PLOTEGHER, NICOLETTA
PLOTEGHER, NICOLETTA
Dipartimento di Biologia - DiBio
A β-Glucosyl Sterol Probe for in situ Fluorescent Labelling in Neuronal Cells to Investigate Neurodegenerative Diseases
2024 Borsato, Giuseppe; Carnio, Francesco; Lunardon, Sara; Moletta, Mattia; Pavan, Giulio; Terrin, Francesca; Scarso, Alessandro; Plotegher, Nicoletta; Fabris, Fabrizio
Alpha-synuclein pore forming activity upon membrane association
2012 Tosatto, Laura; Alberto O., Andrighetti; Plotegher, Nicoletta; Valeria, Antonini; Tessari, Isabella; Leonardo, Ricci; Bubacco, Luigi; Mauro Dalla, Serra
Biophysical groundwork as a hinge to unravel the biology of α-synuclein aggregation and toxicity.
2014 Plotegher, Nicoletta; Greggio, Elisa; Bisaglia, Marco; Bubacco, Luigi
Ceramides in Parkinson's Disease: From Recent Evidence to New Hypotheses
2019 Plotegher, Nicoletta; Bubacco, Luigi; Greggio, Elisa; Civiero, Laura
Comprehensive Structural and Thermodynamic Analysis of Prefibrillar WT α-Synuclein and Its G51D, E46K, and A53T Mutants by a Combination of Small-Angle X-ray Scattering and Variational Bayesian Weighting
2020 Moretti, Paolo; Mariani, Paolo; Ortore, Maria Grazia; Plotegher, Nicoletta; Bubacco, Luigi; Beltramini, Mariano; Spinozzi, Francesco
Crosstalk between Lysosomes and Mitochondria in Parkinson's Disease
2017 Plotegher, Nicoletta; Duchen, Michael R
Divergent Effects of G2019S and R1441C LRRK2 Mutations on LRRK2 and Rab10 Phosphorylations in Mouse Tissues
2020 Iannotta, Lucia; Biosa, Alice; Kluss, Jillian H; Tombesi, Giulia; Kaganovich, Alice; Cogo, Susanna; Plotegher, Nicoletta; Civiero, Laura; Lobbestael, Evy; Baekelandt, Veerle; Cookson, Mark R; Greggio, Elisa
DJ-1 promotes energy balance by regulating both mitochondrial and autophagic homeostasis
2023 De Lazzari, Federica; Agostini, Francesco; Plotegher, Nicoletta; Sandre, Michele; Greggio, Elisa; Megighian, Aram; Bubacco, Luigi; Sandrelli, Federica; Whitworth, Alexander J; Bisaglia, Marco
DOPAL derived alpha-synuclein oligomers impair synaptic vesicles physiological function
2017 Plotegher, Nicoletta; Berti, Giulia; Ferrari, E.; Tessari, Isabella; Zanetti, Manuela; Lunelli, L.; Greggio, Elisa; Bisaglia, Marco; Veronesi, M.; Girotto, Stefania; Dalla Serra, M.; Perego, C.; Casella, L.; Bubacco, Luigi
DOPAL initiates αSynuclein-dependent impaired proteostasis and degeneration of neuronal projections in Parkinson's disease
2023 Masato, Anna; Plotegher, Nicoletta; Terrin, Francesca; Sandre, Michele; Faustini, Gaia; Thor, Andrea; Adams, Stephen; Berti, Giulia; Cogo, Susanna; De Lazzari, Federica; Fontana, Camilla Maria; Martinez, Paul Anthony; Strong, Randy; Bandopadhyay, Rina; Bisaglia, Marco; Bellucci, Arianna; Greggio, Elisa; Dalla Valle, Luisa; Boassa, Daniela; Bubacco, Luigi
Excitotoxicity Revisited: Mitochondria on the Verge of a Nervous Breakdown
2021 Plotegher, Nicoletta; Filadi, Riccardo; Pizzo, Paola; Duchen, Michael R
High-Pressure-Driven Reversible Dissociation of alpha-Synuclein Fibrils Reveals Structural Hierarchy
2017 Piccirilli, Federica; Plotegher, Nicoletta; Ortore, Maria Grazia; Tessari, Isabella; Brucale, Marco; Spinozzi, Francesco; Beltramini, Mariano; Mariani, Paolo; Militello, Valeria; Lupi, Stefano; Perucchi, Andrea; Bubacco, Luigi
Impaired cellular bioenergetics caused by GBA1 depletion sensitizes neurons to calcium overload
2020 Plotegher, N.; Perocheau, D.; Ferrazza, R.; Massaro, G.; Bhosale, G.; Zambon, F.; Rahim, A. A.; Guella, G.; Waddington, S. N.; Szabadkai, G.; Duchen, M. R.
Impaired dopamine metabolism in Parkinson's disease pathogenesis
2019 Masato, A.; Plotegher, N.; Boassa, D.; Bubacco, L.
Inhibition of ceramide synthesis reduces α‐synuclein proteinopathy in a cellular model of parkinson’s disease
2021 Mingione, A.; Pivari, F.; Plotegher, N.; Cas, M. D.; Zulueta, A.; Bocci, T.; Trinchera, M.; Albi, E.; Maglione, V.; Caretti, A.; Bubacco, L.; Paroni, R.; Bottai, D.; Ghidoni, R.; Signorelli, P.
Leucine-rich repeat kinase 2 positively regulates inflammation and down-regulates NF-κB p50 signaling in cultured microglia cells
2015 Russo, Isabella; Berti, Giulia; Plotegher, Nicoletta; Bernardo, Greta; Filograna, Roberta; Bubacco, Luigi; Greggio, Elisa
Linking ROS Levels to Autophagy: The Key Role of AMPK
2023 Agostini, Francesco; Bisaglia, Marco; Plotegher, Nicoletta
LRRK2 deficiency impacts ceramide metabolism in brain
2016 Ferrazza, Ruggero; Cogo, Susanna; Melrose, Heather; Bubacco, Luigi; Greggio, Elisa; Guella, Graziano; Civiero, Laura; Plotegher, Nicoletta
LRRK2 kinase activity regulates GCase level and enzymatic activity differently depending on cell type in Parkinson's disease
2022 Kedariti, Maria; Frattini, Emanuele; Baden, Pascale; Cogo, Susanna; Civiero, Laura; Ziviani, Elena; Zilio, Gianluca; Bertoli, Federico; Aureli, Massimo; Kaganovich, Alice; Cookson, Mark R; Stefanis, Leonidas; Surface, Matthew; Deleidi, Michela; Di Fonzo, Alessio; Alcalay, Roy N; Rideout, Hardy; Greggio, Elisa; Plotegher, Nicoletta
LRRK2 phosphorylates pre-synaptic N-ethylmaleimide sensitive fusion (NSF) protein enhancing its ATPase activity and SNARE complex disassembling rate
2016 Belluzzi, Elisa; Gonnelli, Adriano; Cirnaru, Maria Daniela; Marte, Antonella; Plotegher, Nicoletta; Russo, Isabella; Civiero, Laura; Cogo, Susanna; Carrion, Maria Perèz; Franchin, Cinzia; Arrigoni, Giorgio; Beltramini, Mariano; Bubacco, Luigi; Onofri, Franco; Piccoli, Giovanni; Greggio, Elisa