Ipatasertib plus paclitaxel versus placebo plus paclitaxel as first-line therapy for metastatic triple-negative breast cancer (LOTUS): a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial

Kim, Sung bae;Maslyar, Daniel J;Dent, Rebecca;Im, Seock ah;Espiã©, Marc;Blau, Sibel;Tan, Antoinette R;Isakoff, Steven J;Oliveira, Mafalda;Saura, Cristina;Wongchenko, Matthew J;Kapp, Amy V;Chan, Wai Y;Singel, Stina M;Baselga, Josã©;Kim, Sung bae;Lee, Keun Seok;Im, Seock ah;Espiã©, Marc;Wang, Hwei chung;Blau, Sibel;Dent, Rebecca;Tan, Antoinette;Sohn, Joo Hyuk;De Laurentiis, Michelino;Estevez, Laura Garcia;Huang, Chiun sheng;Romieu, Gilles;Velez, Michel;Villanueva, Rafael;CONTE, PIERFRANCO;Dakhil, Shaker;Debled, Marc;Martin, Antonio Gonzalez;Hurvitz, Sara;Kim, Jee Hyun;Levy, Christelle;Oliveira, Mafalda;Rovira, Pedro Sanchez;Seo, Jae Hong;Valero, Vicente;Vidal, Gregory;Wong, Andrea;Allison, Mary Ann K;Figlin, Robert;Chan, David;Chen, Shin cheh;Chen, Yen hsun;Cobleigh, Melody;De Braud, Filippo;Dirix, Luc;Hansen, Vincent;Bessard, Anne Hardy;Iannotti, Nicholas;Isakoff, Steven;Lawler, William;Montaã±o, Alvaro;Salkini, Mohamad;Seigel, Leonard

2017