This study investigates the prevalence of comorbidities in a non-small cell lung cancer (NSCLC) cohort and evaluates how comorbidities impact overall and cancer-specific mortality in patients. By examining a population-based cohort of 1674 NSCLC cases, distinct comorbidity patterns were identified. The results showed that even a single comorbidity significantly increased overall mortality risk. In contrast, only specific comorbidity patterns adversely affected cancer-specific survival. The findings underscore the importance of considering a patient’s comorbidity profile when determining prognosis and treatment plans for lung cancer. This research highlights the need for more personalized, comorbidity-oriented approaches in oncology care. Integrating comorbidity assessments could refine risk stratification, guide therapeutic decisions, and ultimately improve outcomes for NSCLC patients with complex health conditions.
Patterns of Comorbidities in Lung Cancer Patients and Survival
Buja, Alessandra;Rea, Federico;Rigon, Leonardo;Arcara, Giorgio;Pasello, Giulia;Guarneri, Valentina
2025
Abstract
This study investigates the prevalence of comorbidities in a non-small cell lung cancer (NSCLC) cohort and evaluates how comorbidities impact overall and cancer-specific mortality in patients. By examining a population-based cohort of 1674 NSCLC cases, distinct comorbidity patterns were identified. The results showed that even a single comorbidity significantly increased overall mortality risk. In contrast, only specific comorbidity patterns adversely affected cancer-specific survival. The findings underscore the importance of considering a patient’s comorbidity profile when determining prognosis and treatment plans for lung cancer. This research highlights the need for more personalized, comorbidity-oriented approaches in oncology care. Integrating comorbidity assessments could refine risk stratification, guide therapeutic decisions, and ultimately improve outcomes for NSCLC patients with complex health conditions.| File | Dimensione | Formato | |
|---|---|---|---|
|
cancers-17-01577.pdf
accesso aperto
Tipologia:
Published (Publisher's Version of Record)
Licenza:
Creative commons
Dimensione
536.69 kB
Formato
Adobe PDF
|
536.69 kB | Adobe PDF | Visualizza/Apri |
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.




