First- and second-line systemic treatments for metastatic and locally advanced soft tissue sarcomas in adults

This is the protocol for a review and there is no abstract. The objectives are as follows: To assess the effects of systemic therapy for the treatment of metastatic soft tissue sarcomas in a first-line metastatic setting. To assess the effects of systemic therapy for the treatment of metastatic soft tissue sarcomas in a second-line metastatic setting. To assess the effects of chemotherapy regimens adapted to specific sarcoma histologies. © 2016 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.