Our research group has been exploring the synthetic versatility of 5,10,15,20 tetrakis(pentafluorophenyl)porphyrin (TPFFP) as a multipurpose scaffold to be efficiently and selectively derivatized by means of nucleophilic aromatic substitution reactions, devising a plethora of functional groups, generating libraries of photo-active compounds with biological interest. In this communication, an innovative functionalization of TPFFP, with different azabicyclic amidines will be reported. The structural characterization and the promising photophysical properties of the new compounds will be presented and discussed.
New Porphyrin Conjugates from azabicycloamidic for PDT Applications: from Synthesis to Photophysical properties
Giorgia Miolo
Conceptualization
;
2021
Abstract
Our research group has been exploring the synthetic versatility of 5,10,15,20 tetrakis(pentafluorophenyl)porphyrin (TPFFP) as a multipurpose scaffold to be efficiently and selectively derivatized by means of nucleophilic aromatic substitution reactions, devising a plethora of functional groups, generating libraries of photo-active compounds with biological interest. In this communication, an innovative functionalization of TPFFP, with different azabicyclic amidines will be reported. The structural characterization and the promising photophysical properties of the new compounds will be presented and discussed.
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