The 32P-postlabelling assay and the micronucleus test have been used to evaluate spontaneous and induced levels of DNA damage in cultured mammalian cells (C6 and C2.8) following treatment with benzo[a]pyrene and [3H]anti-benzo[a]pyrene diolepoxide.
Metabolic activation of benzo(alpha)pyrene in fetal mouse hepatocyte lines: Induction of DNA adducts and micronuclei
CANOVA, SABRINA;VENIER, PAOLA;CELOTTI, LUCIA;
1997
Abstract
The 32P-postlabelling assay and the micronucleus test have been used to evaluate spontaneous and induced levels of DNA damage in cultured mammalian cells (C6 and C2.8) following treatment with benzo[a]pyrene and [3H]anti-benzo[a]pyrene diolepoxide.
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