ACQUASALIENTE, LAURA
 Distribuzione geografica
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Continente #
NA - Nord America 2.940
EU - Europa 795
AS - Asia 457
SA - Sud America 2
AF - Africa 1
Continente sconosciuto - Info sul continente non disponibili 1
OC - Oceania 1
Totale 4.197
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Nazione #
US - Stati Uniti d'America 2.938
IT - Italia 417
CN - Cina 224
SG - Singapore 189
DE - Germania 117
FI - Finlandia 51
RU - Federazione Russa 46
FR - Francia 41
SE - Svezia 31
IE - Irlanda 24
GB - Regno Unito 23
NL - Olanda 17
KR - Corea 12
CH - Svizzera 10
HK - Hong Kong 9
IN - India 7
UA - Ucraina 6
IQ - Iraq 4
AT - Austria 3
BE - Belgio 3
JP - Giappone 3
PH - Filippine 3
PT - Portogallo 3
AL - Albania 2
BR - Brasile 2
CA - Canada 2
AU - Australia 1
BD - Bangladesh 1
EG - Egitto 1
EU - Europa 1
ID - Indonesia 1
IL - Israele 1
LT - Lituania 1
PS - Palestinian Territory 1
TH - Thailandia 1
TR - Turchia 1
Totale 4.197
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Città #
Fairfield 454
Ashburn 302
Ann Arbor 261
Woodbridge 250
Chandler 207
Houston 187
Padova 153
Seattle 152
Singapore 148
Cambridge 145
Wilmington 132
Boardman 96
Santa Clara 96
Princeton 55
San Diego 50
Medford 49
Des Moines 46
Beijing 43
Milan 37
Roxbury 36
Helsinki 28
Nanjing 22
Guangzhou 20
Dublin 19
Washington 13
Jacksonville 12
New York 11
Saint Louis 11
Seoul 11
Shenyang 10
Modena 9
Vicenza 9
Hong Kong 8
London 8
Rome 8
Zurich 8
Cagliari 7
Florence 6
Hebei 6
Ogden 6
Turin 6
Boston 5
Los Angeles 5
Munich 5
Nanchang 5
San Donà Di Piave 5
Treviso 5
Trieste 5
Zhengzhou 5
Changsha 4
Dallas 4
Fulham 4
Hefei 4
Naples 4
Norwalk 4
Paris 4
Pocapaglia 4
Torino 4
Verona 4
Agordo 3
Amsterdam 3
Ancona 3
Bologna 3
Brussels 3
Canelli 3
Erlangen 3
Frankfurt am Main 3
Haikou 3
Jiaxing 3
Kharkiv 3
Lappeenranta 3
Monza 3
Ningbo 3
Pescara 3
Pune 3
Salem 3
Taizhou 3
Tolentino 3
Venice 3
Ahmedabad 2
Alexandria 2
Aveiro 2
Berlin 2
Borås 2
Casale sul Sile 2
Cherasco 2
Columbus 2
Curtarolo 2
Davao City 2
Dearborn 2
Dongguan 2
Edinburgh 2
Fuzhou 2
Hangzhou 2
Hosur 2
Hounslow 2
Isernia 2
Jaboatao dos Guararapes 2
Jinan 2
Kunming 2
Totale 3.319
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Nome #
Endocrine disruption of androgenic activity by perfluoroalkyl substances: clinical and experimental evidence 171
Identifying conformational changes with site-directed spin labeling reveals that the GTPase domain of HydF is a molecular switch 169
Coagulation protein factors: discovering novel interactions of thrombin 162
Noncoded amino acids in protein engineering: Structure-activity relationship studies of hirudin-thrombin interaction 160
A MICU1 Splice Variant Confers High Sensitivity to the Mitochondrial Ca2+ Uptake Machinery of Skeletal Muscle 153
Effects of point mutations in the binding pocket of the mouse major urinary protein MUP20 on ligand affinity and specificity 141
Endocrine Disruption of Vitamin D Activity by Perfluoro-Octanoic Acid (PFOA) 135
Protein Engineering by Chemical Methods: Incorporation of Nonnatural Amino Acids as a Tool for Studying Protein Folding, Stability, and Function 131
Onconase dimerization through 3D domain swapping: Structural investigations and increase in the apoptotic effect in cancer cells* 131
Perfluorooctanoic acid alters progesterone activity in human endometrial cells and induces reproductive alterations in young women 122
Circulating β2 glycoprotein I-IgG anti-β2 glycoprotein I immunocomplexes in patients with definite Antiphospholipid Syndrome. 121
Probing prothrombin structure by limited proteolysis 119
Loop Electrostatics Asymmetry Modulates the Preexisting Conformational Equilibrium in Thrombin 118
Thrombin Inhibits the Anti-Myeloperoxidase and Ferroxidase Functions of Ceruloplasmin: Relevance in Rheumatoid Arthritis 111
Interplay between conformational selection and zymogen activation 110
Lupus anticoagulant identifies two distinct groups of patients with different antibody patterns 105
Identifying novel thrombin interactions: alpha-synuclein binds to thrombin exosites and inhibits thrombin-mediated platelet aggregation 94
Polyphenols as Potential Therapeutic Drugs in Neurodegeneration 93
β2-Glycoprotein I Binds to Thrombin and Selectively Inhibits the Enzyme Procoagulant Functions 88
Sperm cholesterol content modifies sperm function and trpv1‐mediated sperm migration 87
Molecular Mapping of α -Thrombin( α T)/ β 2-Glycoprotein I(β2GpI) Interaction Reveals How β2GpI Affects α T Functions 86
NOG-Derived Peptides Can Restore Neuritogenesis on a CRASH Syndrome Cell Model 80
Beta2-glycoprotein I selectively inhibits the procoagulant functions of thrombin 75
A conserved Neurite Outgrowth and Guidance motif with biomimetic potential in neuronal Cell Adhesion Molecules 74
Synthesis and characterization of HAEMANORM-I: A novel highly potent bivalent thrombin inhibitor based on the structure of haemadin 71
Thrombin allostery: effect of exosite-1 and exosite-2 binders on the enzyme molecular recognition and catalysis 70
Beta 2 glycoprotein I selectively inhibits the procoagulant function of thrombin: a novel physiologic anticoagulant mechanism in haemostasis 69
Thrombin binds to human ceruloplasmin and proteolytically hinders its antioxidant activity 68
Non-canonical proteolytic activation of human prothrombin by subtilisin from Bacillus subtilis may shift the procoagulantâ anticoagulant equilibrium toward thrombosis 65
Novel Interactions of Thrombin 64
Understanding thrombin allostery: Effect of exosite-1 and exosite-2 binders on enzyme recognition and catalysis 62
Von Willebrand factor multimers and the relaxation response: A one-year study 61
Alternative proteolytic activation of human prothrombin by a bacterial serine protease 56
The role of bacterial proteases in prothrombin activation. 52
Structural Features and Toxicity of α-Synuclein Oligomers Grown in the Presence of DOPAC 51
Identifying novel thrombin interactions: Alpha-synuclein binds to thrombin exosites and inhibits thrombin-mediated platelet aggregation 50
Mapping specificity, cleavage entropy, allosteric changes and substrates of blood proteases in a high-throughput screen 50
Thrombin binds human ceruloplasmin and proteolytically hinders its antioxidant activity: implications in the pathogenesis of rheumatoid arthritis 44
Thrombin binds human ceruloplasmin and proteolytically hinders its antioxidant activity: implication in the pathogenesis of rheumatoid arthritis 42
The role of high molecular weight hyaluronic acid in mucoadhesion on an ocular surface model 39
Exogenous human α-Synuclein acts in vitro as a mild platelet antiaggregant inhibiting α-thrombin-induced platelet activation 38
Novel thrombin interactions: alpha-synuclein binds thrombin exosites and inhibits thrombin-mediated platelet aggregation 38
Bacterial biofilms from Staphylococcus sp. trigger activation of coagulation: a possible link between infections and cardiovascular diseases 36
Preliminary Discovery of Small Molecule Inhibitors of Epidermal Growth Factor Receptor (EGFR) That Bind to the Extracellular Domain 35
Thrombin binds to human ceruloplasmin and proteolytically hinders its antioxidant activity 35
Bacterial biofilms produced by Staphylococcus sp. act as molecular scaffolds for the activation of blood coagulation 33
Identification of methionine sulfoxide at position 1606 of von Willebrand Factor (vWF) as a risk factor for thrombosis in patients with Antiphospholipid Syndrome (APS). 33
Aerosolized sulfated hyaluronan derivatives prolong the survival of K18 ACE2 mice infected with a lethal dose of SARS-CoV-2 32
Importance of Prothrombin domains on the mechanism of activation. 29
Characterization of a catalytically active thrombin precursor generated by non-canonical proteolytic activation 28
Human alpha-thrombin binds to and potently inhibits leukocyte myeloperoxidase: A novel Biochemical link between inflammation and coagulation 27
Staphylococcal biofilms: molecular scaffolds for the activation of blood coagulation 22
Bacterial biofilms from Staphylococcus sp. trigger activation of coagulation: a possible link between infections and cardiovascular diseases 20
β2GpI binds to fibrinogen and alters fibrin generation and degradation 20
A novel genetically-encoded bicyclic peptide inhibitor of human urokinase-type plasminogen activator with better cross-reactivity toward the murine orthologue 20
From Haemadin to Haemanorm: Synthesis and Characterization of Full-length Haemadin from the leech Haemadipsa sylvestris and of a Novel Bivalent, Highly Potent Thrombin Inhibitor (Haemanorm) 19
Thrombin proteolytically hinders the antioxidant activity of human ceruloplasmin: Implications in the pathogenesis of rheumatoid arthritis. 19
Mapping of thrombin - Beta2-glycoprotein I interaction sites. 17
Chemical Synthesis and Structure–Activity Relationship Studies of the Coagulation Factor Xa Inhibitor Tick Anticoagulant Peptide from the Hematophagous Parasite Ornithodoros moubata 13
The Role of Proteolysis in Amyloidosis 10
N-terminal cleavage of cyclophilin D boosts its ability to bind F-ATP synthase 5
Totale 4.279
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Categoria #
all - tutte 16.816
article - articoli 11.589
book - libri 331
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 28.736
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020321 0 0 0 0 0 0 74 63 66 74 32 12
2020/2021622 51 62 42 70 4 10 29 45 49 95 50 115
2021/2022602 11 101 34 48 28 30 53 56 30 13 46 152
2022/2023533 100 51 17 47 85 62 12 33 62 18 28 18
2023/2024564 18 58 58 42 50 75 34 96 26 42 34 31
2024/2025648 19 110 96 116 190 68 49 0 0 0 0 0
Totale 4.279