors, NPCF7 109
Selective ratiometric detection of H2O2in water and in living cells with boronobenzo[b]quinolizinium derivatives 100
Discovery of MG-2603 with in vitro potent antiproliferative activity by interfering with kinases and tubulin polymerisation 82
Microwave‐Enhanced Synthesis of 2‐Styrylquinoline‐4‐Carboxamides With Promising Anti‐Lymphoma Activity 37
Design and Synthesis of 2-substituted [1,2,4]Triazolo[1,5-a]pyrimidines Tethered with Umbelliferone as Selective Carbonic Anhydrase IX and XII Inhibitors 33
TrkA activation sustains chemotherapy resistance in chemotolerant medulloblastoma cells 14
Totale 13.928
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Categoria #
all - tutte 40.137
article - articoli 37.133
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 435
selected - selezionate 0
volume - volumi 0
Totale 77.705
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022868 0 89 150 32 45 50 46 91 38 42 103 182
2022/2023563 108 19 5 72 77 82 3 45 87 21 39 5
2023/2024412 20 70 43 33 33 19 37 18 26 29 46 38
2024/20251.862 6 115 82 68 230 47 151 192 133 85 328 425
2025/20267.230 389 594 835 1.185 616 330 1.078 606 738 405 320 134
2026/2027314 243 71 0 0 0 0 0 0 0 0 0 0
Totale 13.928