The complex human systemic circulation can be mimicked by exploiting in vitro simulators, giving the chance to replicate both physiological and pathological conditions. Specifically, in this work, it is considered the Pulse Duplicator (PD) in use at the Healing Research Laboratory, at the University of Padova, Italy, aimed at testing medical devices, accelerating innovation cycles, and rapidly exploring new effective practical solutions. Besides the opportunities of such a workbench, there are also some challenges, especially for issues that are related to the set-up of experiments, in order to guarantee their quality and repeatability. It goes without saying that the proper tuning of certain PD parameters is crucial. This paper shows how one can assist the system tuning procedure by leveraging some tools of dynamical systems.

Mimicking the Complex Human Circulatory System via a Custom Hydro-mechanical Pulse Duplicator

Manzoni, Eleonora
;
Rampazzo, Mirco;Maria Susin, Francesca
2022

Abstract

The complex human systemic circulation can be mimicked by exploiting in vitro simulators, giving the chance to replicate both physiological and pathological conditions. Specifically, in this work, it is considered the Pulse Duplicator (PD) in use at the Healing Research Laboratory, at the University of Padova, Italy, aimed at testing medical devices, accelerating innovation cycles, and rapidly exploring new effective practical solutions. Besides the opportunities of such a workbench, there are also some challenges, especially for issues that are related to the set-up of experiments, in order to guarantee their quality and repeatability. It goes without saying that the proper tuning of certain PD parameters is crucial. This paper shows how one can assist the system tuning procedure by leveraging some tools of dynamical systems.
2022
Proceedings of 2022 IEEE Workshop on Complexity in Engineering (COMPENG)
2022 IEEE Workshop on Complexity in Engineering, COMPENG 2022
9781728171241
File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11577/3471283
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 1
  • ???jsp.display-item.citation.isi??? ND
  • OpenAlex ND
social impact