Heterogeneity of management practices surrounding operable gallbladder cancer – results of the OMEGA-S international HPB surgical survey

Balakrishnan, A.; Jah, A.; Lesurtel, M.; Andersson, B.; Gibbs, P.; Harper, S. J. F.; Huguet, E. L.; Kosmoliaptsis, V.; Liau, S. S.; Praseedom, R. K.; Ramia, J. M.; Branes, A.; Lendoire, J.; Maithel, S.; Serrablo, A.; Abe, T.; Achalandabaso, M.; Adham, M.; Ahmet, A.; Al-Sarireh, B.; Albiol Quer, M.; Alconchel, F.; Alsammani, M.; Alseidi, A.; Anand, A.; Anselmo, A.; Antonakis, P.; Arabadzhieva, E.; de Aretxabala, X.; Aroori, S.; Ashley, S.; Ausania, F.; Banerjee, A.; Barabino, M.; Bartlett, A.; Bartsch, F.; Belli, A.; Beristain-Hernandez, J.; Berrevoet, F.; Bhatti, A. B. H.; Bhojwani, R.; Bjornsson, B.; Blaz, T.; Byrne, M.; Calvo, M. P.; Castellanos, J.; Castro, M. J.; Cavallucci, D.; Chang, D.; Christodoulis, G.; Ciacio, O.; Clavien, P. A.; Coker, A.; Conde-Rodriguez, M.; D'Amico, F. E.; D'Hondt, M.; Daams, F.; Dasari, B. V. M.; De Bellis, M.; de Meijer, V. E.; Dede, K.; Deiro, G.; Delgado, F. J. B.; Desai, G.; Di Gioia, A.; Di Martino, M.; Dixon, M.; Dorovinis, P.; Dumitrascu, T.; Ebata, T.; Eilard, M. S.; Erdmann, J.; Erkan, M.; Famularo, S.; Felli, E.; Fergadi, M.; Fernandez, G. B.; Fox, A.; Galodha, S.; Galun, D.; Ganandha, S.; Garcia, R. J. R.; Gemenetzis, G.; Giannone, F.; Gil, L.; Giorgakis, E.; Giovinazzo, F.; Giuffrida, M.; Giuliani, T.; Giuliante, F.; Gkekas, I.; Goel, M.; Goh, B. K.; Gomes, A.; Gruenberger, T.; Guevara, O.; Gulla, A.; Gupta, A.; Gupta, R.; Hakeem, A. R.; Hamid, H. K. S.; Heinrich, S.; Helton, S.; Hernandez-Alejandro, R.; Heumann, A.; Higuchi, R.; Hughes, D.; Inarejos, B. C.; Ivanecz, A.; Iwao, Y.; Iype, S.; Jaen, I.; Jie, M. J.; Jones, R.; Kacirek, K.; Kalayarasan, R.; Kaldarov, A.; Kaman, L.; Kanhere, H.; Kapoor, V. K.; Karanicolas, P.; Karayiannakis, A.; Kausar, A.; Khan, Z. A.; Kim, D. -S.; Klose, J.; Knowles, B.; Koh, P. S.; Kolodziejczyk, P.; Komorowski, A. L.; Koong, J. K.; Kozyrin, I.; Krishna, A.; Kron, P.; Kumar, N.; van Laarhoven, S.; Lakhey, P. J.; Lanari, J.; Laurenzi, A.; Leow, V. M.; Limbu, Y.; Liu, Y. -B.; Lob, S.; Lolis, E.; Lopez-Lopez, V.; Lozano, R. C.; Lundgren, L.; Machairas, N.; Magouliotis, D.; Mahamid, A.; Malde, D.; Malek, A.; Malik, H.; Malleo, G.; Marino, M. V.; Mayo, S. C.; Mazzola, M.; Memeo, R.; Menon, K.; Menzulin, R.; Mohan, R.; Morgul, H.; Moris, D.; Mulita, F.; Muttillo, E. M.; Nahm, C.; Nandasena, M.; Nashidengo, P. R.; Nickkholgh, A.; Nikov, A.; Noel, C.; O'Reilly, D.; O'Rourke, T.; Ohtsuka, M.; Omoshoro-Jones, J. A. O.; Pandanaboyana, S.; Pararas, N.; Patel, R.; Patkar, S.; Peng, J. S.; Perfecto, A.; Perinel, J.; Perivoliotis, K.; Perra, T.; Phan, M. T.; Piccolo, G.; Porcu, A.; Primavesi, F.; Primrose, J.; Pueyo-Periz, E.; Radenkovic, D.; Rammohan, A.; Rowcroft, A.; Sakata, J.; Saladino, E.; Schena, C. A.; Scholer, A.; Schwarz, C.; Serrano, P.; Silva, M.; Soreide, K.; Sparrelid, E.; Stattner, S.; Sturesson, C.; Sugiura, T.; Sumo, M.; Sutcliffe, R.; Teh, C.; Teo, J. Y.; Tepetes, K.; Thapa, P. B.; Thepbunchonchai, A.; Torres, J. B. P.; Torres, O. J. M.; Torzili, G.; Tovikkai, C.; Troncoso, A.; Tsoulfas, G.; Tuzuher, A.; Tzimas, G.; Umar, G. I.; Urbani, L.; Vanagas, T.; Varga, ADELINA IULIA; Velayutham, V.; Vigano, L.; Wakai, T.; Yang, Z.; Yip, V.; Zacharoulis, D.; Zakharov, E. A.; Zimmitti, G.

doi:10.1016/j.hpb.2022.06.014

Background: Gallbladder cancer (GBC) is an aggressive, uncommon malignancy, with variation in operative approaches adopted across centres and few large-scale studies to guide practice. We aimed to identify the extent of heterogeneity in GBC internationally to better inform the need for future multicentre studies. Methods: A 34-question online survey was disseminated to members of the European-African Hepatopancreatobiliary Association (EAHPBA), American Hepatopancreatobiliary Association (AHPBA) and Asia–Pacific Hepatopancreatobiliary Association (A-PHPBA) regarding practices around diagnostic workup, operative approach, utilization of neoadjuvant and adjuvant therapies and surveillance strategies. Results: Two hundred and three surgeons responded from 51 countries. High liver resection volume units (>50 resections/year) organised HPB multidisciplinary team discussion of GBCs more commonly than those with low volumes (p < 0.0001). Management practices exhibited areas of heterogeneity, ...