Relationships of affective temperament ratings to diagnosis and morbidity measures in major affective disorders

Background Ratings of affective temperament types show promise in helping to differentiate diagnostic groups among major affective disorders as well as to predict associations with important aspects of morbidity including suicidal risk. Methods The Temperament Evaluation of Memphis, Pisa, Paris, and San Diego auto-rating (TEMPS-A) questionnaire was completed by 858 unselected, consecutive, consenting adults diagnosed with a DSM-5 major affective disorder (173 bipolar-1 [BD-1]), 250 BD-2, 435 major depressive disorder [MDD]) to score for anxious (anx), cyclothymic (cyc), dysthymic (dys), hyperthymic (hyp), and irritable (irr) affective temperaments. We tested their associations with diagnosis and selected clinical factors, including diagnosis, depression scores, suicidal ideation or acts, substance abuse, episodes/year, and %-Time ill. Results Scores for cyc ranked: BD-2Â >Â BD-1Â >Â MDD; anx ranked: MDDÂ >Â BD-2Â >Â BD-1; irr was greater in BD than MDD; dys was greater in MDD than BD; ...