Transfer of process monitoring models between plants: Batch systems

tIn this paper, the problem of transferring a process monitoring model between different batch plants is addressed.By exploiting the data coming from a source plant similar to the target plant to which a batch production needs to betransferred, it is possible to transfer a process monitoring model to the target plant under the assumption that thesource plant and the target plant are driven by the same fundamental laws. Two transfer methodologies are proposed.The first one is based on multiway principal component analysis, and exploits the information of similar (“common”)variables that are measured both in the source plant and in the target plant. The second methodology is based on theuse of multiway joint-Y partial least-squares regression and exploits all the measured data, i.e. common variables aswell as variables that are measured only in one of the two plants. The effectiveness of the proposed methodologiesis demonstrated using a benchmark simulated fed-batch fermentation process for penicillin production.