Of magic bullets, multiple targets, and artificial intelligence. Are we all set to defeat cancer?

Personalized medicine applied to patients with complex diseases, like cancer, grants a better quality of life and longer survival. However, in most instances it is not curative, due to the onset of two main obstacles represented by undesired toxicity and/or drug resistance, which contribute to a different extent depending upon the inhibition mechanism. In this short commentary, we try to combine the idea of multi-targeting agents with an Artificial Intelligence platform to further improve patients’ treatment and allowing them to be cured or live essentially disease-free. (Figure presented)