Many molecular and functional details of single events in mitochondrial dynamics have been reported, but little is known about their coordination. A recent study describes how cellular Ca2+ signals, via remodelling the actin cytoskeleton, synchronise the formation of endoplasmic reticulum-mitochondria contacts with inner and outer mitochondrial membrane fission.
Organelles: The Emerging Signalling Chart of Mitochondrial Dynamics
Calì, Tito;Szabadkai, Gyorgy
2018
Abstract
Many molecular and functional details of single events in mitochondrial dynamics have been reported, but little is known about their coordination. A recent study describes how cellular Ca2+ signals, via remodelling the actin cytoskeleton, synchronise the formation of endoplasmic reticulum-mitochondria contacts with inner and outer mitochondrial membrane fission.
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