Cardiovascular diseases account for 40% of all deaths in the Western countries, and nearly two-thirds of the deaths occur suddenly. Effort is a trigger with a 3-fold risk in athletes compared with nonathletes, and sports disqualification is by itself lifesaving in people with underlying concealed cardiovascular diseases. Several causes of cardiac sudden death (SD) may be identified at postmortem. The spectrum of cardiovascular substrates is wide and includes congenital and acquired diseases. In up to 20% of cases, the heart is grossly and histologically normal at autopsy. The use of molecular techniques is nowadays mandatory in cases of unexplained cardiac SD. © 2013 Elsevier Inc.
Pathologic substrates of sudden cardiac death during sports
Basso C.Writing – Review & Editing
;Carturan E.Membro del Collaboration Group
;Pilichou K.Writing – Original Draft Preparation
;Rizzo S.Membro del Collaboration Group
;Corrado D.Membro del Collaboration Group
;Thiene G.
Funding Acquisition
2013
Abstract
Cardiovascular diseases account for 40% of all deaths in the Western countries, and nearly two-thirds of the deaths occur suddenly. Effort is a trigger with a 3-fold risk in athletes compared with nonathletes, and sports disqualification is by itself lifesaving in people with underlying concealed cardiovascular diseases. Several causes of cardiac sudden death (SD) may be identified at postmortem. The spectrum of cardiovascular substrates is wide and includes congenital and acquired diseases. In up to 20% of cases, the heart is grossly and histologically normal at autopsy. The use of molecular techniques is nowadays mandatory in cases of unexplained cardiac SD. © 2013 Elsevier Inc.Pubblicazioni consigliate
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