A 67-year-old man, with no history of neuromuscular disorders, came for evaluation of progressive weakness in his left arm. [18F]FDG PET-MRI highlights the presence of a moderate hypometabolism localized at the right precentral gyrus, suggesting a selective degeneration of neurons of the primary motor area. Final diagnosis was amyotrophic lateral sclerosis with additional features, consistent with ALS-plus syndrome.
Case 12: Atypical Upper Motor Neuron Disease
Cecchin D.;Soraru G.;
2025
Abstract
A 67-year-old man, with no history of neuromuscular disorders, came for evaluation of progressive weakness in his left arm. [18F]FDG PET-MRI highlights the presence of a moderate hypometabolism localized at the right precentral gyrus, suggesting a selective degeneration of neurons of the primary motor area. Final diagnosis was amyotrophic lateral sclerosis with additional features, consistent with ALS-plus syndrome.
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