Crohn's disease (CD) is a chronic idiopathic inflammatory condition potentially affecting any portion of the gastrointestinal tract, from mouth to anus, and characterized by a relapsing-remitting clinical behavior. In the past, treatment goals focused only on symptomatic control, but the discrepancy between clinical symptoms and active inflammation, and the introduction of more aggressive medical therapies (using biological and immunosuppressant agents) have made it necessary to reconsider our approach, focusing on clinical, laboratory and imaging data. A key issue in the management of patients with CD concerns how best to assess the disease's extent and inflammatory activity, detect potential complications, and measure treatment response.
MR enterography in pediatric and adult Crohn's disease: analyzing the apparent diffusion coefficient to assess active bowel wall inflammation
POMERRI, FABIO
2017
Abstract
Crohn's disease (CD) is a chronic idiopathic inflammatory condition potentially affecting any portion of the gastrointestinal tract, from mouth to anus, and characterized by a relapsing-remitting clinical behavior. In the past, treatment goals focused only on symptomatic control, but the discrepancy between clinical symptoms and active inflammation, and the introduction of more aggressive medical therapies (using biological and immunosuppressant agents) have made it necessary to reconsider our approach, focusing on clinical, laboratory and imaging data. A key issue in the management of patients with CD concerns how best to assess the disease's extent and inflammatory activity, detect potential complications, and measure treatment response.Pubblicazioni consigliate
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