BORTOLOZZI, ROBERTA
 Distribuzione geografica
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Continente #
NA - Nord America 3.960
AS - Asia 581
EU - Europa 437
SA - Sud America 2
OC - Oceania 1
Totale 4.981
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Nazione #
US - Stati Uniti d'America 3.949
CN - Cina 328
SG - Singapore 208
IT - Italia 167
FI - Finlandia 74
DE - Germania 61
GB - Regno Unito 32
FR - Francia 30
RU - Federazione Russa 23
VN - Vietnam 22
SE - Svezia 18
IN - India 17
UA - Ucraina 10
CA - Canada 9
NL - Olanda 8
IE - Irlanda 5
AT - Austria 2
ES - Italia 2
HK - Hong Kong 2
JO - Giordania 2
MX - Messico 2
RO - Romania 2
AZ - Azerbaigian 1
BR - Brasile 1
CH - Svizzera 1
CO - Colombia 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
PL - Polonia 1
TH - Thailandia 1
Totale 4.981
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Città #
Fairfield 696
Woodbridge 352
Houston 345
Ashburn 324
Seattle 289
Cambridge 269
Ann Arbor 231
Wilmington 225
Chandler 222
Singapore 173
Santa Clara 123
Boardman 90
San Diego 90
Beijing 66
Princeton 65
Medford 61
Des Moines 52
Roxbury 50
Padova 49
Helsinki 45
Nanjing 32
Shenyang 20
Dong Ket 19
Shanghai 15
Guangzhou 14
Hefei 13
London 13
Hebei 12
Jinan 12
Ogden 12
Milan 10
North York 9
Changsha 8
Kharkiv 8
Kunming 8
Pune 8
Grafing 7
Nanchang 7
Tianjin 7
Cagliari 6
Fuzhou 6
Jiaxing 6
Lappeenranta 6
New York 6
Rome 6
Falls Church 5
Jacksonville 5
Dublin 4
Haikou 4
Los Angeles 4
Chengdu 3
Hanoi 3
Portland 3
Qingdao 3
Redwood City 3
Rovigo 3
Zhengzhou 3
Amman 2
Bari 2
Birmingham 2
Bolgare 2
Brescia 2
Castenaso 2
Ciudad Nezahualcoyotl 2
Hangzhou 2
Hong Kong 2
Hyderabad 2
Kilburn 2
Lanzhou 2
L’Aquila 2
Mestre 2
Moncada 2
Ningbo 2
Prescot 2
Rockville 2
San Francisco 2
San Vito al Tagliamento 2
Sant'Anastasia 2
Taiyuan 2
Udine 2
Venice 2
Vienna 2
Wuhan 2
Acton 1
Alessandria 1
Aprilia 1
Auckland 1
Baku 1
Bitonto 1
Bogotá 1
Calvisano 1
Carol Stream 1
Chicago 1
Chiswick 1
Columbus 1
Cordenons 1
Costabissara 1
Dallas 1
Delhi 1
Falkenstein 1
Totale 4.199
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Nome #
Evaluating the effects of fluorine on biological properties and metabolic stability of some antitubulin 3-substituted 7-phenyl-pyrroloquinolinones 168
Synthesis, structure-activity relationships and biological evaluation of 7-phenyl-pyrroloquinolinone 3-amide derivatives as potent antimitotic agents 160
AKR1C enzymes sustain therapy resistance in paediatric T-ALL 144
Design, Synthesis, and Biological Evaluation of 6-Substituted Thieno[3,2- d]pyrimidine Analogues as Dual Epidermal Growth Factor Receptor Kinase and Microtubule Inhibitors 134
Choline kinase alpha inhibition by EB-3D triggers cellular senescence, reduces tumor growth and metastatic dissemination in breast cancer 130
Targeting tubulin polymerization by novel 7-aryl-pyrroloquinolinones: Synthesis, biological activity and SARs 129
EB-3D a novel choline kinase inhibitor induces deregulation of the AMPK-mTOR pathway and apoptosis in leukemia T-cells 128
Glucocorticoid resistance is reverted by LCK inhibition in pediatric T-cell acute lymphoblastic leukemia 127
Ribociclib, a Cdk4/Cdk6 kinase inhibitor, enhances glucocorticoid sensitivity in B-acute lymphoblastic leukemia (B-All) 120
A novel copper(I) complex induces ER-stress-mediated apoptosis and sensitizes B-acute lymphoblastic leukemia cells to chemotherapeutic agents 118
Design, synthesis, in vitro, and in vivo anticancer and antiangiogenic activity of novel 3-arylaminobenzofuran derivatives targeting the colchicine site on tubulin 116
Novel 3-Substituted 7-Phenylpyrrolo[3,2-f]quinolin-9(6H)-ones as Single Entities with Multitarget Antiproliferative Activity 112
Synthesis, in vitro and in vivo biological evaluation of substituted 3-(5-imidazo[2,1-b]thiazolylmethylene)-2-indolinones as new potent anticancer agents 109
3-Aryl/Heteroaryl-5-amino-1-(3',4',5'-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of tubulin polymerization 106
Lead optimization-hit expansion of new asymmetrical pyridinium/quinolinium compounds as choline kinase α1 inhibitors 105
TR-644 a novel potent tubulin binding agent induces impairment of endothelial cells function and inhibits angiogenesis 99
Synthesis and in vitro evaluation of 3H-pyrrolo[3,2-f[quinolin-9-one derivatives that show potent and selective anti-leukemic activity 95
Natural daucane esters induces apoptosis in leukaemic cells through ROS production 94
Design, synthesis and biological evaluation of 3,5-disubstituted 2-amino thiophene derivatives as a novel class of antitumor agents. 93
9-(4-Dimethylaminophenyl)benzo[b]quinolizinium: A Near-Infrared Fluorophore for the Multicolor Analysis of Proteins and Nucleic Acids in Living Cells 89
Identification of novel indole derivatives acting as inhibitors of the Keap1-Nrf2 interaction 89
Synthesis and biological evaluation of 2-substituted-4-(3',4',5'-trimethoxyphenyl)-5-aryl thiazoles as anticancer agents. 88
Vascular disrupting activity of combretastatin analogues 86
Design, synthesis and biological evaluation of 3-substituted-2-oxindole hybrid derivatives as novel anticancer agents 84
Hemiasterlin analogues incorporating an aromatic, and heterocyclic type C-terminus: design, synthesis and biological evaluation 83
Multicomponent Approach to Bioactive Peptide-Ecdysteroid Conjugates: Creating Diversity at C6 by Means of the Ugi Reaction 82
Study of the mechanism of action of new molecules endowed with antitumoral activity 81
MG-2477, a new tubulin inhibitor, induces autophagy through inhibition of the Akt/mTOR pathway and delayed apoptosis in A549 cells. 79
Synthesis, biological evaluation and molecular docking studies of trans-indole-3-acrylamide derivatives, a new class of tubulin polymerization inhibitors 76
Synthesis and Biological Evaluation of 2-(Alkoxycarbonyl)-3-Anilinobenzo[b]thiophenes and Thieno[2,3-b]pyridines as New Potent Anticancer Agents. 75
Complementary isonitrile-based multicomponent reactions for the synthesis of diversified cytotoxic hemiasterlin analogues 74
Pyrrolo[2′,3′:3,4]cyclohepta[1,2- d][1,2]oxazoles, a New Class of Antimitotic Agents Active against Multiple Malignant Cell Types 73
Synthesis and Evaluation of 1,5-Disubstituted Tetrazoles as Rigid Analogues of Combretastatin A-4 with Potent Antiproliferative and Antitumor Activity 70
Ecdysteroid Derivatives that Reverse P-Glycoprotein-Mediated Drug Resistance 70
Concise Synthesis and Biological Evaluation of 2-Aroyl-5-Amino Benzo[ b ]thiophene Derivatives As a Novel Class of Potent Antimitotic Agents 68
FOXO3a and posttranslational modifications mediate glucocorticoid sensitivity in B-ALL 67
Design and synthesis of potent in vitro and in vivo anticancer agents based on 1-(3',4',5'-trimethoxyphenyl)-2-Aryl-1H-imidazole 67
Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo[b]furan derivatives as highly potent tubulin polymerization inhibitors 66
Phytosterol and γ-Oryzanol Conjugates: Synthesis and Evaluation of their Antioxidant, Antiproliferative, and Anticholesterol Activities 65
Design, Synthesis, and Structure–Activity Relationships of Azolylmethylpyrroloquinolines as Nonsteroidal Aromatase Inhibitors 64
Synthesis and Biological Evaluation of 2-Methyl-4,5-Disubstituted Oxazoles as a Novel Class of Highly Potent Antitubulin Agents 64
Design, synthesis and biological evaluation of 3,5-disubstituted 2-amino thiophene derivatives as a novel class of antitumor agents 64
Design, synthesis and biological evaluation of novel vicinal diaryl-substituted 1H-Pyrazole analogues of combretastatin A-4 as highly potent tubulin polymerization inhibitors 63
Synthesis, DNA-binding and antiproliferative properties of diarylquinolizinium derivatives 62
Design, synthesis, crystallization and biological evaluation of new symmetrical biscationic compounds as selective inhibitors of human Choline Kinase α1 (ChoKα1) 58
The Novel Antitubulin Agent TR-764 Strongly Reduces Tumor Vasculature and Inhibits HIF-1α Activation 55
Design, synthesis and biological evaluation of 2-alkoxycarbonyl-3-anilinoindoles as a new class of potent inhibitors of tubulin polymerization 51
Developing novel classes of protein kinase CK1δ inhibitors by fusing [1,2,4]triazole with different bicyclic heteroaromatic systems 49
Insight on [1,3]thiazolo[4,5-e]isoindoles as tubulin polymerization inhibitors 48
Derivati fenil-pirrolochinolinonici e loro uso 47
Synthesis and biological evaluation of 2-substituted-4-(3′,4′, 5′-trimethoxyphenyl)-5-aryl thiazoles as anticancer agents 46
A facile synthesis of diaryl pyrroles led to the discovery of potent colchicine site antimitotic agents 45
Azolylmethyl-pyrroloquinolines as non steroidal aromatase inhibitors 44
Selective ratiometric detection of H2O2in water and in living cells with boronobenzo[b]quinolizinium derivatives 43
Design and synthesis of azolylmethyl-pyrroloquinolines as potent and selective non steroidal CYP19 inhibitors 43
Concise synthesis and biological evaluation of 2-Aryl-3-Anilinobenzo[b]thiophene derivatives as potent apoptosis-inducing agents 38
Cinnamic acid derivatives linked to arylpiperazines as novel potent inhibitors of tyrosinase activity and melanin synthesis 35
Discovery of a novel class of anti-proliferative pyrrolo[3,2-f]quinolin-9-ones characterized by interfering with both PI3K-Akt-mTOR signalling and microtubule assembling 33
Design, Synthesis and Biological Investigation of 2-Anilino Triazolopyrimidines as Tubulin Polymerization Inhibitors with Anticancer Activities 29
Design, synthesis and SARs of azolylmethyl-pyrroloquinolines as non steroidal aromatase inhibitors, NPCF7 28
Synthesis and Biological Evaluation of Highly Active 7-Anilino Triazolopyrimidines as Potent Antimicrotubule Agents 26
Histone Deacetylase Inhibitors Impair Glioblastoma Cell Motility and Proliferation 25
Identification of Homoharringtonine as a potent inhibitor of glioblastoma cell proliferation and migration 23
Discovery of MG-2603 with in vitro potent antiproliferative activity by interfering with kinases and tubulin polymerisation 23
Discovery of MG-2603 with in vitro potent antiproliferative activity by interfering with kinases and tubulin polymerisation 23
Identification of pyrrolo[3',4':3,4]cyclohepta[1,2-d][1,2]oxazoles as promising new candidates for the treatment of lymphomas 21
Synthesis of 2H-Imidazo[2′,1':2,3] [1,3]thiazolo[4,5-e]isoindol-8-yl-phenylureas with promising therapeutic features for the treatment of acute myeloid leukemia (AML) with FLT3/ITD mutations 20
Design, synthesis, and biological investigation of selective human carbonic anhydrase II, IX, and XII inhibitors using 7-aryl/heteroaryl triazolopyrimidines bearing a sulfanilamide scaffold 19
Surviving the hunger games: Metabolic reprogramming in medulloblastoma 18
A Multi-Omics Approach Reveals Enrichment in Metabolites Involved in the Regulation of the Glutathione Pathway in LIN28B-Dependent Cancer Cells 18
Molecular and functional profiling of chemotolerant cells unveils nucleoside metabolism-dependent vulnerabilities in medulloblastoma 14
A first-in-class Wiskott-Aldrich syndrome protein activator with anti-tumor activity in hematologic cancers 10
Totale 5.068
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Categoria #
all - tutte 21.288
article - articoli 19.968
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 194
selected - selezionate 0
volume - volumi 0
Totale 41.450
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020726 0 0 0 0 0 77 136 107 147 138 73 48
2020/2021877 42 70 26 54 18 32 98 61 134 140 103 99
2021/2022891 23 89 150 32 45 50 46 91 38 42 103 182
2022/2023563 108 19 5 72 77 82 3 45 87 21 39 5
2023/2024412 20 70 43 33 33 19 37 18 26 29 46 38
2024/2025546 6 115 82 68 230 45 0 0 0 0 0 0
Totale 5.068