Enrofloxacin (E) is a synthetic fluoroquinolone antimicrobial agent, administered orally to turkeys for the treatment of respiratory and intestinal diseases. The aim of the study is to assess, in turkey, the extent of the in vitro hepatic biotransformation of Enrofloxacin (E) into Ciprofloxacin (C), its active metabolite, as the sum of E+C is the marker residue for edible tissues from treated turkey fixed by EU to minimize the risk for human health.
IN VITRO AND IN VIVO COMPARISON OF ENROFLOXACIN METABOLISM IN TURKEY.
MERLANTI, ROBERTA;LUCATELLO, LORENA;CAPOLONGO, FRANCESCA;MONTESISSA, CLARA
2014
Abstract
Enrofloxacin (E) is a synthetic fluoroquinolone antimicrobial agent, administered orally to turkeys for the treatment of respiratory and intestinal diseases. The aim of the study is to assess, in turkey, the extent of the in vitro hepatic biotransformation of Enrofloxacin (E) into Ciprofloxacin (C), its active metabolite, as the sum of E+C is the marker residue for edible tissues from treated turkey fixed by EU to minimize the risk for human health.
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