Available diagnostics often fail to distinguish viral from bacterial causes of pediatric community-acquired pneumonia (pCAP). Metabolomics, which aims at characterizing diseases based on their metabolic signatures, has been applied to expand pathophysiological understanding of many diseases. In this exploratory study, we used the untargeted metabolomic analysis to shed new light on the etiology of pCAP.
New insights into pediatric community-acquired pneumonia gained from untargeted metabolomics: A preliminary study
Stocchero, Matteo;Giordano, Giuseppe;Pirillo, Paola;Zanconato, Stefania;Da Dalt, Liviana;Carraro, Silvia;Baraldi, Eugenio
2020
Abstract
Available diagnostics often fail to distinguish viral from bacterial causes of pediatric community-acquired pneumonia (pCAP). Metabolomics, which aims at characterizing diseases based on their metabolic signatures, has been applied to expand pathophysiological understanding of many diseases. In this exploratory study, we used the untargeted metabolomic analysis to shed new light on the etiology of pCAP.
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