ACQUASALIENTE, LAURA
 Distribuzione geografica
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Continente #
NA - Nord America 6.150
AS - Asia 3.919
EU - Europa 2.150
SA - Sud America 548
AF - Africa 509
Continente sconosciuto - Info sul continente non disponibili 138
OC - Oceania 36
Totale 13.450
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Nazione #
US - Stati Uniti d'America 5.801
SG - Singapore 1.172
IT - Italia 782
VN - Vietnam 757
CN - Cina 687
HK - Hong Kong 324
BR - Brasile 315
DE - Germania 230
BD - Bangladesh 173
FR - Francia 142
FI - Finlandia 127
IN - India 115
PL - Polonia 98
GB - Regno Unito 94
CA - Canada 85
NL - Olanda 80
JP - Giappone 71
RU - Federazione Russa 65
SE - Svezia 65
TR - Turchia 65
IQ - Iraq 60
IE - Irlanda 44
AR - Argentina 41
PH - Filippine 40
ES - Italia 38
ID - Indonesia 36
AT - Austria 34
KR - Corea 34
MX - Messico 34
SA - Arabia Saudita 33
ZA - Sudafrica 33
PK - Pakistan 32
PY - Paraguay 32
EC - Ecuador 30
CH - Svizzera 29
UA - Ucraina 28
CO - Colombia 27
VE - Venezuela 26
AE - Emirati Arabi Uniti 24
CI - Costa d'Avorio 24
CR - Costa Rica 21
JM - Giamaica 20
KZ - Kazakistan 20
TN - Tunisia 19
UY - Uruguay 19
AM - Armenia 18
TH - Thailandia 18
BO - Bolivia 17
IL - Israele 17
MY - Malesia 17
NO - Norvegia 17
SN - Senegal 17
TT - Trinidad e Tobago 17
UZ - Uzbekistan 17
AO - Angola 16
BE - Belgio 16
CL - Cile 16
PS - Palestinian Territory 16
PT - Portogallo 16
RW - Ruanda 16
SD - Sudan 16
AL - Albania 15
CU - Cuba 15
CW - ???statistics.table.value.countryCode.CW??? 15
GA - Gabon 15
GM - Gambi 15
GR - Grecia 15
GT - Guatemala 15
HN - Honduras 15
JO - Giordania 15
ML - Mali 15
MU - Mauritius 15
TJ - Tagikistan 15
AZ - Azerbaigian 14
BB - Barbados 14
BG - Bulgaria 14
BW - Botswana 14
DJ - Gibuti 14
EG - Egitto 14
GF - Guiana Francese 14
GH - Ghana 14
KE - Kenya 14
NP - Nepal 14
RO - Romania 14
GN - Guinea 13
IS - Islanda 13
KG - Kirghizistan 13
LC - Santa Lucia 13
LU - Lussemburgo 13
PA - Panama 13
AU - Australia 12
BY - Bielorussia 12
CZ - Repubblica Ceca 12
HU - Ungheria 12
MA - Marocco 12
MD - Moldavia 12
MG - Madagascar 12
MR - Mauritania 12
PR - Porto Rico 12
RS - Serbia 12
Totale 12.825
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Città #
Ashburn 820
San Jose 782
Singapore 738
Fairfield 454
Hong Kong 285
Ann Arbor 261
Woodbridge 251
Ho Chi Minh City 220
Chandler 207
Houston 199
Hanoi 193
Santa Clara 165
Seattle 163
Padova 160
Council Bluffs 152
Beijing 150
Cambridge 145
Wilmington 138
Los Angeles 110
Boardman 97
New York 82
Bytom 73
Milan 68
Helsinki 66
Lauterbourg 57
San Diego 57
Da Nang 55
Princeton 55
Munich 54
Tokyo 54
Medford 50
Des Moines 47
Dallas 41
Buffalo 40
Rome 38
São Paulo 38
Roxbury 36
Dublin 35
Franklin 35
Orem 35
The Dalles 35
Guangzhou 34
Chicago 33
Padua 32
Turku 29
Haiphong 27
Denver 25
Abidjan 24
Brooklyn 23
Montreal 23
Nanjing 23
Chennai 22
Hefei 22
Vienna 22
Boston 21
Amsterdam 20
Atlanta 20
Baghdad 20
Bologna 20
Toronto 20
Warsaw 20
Istanbul 19
Frankfurt am Main 18
London 18
Stockholm 18
Paris 17
Seoul 17
Bến Tre 16
Dakar 16
Jacksonville 16
Johannesburg 16
Washington 16
Jeddah 15
Libreville 15
Montevideo 15
Naples 15
San José 15
Tashkent 15
Bamako 14
Dushanbe 14
Havana 14
Kigali 14
Luanda 14
Phoenix 14
Poplar 14
Zurich 14
Accra 13
Biên Hòa 13
Bridgetown 13
Castries 13
Florence 13
Jakarta 13
Panama City 13
Rio de Janeiro 13
Venice 13
Vicenza 13
Antananarivo 12
Athens 12
Bishkek 12
Conakry 12
Totale 7.788
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Nome #
Endocrine Disruption of Vitamin D Activity by Perfluoro-Octanoic Acid (PFOA) 378
Endocrine disruption of androgenic activity by perfluoroalkyl substances: clinical and experimental evidence 356
Beta2-glycoprotein I selectively inhibits the procoagulant functions of thrombin 350
Coagulation protein factors: discovering novel interactions of thrombin 348
A MICU1 Splice Variant Confers High Sensitivity to the Mitochondrial Ca2+ Uptake Machinery of Skeletal Muscle 332
Perfluorooctanoic acid alters progesterone activity in human endometrial cells and induces reproductive alterations in young women 309
A conserved Neurite Outgrowth and Guidance motif with biomimetic potential in neuronal Cell Adhesion Molecules 302
Identifying conformational changes with site-directed spin labeling reveals that the GTPase domain of HydF is a molecular switch 290
Protein Engineering by Chemical Methods: Incorporation of Nonnatural Amino Acids as a Tool for Studying Protein Folding, Stability, and Function 290
Preliminary Discovery of Small Molecule Inhibitors of Epidermal Growth Factor Receptor (EGFR) That Bind to the Extracellular Domain 288
Noncoded amino acids in protein engineering: Structure-activity relationship studies of hirudin-thrombin interaction 274
Thrombin Inhibits the Anti-Myeloperoxidase and Ferroxidase Functions of Ceruloplasmin: Relevance in Rheumatoid Arthritis 274
Effects of point mutations in the binding pocket of the mouse major urinary protein MUP20 on ligand affinity and specificity 273
NOG-Derived Peptides Can Restore Neuritogenesis on a CRASH Syndrome Cell Model 270
Sperm cholesterol content modifies sperm function and trpv1‐mediated sperm migration 268
Non-canonical proteolytic activation of human prothrombin by subtilisin from Bacillus subtilis may shift the procoagulantâ anticoagulant equilibrium toward thrombosis 263
Lupus anticoagulant identifies two distinct groups of patients with different antibody patterns 263
Bacterial biofilms from Staphylococcus sp. trigger activation of coagulation: a possible link between infections and cardiovascular diseases 260
DOPAC as a modulator of α-Synuclein and E46K interactions with membrane: Insights into binding dynamics 250
Chemical Synthesis and Structure–Activity Relationship Studies of the Coagulation Factor Xa Inhibitor Tick Anticoagulant Peptide from the Hematophagous Parasite Ornithodoros moubata 245
Molecular Mapping of α -Thrombin( α T)/ β 2-Glycoprotein I(β2GpI) Interaction Reveals How β2GpI Affects α T Functions 234
The role of high molecular weight hyaluronic acid in mucoadhesion on an ocular surface model 233
Probing prothrombin structure by limited proteolysis 232
Loop Electrostatics Asymmetry Modulates the Preexisting Conformational Equilibrium in Thrombin 231
Onconase dimerization through 3D domain swapping: Structural investigations and increase in the apoptotic effect in cancer cells* 230
Circulating β2 glycoprotein I-IgG anti-β2 glycoprotein I immunocomplexes in patients with definite Antiphospholipid Syndrome. 229
Exogenous human α-Synuclein acts in vitro as a mild platelet antiaggregant inhibiting α-thrombin-induced platelet activation 227
Polyphenols as Potential Therapeutic Drugs in Neurodegeneration 220
Understanding thrombin allostery: Effect of exosite-1 and exosite-2 binders on enzyme recognition and catalysis 213
β2-Glycoprotein I Binds to Thrombin and Selectively Inhibits the Enzyme Procoagulant Functions 213
Novel Interactions of Thrombin 206
Bacterial biofilms produced by Staphylococcus sp. act as molecular scaffolds for the activation of blood coagulation 195
Interplay between conformational selection and zymogen activation 194
Identifying novel thrombin interactions: alpha-synuclein binds to thrombin exosites and inhibits thrombin-mediated platelet aggregation 190
Von Willebrand factor multimers and the relaxation response: A one-year study 184
The role of bacterial proteases in prothrombin activation. 183
Alternative proteolytic activation of human prothrombin by a bacterial serine protease 182
A novel genetically-encoded bicyclic peptide inhibitor of human urokinase-type plasminogen activator with better cross-reactivity toward the murine orthologue 179
N-terminal cleavage of cyclophilin D boosts its ability to bind F-ATP synthase 178
Structural Features and Toxicity of α-Synuclein Oligomers Grown in the Presence of DOPAC 177
Mapping specificity, cleavage entropy, allosteric changes and substrates of blood proteases in a high-throughput screen 176
Thrombin allostery: effect of exosite-1 and exosite-2 binders on the enzyme molecular recognition and catalysis 170
Aerosolized sulfated hyaluronan derivatives prolong the survival of K18 ACE2 mice infected with a lethal dose of SARS-CoV-2 169
From Haemadin to Haemanorm: Synthesis and Characterization of Full-length Haemadin from the leech Haemadipsa sylvestris and of a Novel Bivalent, Highly Potent Thrombin Inhibitor (Haemanorm) 160
The Role of Proteolysis in Amyloidosis 159
Identifying novel thrombin interactions: Alpha-synuclein binds to thrombin exosites and inhibits thrombin-mediated platelet aggregation 159
Synthesis and characterization of HAEMANORM-I: A novel highly potent bivalent thrombin inhibitor based on the structure of haemadin 154
Bacterial biofilms from Staphylococcus sp. trigger activation of coagulation: a possible link between infections and cardiovascular diseases 150
Staphylococcal biofilms: molecular scaffolds for the activation of blood coagulation 149
Beta 2 glycoprotein I selectively inhibits the procoagulant function of thrombin: a novel physiologic anticoagulant mechanism in haemostasis 147
Thrombin binds to human ceruloplasmin and proteolytically hinders its antioxidant activity 142
Identification of methionine sulfoxide at position 1606 of von Willebrand Factor (vWF) as a risk factor for thrombosis in patients with Antiphospholipid Syndrome (APS). 113
The impact of microstructure and extracellular matrix suspension on the proliferation of bone marrow-derived mesenchymal stem cells for osteochondral defect repair 111
The main protease (Mpro) from SARS-CoV-2 triggers plasma clotting in vitro by activating coagulation factors VII and FXII 109
Novel thrombin interactions: alpha-synuclein binds thrombin exosites and inhibits thrombin-mediated platelet aggregation 105
Thrombin binds human ceruloplasmin and proteolytically hinders its antioxidant activity: implications in the pathogenesis of rheumatoid arthritis 105
β2GpI binds to fibrinogen and alters fibrin generation and degradation 98
Thrombin binds human ceruloplasmin and proteolytically hinders its antioxidant activity: implication in the pathogenesis of rheumatoid arthritis 92
Thrombin proteolytically hinders the antioxidant activity of human ceruloplasmin: Implications in the pathogenesis of rheumatoid arthritis. 92
Characterization of a catalytically active thrombin precursor generated by non-canonical proteolytic activation 92
Human alpha-thrombin binds to and potently inhibits leukocyte myeloperoxidase: A novel Biochemical link between inflammation and coagulation 81
Importance of Prothrombin domains on the mechanism of activation. 74
Thrombin binds to human ceruloplasmin and proteolytically hinders its antioxidant activity 68
Native-MS as a suitable tool to select new scaffold for the inhibition of protein aggregation 64
An L-DOPA-PLP cyclic adduct exerts oxidative stress on ⍺-Synuclein 63
The aggregation kinetics of α-Synuclein is highly dependent on the protein dynamics in the native state 62
The native-state dynamics of α-Synuclein plays a crucial role in determining its aggregation kinetics 59
Targeting α-synuclein as a possible approach to combat Parkinson’s disease 57
Biophysical analysis of DOPAC-induced alterations in ⍺-Synuclein and E46K membrane binding dynamics 52
Light and pH effects on Ipilimumab conformational stability 51
Mapping of thrombin - Beta2-glycoprotein I interaction sites. 51
Towards the understanding of the effects of DOPAC on α-synuclein biophysical and biochemical properties. 48
Probing the role of α-synuclein extreme N-terminus in membrane interactions and aggregation by structural mass spectrometry. 16
Role of N-Terminus in α-Synuclein Conformations 15
The extreme N-terminus modulates α-synuclein membrane interactions, aggregation and conformational dynamics 13
Plasminogen Recruitment by Staphylococcus aureus SdrC Reveals a Tractable Antivirulence Target 11
Totale 13.450
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Categoria #
all - tutte 35.638
article - articoli 23.444
book - libri 580
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 59.662
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022591 0 101 34 48 28 30 53 56 30 13 46 152
2022/2023533 100 51 17 47 85 62 12 33 62 18 28 18
2023/2024564 18 58 58 42 50 75 34 96 26 42 34 31
2024/20251.744 19 110 96 116 190 68 119 156 121 89 275 385
2025/20267.289 336 449 708 992 621 285 1.423 627 829 441 351 227
2026/2027786 333 453 0 0 0 0 0 0 0 0 0 0
Totale 13.450