Arrhythmogenic right ventricular cardiomyopathy dysplasia (ARVC/D) is a life-threatening entity, which has drawn the attention of the scientific community for the last 30 years since it is a significant cause of premature death. Young people, especially athletes, may die suddenly because of abrupt lethal cardiac arrhythmias, namely ventricular fibrillation, precipitated by exercise. The present chapter will deal with some aspects of the disease: history, terminology, biological background, pathology, and morphological criteria for diagnosis, endomyocardial biopsy, and recapitulation of the disease in transgenic mice.
Arrhythmogenic Cardiomyopathy: History and Pathology
THIENE, GAETANO;RIZZO, STEFANIA;PILICHOU, KALLIOPI;BASSO, CRISTINA
2016
Abstract
Arrhythmogenic right ventricular cardiomyopathy dysplasia (ARVC/D) is a life-threatening entity, which has drawn the attention of the scientific community for the last 30 years since it is a significant cause of premature death. Young people, especially athletes, may die suddenly because of abrupt lethal cardiac arrhythmias, namely ventricular fibrillation, precipitated by exercise. The present chapter will deal with some aspects of the disease: history, terminology, biological background, pathology, and morphological criteria for diagnosis, endomyocardial biopsy, and recapitulation of the disease in transgenic mice.
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