Atypical depression and emotion dysregulation: Clinical and psychopathological features

Background: Most atypical depression (AD) cases endorse prominent mood reactivity, anxiety, and interpersonal sensitivity, resembling some of the characteristics of emotional dysregulation (ED). The present study assesses the frequency and clinical features of different levels of ED in ADyes vs. non-AD(ADno) cases. Methods: The present cross-sectional study discriminated depressed outpatients screened with the Hamilton Depression rating scale with the Atypical Depression Supplement (SIGH-ADS), Symptom Checklist-90-Revised, Temperament Evaluation of Memphis, Pisa, Paris, and San Diego Auto-questionnaire, 110-item version, 36-item Difficulties in Emotion Regulation Scale (DERS), and Young Mania Rating Scale into people with high (EDhigh) vs. low (EDlow) for a broad range of clinical and psychopathological features. Descriptive statistics were followed by random forest analysis with “out-of-bag”[OOB] computation. Results: We included 326 patients (MDD = 204[62.60 %], BD-II = 105[32.20 %],...