310-Helical peptides as spacers and templates for spectroscopic studies and organic syntheses

In this Ph.D. thesis rigid peptide 310-helical structures were applied for the design of rigid templates and spacers for different spectroscopic and photophysical studies as well as for organic syntheses. In particular, the influence of the macroscopic dipole of the peptide 310-helix on the electron transfer between the azulene and pyrene chromophoric moieties was investigated. Such structures were used also in FT-IR spectroscopy and exciton coupled CD method for the study of peculiarities of these tecnics. Finally, 310-helical peptides were served as templates for organic synthesis to enhance the helical stability of peptides.