This paper reports a detailed analysis on the time dependence of affinity constants. These studies were carried out by using some results obtained previously in a thermodynamic treatment of ligand-receptor interactions. The theoretical analysis here reported evidences that in a binding experiment which involves cooperative or non-cooperative phenomena, may be considered as equilibrium constants only those of sites which exhibit an equilibrium time lower than the measurement time
Polyamine binding to mitochondrial membrane: the time dependence of affinity constant
DI NOTO, VITO;DALLA VIA, LISA;TONINELLO, ANTONIO
1997
Abstract
This paper reports a detailed analysis on the time dependence of affinity constants. These studies were carried out by using some results obtained previously in a thermodynamic treatment of ligand-receptor interactions. The theoretical analysis here reported evidences that in a binding experiment which involves cooperative or non-cooperative phenomena, may be considered as equilibrium constants only those of sites which exhibit an equilibrium time lower than the measurement time
File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
