In manufactured microfluidic channels, geometrical imperfections resulting from the manufacturing process are challenging in terms of reliability and functionality of the microfluidic device. In this work, a methodology for the geometrical and dimensional characterization of microfluidic channels using quantitative 3D optical microscopy is proposed. The methodology is based on a holistic approach including the identification of functionally relevant geometrical features and critical dimensions at design stage, as well as the related verification process at the manufacturing stage. At design stage, the critical geometrical characteristics are identified on the basis of their relation with the performance of the microfluidic device. Verification is based on a novel methodology in which measurement results collected by a surface topography measuring instrument are processed on the basis of concepts and procedures commonly applied to data generated by a coordinate measuring system.

A methodology for 3D geometrical characterisation of microfluidic channels using optical microscopy

Medeossi F.;Balcon M.;Carmignato S.;Savio E.;
2019

Abstract

In manufactured microfluidic channels, geometrical imperfections resulting from the manufacturing process are challenging in terms of reliability and functionality of the microfluidic device. In this work, a methodology for the geometrical and dimensional characterization of microfluidic channels using quantitative 3D optical microscopy is proposed. The methodology is based on a holistic approach including the identification of functionally relevant geometrical features and critical dimensions at design stage, as well as the related verification process at the manufacturing stage. At design stage, the critical geometrical characteristics are identified on the basis of their relation with the performance of the microfluidic device. Verification is based on a novel methodology in which measurement results collected by a surface topography measuring instrument are processed on the basis of concepts and procedures commonly applied to data generated by a coordinate measuring system.
File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11577/3317089
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 1
  • ???jsp.display-item.citation.isi??? 1
  • OpenAlex ND
social impact