The production of 47Sc for nuclear medicine applications is a complex challenge requiring innovative approaches to enhance yield and purity. In this study, we introduce a bilayer-target strategy using natural vanadium (natV) and enriched 50Ti irradiated by intermediate-energy proton beams. This novel methodology significantly advances the field, offering improved production efficiency without compromising radionuclidic purity, crucial for theranostic applications in precision medicine.
Bilayer target for efficient production of 47Sc from proton-induced irradiation
Barbaro, Francesca;De Dominicis, Lucia;
2025
Abstract
The production of 47Sc for nuclear medicine applications is a complex challenge requiring innovative approaches to enhance yield and purity. In this study, we introduce a bilayer-target strategy using natural vanadium (natV) and enriched 50Ti irradiated by intermediate-energy proton beams. This novel methodology significantly advances the field, offering improved production efficiency without compromising radionuclidic purity, crucial for theranostic applications in precision medicine.
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