Double-blind randomized trial of t-DCS versus sham in Parkinson patients with mild cognitive impairment receiving cognitive training

The effect of computer-based cognitive training (CT) alone or in association with non-invasive brain stimulation (t-DCS) over the left dorsolateral prefrontal cortex (l-DLPFC) in Parkinson disease patients with Mild Cognitive Impairments (PD-MCI) is debated. The efficacy of acute t-DCS has been confirmed in AD and PD. By contrast, randomized t-DCS controlled trials in AD and PD have reported variable effects on cognition possibly due to protocol heterogeneity, The present study intends to verify the efficacy of t-DCS stimulation in a group of Psrkinson patients