LOREGIAN, ARIANNA
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 8.496
EU - Europa 1.105
AS - Asia 1.002
SA - Sud America 19
AF - Africa 5
OC - Oceania 5
Totale 10.632
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 8.483
CN - Cina 595
SG - Singapore 335
IT - Italia 296
FI - Finlandia 175
DE - Germania 147
FR - Francia 106
SE - Svezia 96
UA - Ucraina 87
GB - Regno Unito 62
RU - Federazione Russa 57
IE - Irlanda 41
IN - India 37
VN - Vietnam 20
BR - Brasile 12
CA - Canada 10
ES - Italia 6
LU - Lussemburgo 5
NL - Olanda 5
SI - Slovenia 5
AU - Australia 4
JP - Giappone 4
RO - Romania 4
CL - Cile 3
GH - Ghana 3
KR - Corea 3
MX - Messico 3
PT - Portogallo 3
DK - Danimarca 2
HK - Hong Kong 2
RS - Serbia 2
UY - Uruguay 2
AT - Austria 1
BO - Bolivia 1
CH - Svizzera 1
CO - Colombia 1
GR - Grecia 1
IL - Israele 1
LA - Repubblica Popolare Democratica del Laos 1
LI - Liechtenstein 1
LV - Lettonia 1
MA - Marocco 1
MO - Macao, regione amministrativa speciale della Cina 1
MY - Malesia 1
NZ - Nuova Zelanda 1
PL - Polonia 1
TH - Thailandia 1
TW - Taiwan 1
ZA - Sudafrica 1
Totale 10.632
Salva come PNG Salva come JPEG
Città #
Fairfield 1.341
Woodbridge 863
Houston 736
Ashburn 655
Chandler 627
Ann Arbor 571
Seattle 511
Cambridge 492
Wilmington 463
Jacksonville 308
Singapore 281
Boardman 187
Princeton 175
Santa Clara 173
San Diego 139
Beijing 118
Helsinki 96
Roxbury 87
Guangzhou 85
Padova 77
Des Moines 75
Medford 60
Nanjing 59
Columbus 54
Shanghai 42
Dublin 41
Dearborn 31
Frankfurt am Main 30
Shenyang 24
Falls Church 22
London 20
Nanchang 20
Dong Ket 19
Milan 18
Norwalk 17
Pune 17
Berlin 16
Hebei 16
Redwood City 16
New York 14
Kharkiv 13
Washington 12
Changsha 11
Jiaxing 10
Hefei 9
Rome 9
Kunming 8
Tappahannock 8
Dallas 7
Ogden 7
Vicenza 7
Bengaluru 6
Camponogara 6
Chicago 6
Los Angeles 6
Aprilia 5
Borås 5
Buffalo 5
Crotone 5
Florence 5
Hanover 5
Jinan 5
Luxembourg 5
Moscow 5
Bergamo 4
Fuzhou 4
Irpin 4
Nürnberg 4
Paris 4
Perugia 4
Shenzhen 4
Tianjin 4
Abano Terme 3
Accra 3
Chiswick 3
Kilburn 3
Madrid 3
Oakville 3
Palermo 3
Pietro 3
San Francisco 3
Sydney 3
Taiyuan 3
Taizhou 3
Turin 3
Verona 3
Wuhan 3
Zhengzhou 3
Americana 2
Arce 2
Aversa 2
Belo Horizonte 2
Botucatu 2
Brasov 2
Chengdu 2
Copenhagen 2
Edinburgh 2
Falkenstein 2
Genoa 2
Gunzenhausen 2
Totale 8.870
Salva come PNG Salva come JPEG
Nome #
4,6-Diphenylpyridines as Promising Novel Anti-Influenza Agents Targeting the PA-PB1 Protein-Protein Interaction: Structure-Activity Relationships Exploration with the Aid of Molecular Modeling 201
The empirical antibiotic treatment of nosocomial spontaneous bacterial peritonitis: Results of a randomized, controlled clinical trial 169
Suppression of a SARS-CoV-2 outbreak in the Italian municipality of Vo' 168
A Broad anti-influenza hybrid small molecule that potently disrupts the interaction of polymerase acidic protein-basic protein 1 (PA-PB1) subunits 167
Antiviral strategies against influenza virus: towards new therapeutic approaches. 162
Strategies and methods in monitoring and targeting protein-protein interactions. 156
Synthesis and biological evaluation of a library of hybrid derivatives as inhibitors of influenza virus PA-PB1 interaction 155
Drug Repurposing for Viral Infectious Diseases: How Far Are We? 154
Drug Repurposing Approach Identifies Inhibitors of the Prototypic Viral Transcription Factor IE2 that Block Human Cytomegalovirus Replication 150
Role of homodimerization of human cytomegalovirus DNA polymerase accessory protein UL44 in origin-dependent DNA replication in cells. 146
Small molecule inhibitors of influenza A and B viruses that act by disrupting subunit interactions of the viral polymerase. 145
Early inhibitors of human cytomegalovirus: State-of-art and therapeutic perspectives. 139
Potent and broad-spectrum cycloheptathiophene-3-carboxamide compounds that target the PA-PB1 interaction of influenza virus RNA polymerase and possess a high barrier to drug resistance 139
4th European Seminars in Virology on Oncogenic and Oncolytic Viruses, in Bertinoro (Bologna), Italy 137
The isoquinoline alkaloid berberine inhibits human cytomegalovirus replication by interfering with the viral Immediate Early-2 (IE2) protein transactivating activity 137
Daclatasvir plasma level and resistance selection in HIV patients with hepatitis C virus cirrhosis treated with daclatasvir, sofosbuvir, and ribavirin 135
Simple determination of the HIV protease inhibitor atazanavir in human plasma by high-performance liquid chromatography with UV detection 134
Development of a simple HPLC-UV method for the determination of the hepatitis C virus inhibitor simeprevir in human plasma 133
HPV16 E6 and E7 upregulate the histone lysine demethylase KDM2B through the c-MYC/miR-146a-5p axys 130
Development and validation of a simple and robust HPLC method with UV detection for quantification of the hepatitis C virus inhibitor daclatasvir in human plasma 129
Design, synthesis, and evaluation of WC5 analogues as inhibitors of human cytomegalovirus Immediate-Early 2 protein, a promising target for anti-HCMV treatment. 128
Optimization of Small-Molecule Inhibitors of Influenza Virus Polymerase: From Thiophene-3-Carboxamide to Polyamido Scaffolds 128
Kinetics of Linezolid in Continuous Renal Replacement Therapy: An in Vitro Study 126
Identification and Characterization of an Extracellular Protease Activity Produced by the Marine Vibrio sp. 60. 126
Structural investigation of cycloheptathiophene-3-carboxamide derivatives targeting influenza virus polymerase assembly. 124
The 6-Aminoquinolone WC5 Inhibits Human Cytomegalovirus Replication at an Early Stage by Interfering with the Transactivating Activity of Viral Immediate-Early 2 Protein 122
Effect of neutral and acidic phospholipids on mitochondrial ATP synthase secondary structure. 121
A point mutation in a herpesvirus polymerase determines neuropathogenicity. 121
1,2,4-Triazolo[1,5-a]pyrimidines: Efficient one-step synthesis and functionalization as influenza polymerase PA-PB1 interaction disruptors 120
Construction of a fusion protein between B subunit of E. coli heat-labile enterotoxin and the C-terminus of herpes simplex virus-DNA polymerase. 119
The Sp1 transcription factor does not directly interact with the HIV-1 Tat protein 118
Efficient extracellular production of hybrid E. coli heat-labile enterotoxin B subunits in a marine vibrio. 117
Analysis of the Association of the Human Cytomegalovirus DNA Polymerase Subunit UL44 with the Viral DNA Replication Factor UL84 117
Optimization of N-Substituted Oseltamivir Derivatives as Potent Inhibitors of Group-1 and -2 Influenza A Neuraminidases, Including a Drug-Resistant Variant 117
Exploring the cycloheptathiophene-3-carboxamide scaffold to disrupt the interactions of the influenza polymerase subunits and obtain potent anti-influenza activity 117
The 6-Aminoquinolone WC5 Inhibits Different Functions of the Immediate-Early 2 (IE2) Protein of Human Cytomegalovirus That Are Essential for Viral Replication. 116
A site-selective hyaluronan-interferonα2a conjugate for the treatment of ovarian cancer 116
A quantitative LumiFluo assay to test inhibitory compounds blocking p53 degradation induced by human papillomavirus oncoprotein E6 in living cells 116
A sensitive and validated HPLC-UV method for the quantitative determination of the new antifungal drug isavuconazole in human plasma 116
Approaches for the generation of new anti-cytomegalovirus agents: identification of protein-protein interaction inhibitors and compounds against the HCMV IE2 protein. 115
Structure-Based Optimization of N-Substituted Oseltamivir Derivatives as Potent Anti-Influenza A Virus Agents with Significantly Improved Potency against Oseltamivir-Resistant N1-H274Y Variant 115
Effect of differential growth conditions on the dTTP pool size in herpes simplex virus-infected Vero cells. 111
The flexible loop of the human cytomegalovirus DNA polymerase processivity factor ppUL44 is required for efficient DNA binding and replication in cells 110
Analysis of the antigen specific T cell repertoires in HIV infection 110
Separation methods for acyclovir and related antiviral compounds 107
Measurement of ribavirin and evaluation of its stability in human plasma by high-performance liquid chromatography with UV detection 105
pH-Dependent Conformational Changes and Topology of Herpesvirus Translocating Peptide in a Membrane-Mimetic Enviroment. 104
A 6-Aminoquinolone Compound, WC5, with Potent and Selective Anti-Human Cytomegalovirus Activity 103
Effects of hepatitis C virus infection on the pharmacokinetics of ritonavir-boosted atazanavir in HIV-1-infected patients. 102
Binding parameters and thermodynamics of the interaction of the human cytomegalovirus DNA polymerase accessory protein, UL44, with DNA: implications for the processivity mechanism 102
Human cytomegalovirus DNA replication: antiviral targets and drugs. 101
Protein-protein interactions as targets for antiviral chemotherapy 101
Identification of new Th peptides from the cytomegalovirus protein pp65 to design a peptide library for generation of CD4 T cell lines for cellular immunoreconstitution 101
The Human Cytomegalovirus DNA Polymerase Processivity Factor UL44 is Modified by SUMO in a DNA-dependent manner 101
Repurposing the clinically approved calcium antagonist manidipine dihydrochloride as a new early inhibitor of human cytomegalovirus targeting the Immediate-Early 2 (IE2) protein 101
Specific inhibition of herpes virus replication by receptor-mediated entry of an antiviral peptide linked to Escherichia coli enterotoxin B subunit. 100
Quantitative analysis of ribonucleotide triphosphates in cell extracts by high-performance liquid chromatography and micellar electrokinetic capillary chromatography: a comparative study. 98
The catalytic subunit of herpes simplex virus type 1 DNA polymerase contains a nuclear localization signal in the UL42-binding region 96
Interaction of Sp1 transcription factor with HIV-1 Tatprotein: looking for cellular partners. 96
Inhibition of herpesvirus and influenza virus replication by blocking polymerase subunit interactions 94
A novel small-molecule inhibitor of the human papillomavirus E6-p53 interaction that reactivates p53 function and blocks cancer cells growth 93
EDTA protects E. coli heat-labile enterotoxin B subunit-based fusion proteins from proteolytic degradation during their production by Vibrio spp. 91
Efficient and regioselective one-step synthesis of 7-aryl-5-methyl- and 5-aryl-7-methyl-2-amino-[1,2,4]triazolo[1,5-a] pyrimidine derivatives 90
Drug Repurposing Campaigns for Human Cytomegalovirus Identify a Natural Compound Targeting the Immediate-Early 2 (IE2) Protein: A Comment on "The Natural Flavonoid Compound Deguelin Inhibits HCMV Lytic Replication within Fibroblasts" 90
How academic labs can approach the drug discovery process as a way to synergize with big pharma 89
Cloning, expression, and functional characterization of the equine herpesvirus 1 DNA polymerase and its accessory subunit. 89
Residues of human cytomegalovirus DNA polymerase catalytic subunit, UL54, that are necessary and sufficient for interaction with the accessory protein UL44. 88
Corrigendum to “Exploring the cycloheptathiophene-3-carboxamide scaffold to disrupt the interactions of the influenza polymerase subunits and obtain potent anti-influenza activity” [Eur. J. Med. Chem. 138 (2017) 128–139] (S0223523417304610) (10.1016/j.ejmech.2017.06.015)) 87
Unboosted fosamprenavir is associated with low drug exposure in hiv-infected patients with mild-moderate liver impairment for hcv-related cirrhosis. 85
The antifungal drug isavuconazole inhibits the replication of human cytomegalovirus (HCMV) and acts synergistically with anti-HCMV drugs 83
Disruption of protein-protein interactions: towards new targets for chemotherapy. 82
Multiple Phosphorylation Sites at the C-terminus Regulate Nuclear Import of HCMV DNA Polymerase Processivity Factor ppUL44. 82
Use of Vibrio spp. for expression of E. coli enterotoxin B subunit fusion proteins: purification and characterization of a chimera containing a C-terminal fragment of DNA polymerase from herpes virus type 1. 81
Quantitative analysis of ribonucleoside triphosphates (rNTPs) in human lymphoid cells by micellar electrokinetic capillary chromatography (MECC). 80
The Carboxy-Terminal Segment of the Human Cytomegalovirus DNA Polymerase Accessory Subunit UL44 Is Crucial for Viral Replication 79
Human Cytomegalovirus Inhibitor AL18 Also Possesses Activity against Influenza A and B Viruses. 79
Human CD4 T-cell repertoires specific for opportunistic pathogens. 77
Sulfated Derivatives of Escherichia coli K5 Polysaccharide are Potent Inhibitors of Human Cytomegalovirus. 77
The cytomegalovirus DNA polymerase subunit UL44 forms a C-clamp shaped dimer. 77
Peptide inhibition of HCMV DNA polymerase processivity 76
Regulated Transport into the Nucleus of Herpesviridae DNA Replication Core Proteins 73
Crystal structure of the B subunit of Escherichia coli heat-labile enterotoxin carrying peptides with anti-herpes simplex virus type 1 activity. 71
CD4 and CD8 epitope mapping of cytomegalovirus tegument protein pp65 for diagnostic, vaccinal and therapeutic purposes. 69
Synthesis and characterization of 1,2,4-triazolo[1,5-a]pyrimidine-2-carboxamide-based compounds targeting the PA-PB1 interface of influenza A virus polymerase 68
Discovery of highly potent and selective influenza virus neuraminidase inhibitors targeting 150-cavity 67
Selective anti-cytomegalovirus compounds discovered by screening for inhibitors of subunit interactions of the viral polymerase 66
Antiviral properties of new arylsulfone derivatives with activity against human betaherpesviruses 66
The Clinically Approved Antifungal Drug Posaconazole Inhibits Human Cytomegalovirus Replication 66
The dimeric form of hpv16 e6 is crucial to drive yap/taz upregulation through the targeting of hscrib 64
Disruption of the interactions between the subunits of herpesvirus DNA polymerases as a novel antiviral strategy. 61
Author Correction: Suppression of a SARS-CoV-2 outbreak in the Italian municipality of Vo’ (Nature, (2020), 584, 7821, (425-429), 10.1038/s41586-020-2488-1) 61
Specific residues in the connector loop of the human cytomegalovirus DNA polymerase accessory protein, UL44, are crucial for interaction with the UL54 catalytic subunit. 60
IN VITRO ANTIVIRAL ACTIVITY OF EPIGALLOCATECHIN GALLATE AGAINST RABIES VIRUS 56
Divide et impera: An In Silico Screening Targeting HCMV ppUL44 Processivity Factor Homodimerization Identifies Small Molecules Inhibiting Viral Replication 55
Crystal structure of the cytomegalovirus DNA polymerase subunit UL44 in complex with the C terminus from the catalytic subunit - Differences in structure and function relative to unliganded UL44 52
Indomethacin-based PROTACs as pan-coronavirus antiviral agents 51
Intranuclear delivery of an anti-HSV-1 peptide mediated by the B-subunit of cholera-like toxin. 50
Ethyl1,8-Naphthyridone-3-carboxylates Downregulate HPV-16 E6 and E7 Oncogenes Expression 44
A small molecule targeting the interaction between human papillomavirus E7 oncoprotein and cellular phosphatase PTPN14 exerts antitumoral activity in cervical cancer cells 43
Antiviral methods and compositions 43
Totale 10.305
Salva come PNG Salva come JPEG
Categoria #
all - tutte 40.905
article - articoli 39.026
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 242
patent - brevetti 457
selected - selezionate 0
volume - volumi 832
Totale 81.462
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.415 0 0 0 0 0 206 262 272 289 178 137 71
2020/20211.394 95 92 67 92 48 83 62 140 209 129 191 186
2021/20221.668 37 152 203 153 118 101 80 208 54 55 174 333
2022/20231.410 252 141 34 160 223 224 4 104 139 34 74 21
2023/2024930 24 116 145 56 83 74 109 54 18 107 63 81
2024/2025989 11 234 169 110 359 106 0 0 0 0 0 0
Totale 10.814