A by-product of alcohol metabolism can damage the genome by crosslinking opposing DNA strands. The discovery of a safe mechanism that reverses such damage might open up avenues of research for drug discovery.A previously unknown mechanism for repairing DNA interstrand crosslinks.
A safe fix for alcohol-derived DNA damage
Gallina I.;
2020
Abstract
A by-product of alcohol metabolism can damage the genome by crosslinking opposing DNA strands. The discovery of a safe mechanism that reverses such damage might open up avenues of research for drug discovery.A previously unknown mechanism for repairing DNA interstrand crosslinks.
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