BORTOLOZZI, ROBERTA
 Distribuzione geografica
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Continente #
NA - Nord America 7.267
AS - Asia 4.123
EU - Europa 1.872
SA - Sud America 632
AF - Africa 580
Continente sconosciuto - Info sul continente non disponibili 147
OC - Oceania 79
Totale 14.700
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Nazione #
US - Stati Uniti d'America 6.851
SG - Singapore 1.261
CN - Cina 884
IT - Italia 509
VN - Vietnam 506
HK - Hong Kong 498
BR - Brasile 386
DE - Germania 175
FI - Finlandia 168
BD - Bangladesh 139
FR - Francia 134
IN - India 115
PL - Polonia 112
GB - Regno Unito 94
CA - Canada 87
JP - Giappone 78
RU - Federazione Russa 77
NL - Olanda 71
IQ - Iraq 49
AR - Argentina 48
PK - Pakistan 48
SE - Svezia 45
TR - Turchia 45
JM - Giamaica 42
MX - Messico 38
SA - Arabia Saudita 36
BJ - Benin 35
ES - Italia 34
ID - Indonesia 34
UA - Ucraina 34
CO - Colombia 32
KR - Corea 32
PH - Filippine 31
ZA - Sudafrica 31
IE - Irlanda 30
EE - Estonia 28
TH - Thailandia 26
VE - Venezuela 26
CR - Costa Rica 25
MY - Malesia 25
KE - Kenya 24
AT - Austria 23
BY - Bielorussia 23
CL - Cile 23
ET - Etiopia 23
PY - Paraguay 23
EC - Ecuador 22
JO - Giordania 22
EG - Egitto 21
HN - Honduras 21
AZ - Azerbaigian 20
CH - Svizzera 20
CV - Capo Verde 20
PE - Perù 20
PS - Palestinian Territory 20
RO - Romania 20
AL - Albania 19
BO - Bolivia 19
GF - Guiana Francese 19
KG - Kirghizistan 19
MR - Mauritania 19
PR - Porto Rico 19
TT - Trinidad e Tobago 19
AO - Angola 18
GT - Guatemala 18
MU - Mauritius 18
MZ - Mozambico 18
NI - Nicaragua 18
TJ - Tagikistan 18
CW - ???statistics.table.value.countryCode.CW??? 17
MK - Macedonia 17
ML - Mali 17
SN - Senegal 17
TW - Taiwan 17
UZ - Uzbekistan 17
ZW - Zimbabwe 17
AU - Australia 16
CI - Costa d'Avorio 16
CM - Camerun 16
CZ - Repubblica Ceca 16
NC - Nuova Caledonia 16
BG - Bulgaria 15
DK - Danimarca 15
HU - Ungheria 15
LV - Lettonia 15
NZ - Nuova Zelanda 15
PT - Portogallo 15
SI - Slovenia 15
TN - Tunisia 15
TZ - Tanzania 15
AE - Emirati Arabi Uniti 14
BA - Bosnia-Erzegovina 14
GA - Gabon 14
GH - Ghana 14
IL - Israele 14
PF - Polinesia Francese 14
UG - Uganda 14
AF - Afghanistan, Repubblica islamica di 13
DO - Repubblica Dominicana 13
GP - Guadalupe 13
Totale 13.976
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Città #
Ashburn 950
Singapore 760
Fairfield 696
San Jose 676
Hong Kong 452
Houston 352
Woodbridge 352
Seattle 297
Cambridge 269
Ann Arbor 231
Wilmington 230
Chandler 222
Beijing 193
Santa Clara 175
Council Bluffs 164
Los Angeles 140
Washington 140
Ho Chi Minh City 130
Hanoi 117
Helsinki 93
Boardman 90
San Diego 90
Princeton 70
Bytom 66
Dallas 62
Medford 61
Lauterbourg 59
Padova 57
New York 56
Des Moines 55
Munich 55
Tokyo 53
Roxbury 50
Hefei 46
Chicago 39
Rome 37
Milan 36
Guangzhou 34
Orem 33
Cotonou 32
Nanjing 32
Da Nang 31
Turku 30
Warsaw 30
Buffalo 29
São Paulo 29
Montreal 27
Seoul 24
Kingston 23
Amman 22
Dublin 22
London 22
Nairobi 22
The Dalles 22
Haiphong 21
Tianjin 21
Baghdad 20
San José 20
Shenyang 20
Dong Ket 19
Lahore 19
Padua 19
Tallinn 19
Baku 18
Brooklyn 18
Frankfurt am Main 18
Managua 18
Naples 18
Shanghai 18
Denver 17
Dushanbe 17
Johannesburg 17
Luanda 17
Praia 17
Tashkent 17
Abidjan 16
Dakar 16
Harare 16
Lappeenranta 16
Maputo 16
Noumea 16
Phoenix 16
Toronto 16
Vienna 16
Bamako 15
Bishkek 15
Chennai 15
Minsk 15
Nouakchott 15
Addis Ababa 14
Dar es Salaam 14
Kampala 14
Stockholm 14
Accra 13
Atlanta 13
Jeddah 13
Jinan 13
Libreville 13
Papeete 13
Riga 13
Totale 8.839
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Nome #
Evaluating the effects of fluorine on biological properties and metabolic stability of some antitubulin 3-substituted 7-phenyl-pyrroloquinolinones 392
Synthesis, structure-activity relationships and biological evaluation of 7-phenyl-pyrroloquinolinone 3-amide derivatives as potent antimitotic agents 334
AKR1C enzymes sustain therapy resistance in paediatric T-ALL 307
Targeting tubulin polymerization by novel 7-aryl-pyrroloquinolinones: Synthesis, biological activity and SARs 295
Study of the mechanism of action of new molecules endowed with antitumoral activity 293
Design, Synthesis, and Biological Evaluation of 6-Substituted Thieno[3,2- d]pyrimidine Analogues as Dual Epidermal Growth Factor Receptor Kinase and Microtubule Inhibitors 284
Glucocorticoid resistance is reverted by LCK inhibition in pediatric T-cell acute lymphoblastic leukemia 284
Novel 3-Substituted 7-Phenylpyrrolo[3,2-f]quinolin-9(6H)-ones as Single Entities with Multitarget Antiproliferative Activity 281
Ribociclib, a Cdk4/Cdk6 kinase inhibitor, enhances glucocorticoid sensitivity in B-acute lymphoblastic leukemia (B-All) 281
EB-3D a novel choline kinase inhibitor induces deregulation of the AMPK-mTOR pathway and apoptosis in leukemia T-cells 281
Choline kinase alpha inhibition by EB-3D triggers cellular senescence, reduces tumor growth and metastatic dissemination in breast cancer 271
Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo[b]furan derivatives as highly potent tubulin polymerization inhibitors 264
Synthesis, in vitro and in vivo biological evaluation of substituted 3-(5-imidazo[2,1-b]thiazolylmethylene)-2-indolinones as new potent anticancer agents 263
A novel copper(I) complex induces ER-stress-mediated apoptosis and sensitizes B-acute lymphoblastic leukemia cells to chemotherapeutic agents 252
Developing novel classes of protein kinase CK1δ inhibitors by fusing [1,2,4]triazole with different bicyclic heteroaromatic systems 252
A first-in-class Wiskott-Aldrich syndrome protein activator with anti-tumor activity in hematologic cancers 243
A Multi-Omics Approach Reveals Enrichment in Metabolites Involved in the Regulation of the Glutathione Pathway in LIN28B-Dependent Cancer Cells 235
Vascular disrupting activity of combretastatin analogues 233
Multicomponent Approach to Bioactive Peptide-Ecdysteroid Conjugates: Creating Diversity at C6 by Means of the Ugi Reaction 233
Identification of Homoharringtonine as a potent inhibitor of glioblastoma cell proliferation and migration 231
Design, Synthesis and Biological Investigation of 2-Anilino Triazolopyrimidines as Tubulin Polymerization Inhibitors with Anticancer Activities 229
Design, synthesis and biological evaluation of novel vicinal diaryl-substituted 1H-Pyrazole analogues of combretastatin A-4 as highly potent tubulin polymerization inhibitors 228
Ecdysteroid Derivatives that Reverse P-Glycoprotein-Mediated Drug Resistance 225
Lead optimization-hit expansion of new asymmetrical pyridinium/quinolinium compounds as choline kinase α1 inhibitors 224
Identification of pyrrolo[3',4':3,4]cyclohepta[1,2-d][1,2]oxazoles as promising new candidates for the treatment of lymphomas 222
Cinnamic acid derivatives linked to arylpiperazines as novel potent inhibitors of tyrosinase activity and melanin synthesis 220
Design, synthesis, in vitro, and in vivo anticancer and antiangiogenic activity of novel 3-arylaminobenzofuran derivatives targeting the colchicine site on tubulin 218
A facile synthesis of diaryl pyrroles led to the discovery of potent colchicine site antimitotic agents 217
Synthesis, DNA-binding and antiproliferative properties of diarylquinolizinium derivatives 212
Synthesis and Biological Evaluation of Highly Active 7-Anilino Triazolopyrimidines as Potent Antimicrotubule Agents 209
Surviving the hunger games: Metabolic reprogramming in medulloblastoma 207
Design, synthesis and biological evaluation of 2-alkoxycarbonyl-3-anilinoindoles as a new class of potent inhibitors of tubulin polymerization 206
Pyrrolo[2′,3′:3,4]cyclohepta[1,2- d][1,2]oxazoles, a New Class of Antimitotic Agents Active against Multiple Malignant Cell Types 206
Natural daucane esters induces apoptosis in leukaemic cells through ROS production 205
Design, synthesis and biological evaluation of 3-substituted-2-oxindole hybrid derivatives as novel anticancer agents 204
Molecular and functional profiling of chemotolerant cells unveils nucleoside metabolism-dependent vulnerabilities in medulloblastoma 203
TR-644 a novel potent tubulin binding agent induces impairment of endothelial cells function and inhibits angiogenesis 200
Histone Deacetylase Inhibitors Impair Glioblastoma Cell Motility and Proliferation 200
FOXO3a and posttranslational modifications mediate glucocorticoid sensitivity in B-ALL 199
Hemiasterlin analogues incorporating an aromatic, and heterocyclic type C-terminus: design, synthesis and biological evaluation 197
Synthesis and in vitro evaluation of 3H-pyrrolo[3,2-f[quinolin-9-one derivatives that show potent and selective anti-leukemic activity 196
Complementary isonitrile-based multicomponent reactions for the synthesis of diversified cytotoxic hemiasterlin analogues 195
9-(4-Dimethylaminophenyl)benzo[b]quinolizinium: A Near-Infrared Fluorophore for the Multicolor Analysis of Proteins and Nucleic Acids in Living Cells 190
3-Aryl/Heteroaryl-5-amino-1-(3',4',5'-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of tubulin polymerization 186
Insight on [1,3]thiazolo[4,5-e]isoindoles as tubulin polymerization inhibitors 181
Synthesis of 2H-Imidazo[2′,1':2,3] [1,3]thiazolo[4,5-e]isoindol-8-yl-phenylureas with promising therapeutic features for the treatment of acute myeloid leukemia (AML) with FLT3/ITD mutations 181
Design, synthesis, and biological investigation of selective human carbonic anhydrase II, IX, and XII inhibitors using 7-aryl/heteroaryl triazolopyrimidines bearing a sulfanilamide scaffold 171
Concise synthesis and biological evaluation of 2-Aryl-3-Anilinobenzo[b]thiophene derivatives as potent apoptosis-inducing agents 167
Synthesis, biological evaluation and molecular docking studies of trans-indole-3-acrylamide derivatives, a new class of tubulin polymerization inhibitors 166
Design, Synthesis, and Structure–Activity Relationships of Azolylmethylpyrroloquinolines as Nonsteroidal Aromatase Inhibitors 162
Design, synthesis and biological evaluation of 3,5-disubstituted 2-amino thiophene derivatives as a novel class of antitumor agents. 161
Synthesis and Biological Evaluation of 2-Methyl-4,5-Disubstituted Oxazoles as a Novel Class of Highly Potent Antitubulin Agents 159
Synthesis and Biological Evaluation of 2-(Alkoxycarbonyl)-3-Anilinobenzo[b]thiophenes and Thieno[2,3-b]pyridines as New Potent Anticancer Agents. 156
Concise Synthesis and Biological Evaluation of 2-Aroyl-5-Amino Benzo[ b ]thiophene Derivatives As a Novel Class of Potent Antimitotic Agents 156
The Novel Antitubulin Agent TR-764 Strongly Reduces Tumor Vasculature and Inhibits HIF-1α Activation 151
Synthesis and biological evaluation of 2-substituted-4-(3',4',5'-trimethoxyphenyl)-5-aryl thiazoles as anticancer agents. 150
Identification of novel indole derivatives acting as inhibitors of the Keap1-Nrf2 interaction 150
Design and synthesis of potent in vitro and in vivo anticancer agents based on 1-(3',4',5'-trimethoxyphenyl)-2-Aryl-1H-imidazole 149
MG-2477, a new tubulin inhibitor, induces autophagy through inhibition of the Akt/mTOR pathway and delayed apoptosis in A549 cells. 146
Synthesis and Evaluation of 1,5-Disubstituted Tetrazoles as Rigid Analogues of Combretastatin A-4 with Potent Antiproliferative and Antitumor Activity 146
Design and synthesis of azolylmethyl-pyrroloquinolines as potent and selective non steroidal CYP19 inhibitors 146
Design, synthesis and biological evaluation of 3,5-disubstituted 2-amino thiophene derivatives as a novel class of antitumor agents 137
Derivati fenil-pirrolochinolinonici e loro uso 136
Design, synthesis, crystallization and biological evaluation of new symmetrical biscationic compounds as selective inhibitors of human Choline Kinase α1 (ChoKα1) 134
Phytosterol and γ-Oryzanol Conjugates: Synthesis and Evaluation of their Antioxidant, Antiproliferative, and Anticholesterol Activities 133
Discovery of MG-2603 with in vitro potent antiproliferative activity by interfering with kinases and tubulin polymerisation 133
Synthesis and biological evaluation of 2-substituted-4-(3′,4′, 5′-trimethoxyphenyl)-5-aryl thiazoles as anticancer agents 123
Azolylmethyl-pyrroloquinolines as non steroidal aromatase inhibitors 117
Design, synthesis and SARs of azolylmethyl-pyrroloquinolines as non steroidal aromatase inhibitors, NPCF7 117
Discovery of a novel class of anti-proliferative pyrrolo[3,2-f]quinolin-9-ones characterized by interfering with both PI3K-Akt-mTOR signalling and microtubule assembling 115
Selective ratiometric detection of H2O2in water and in living cells with boronobenzo[b]quinolizinium derivatives 105
Discovery of MG-2603 with in vitro potent antiproliferative activity by interfering with kinases and tubulin polymerisation 84
Microwave‐Enhanced Synthesis of 2‐Styrylquinoline‐4‐Carboxamides With Promising Anti‐Lymphoma Activity 52
Design and Synthesis of 2-substituted [1,2,4]Triazolo[1,5-a]pyrimidines Tethered with Umbelliferone as Selective Carbonic Anhydrase IX and XII Inhibitors 48
TrkA activation sustains chemotherapy resistance in chemotolerant medulloblastoma cells 27
NRF2 activation is required for chemotherapy resistance acquisition in medulloblastoma via metabolic and redox adaptation 21
A PTX3/TLR4 axis sustains SHH-Medulloblastoma growth and defines a new therapeutic vulnerability 13
Totale 14.700
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Categoria #
all - tutte 42.337
article - articoli 39.165
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 460
selected - selezionate 0
volume - volumi 0
Totale 81.962
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022629 0 0 0 32 45 50 46 91 38 42 103 182
2022/2023563 108 19 5 72 77 82 3 45 87 21 39 5
2023/2024412 20 70 43 33 33 19 37 18 26 29 46 38
2024/20251.862 6 115 82 68 230 47 151 192 133 85 328 425
2025/20267.230 389 594 835 1.185 616 330 1.078 606 738 405 320 134
2026/20271.086 243 255 262 326 0 0 0 0 0 0 0 0
Totale 14.700