Palladium and platinum dithiocarbamato compexes containing mono- and diamines.

The [M(DMDT)X](n) (M=Pd or Pt; DMDT=Me2NCS2-; X=Cl or Br) species have been reacted with various amines (Py, pyridine; Pra, n-propylamine; Cba, cyclobutylamine; Dap, 1,3-diaminopropane; En, ethylenediamine) in dichloromethane with the aim of obtaining mixed complexes of various stoichiometries. Along with the neutral complexes M(DMDT)(L)X (L=Py, Pra or Cba), the ionic species IM(DMDT)(L,)IX, [M(DMDT)(En)]X and [M(DMDT)(Dap)]X have been isolated, which have been characterised by IR and proton NMR spectroscopy. Thermogravimetric data suggest a particular behaviour for the palladium-Pra and palladium-Cba derivatives, with formation of low-stoichiometry intermediates of formula Pd-2(DMDT)(2)AmX2. The behaviour of the prepared complexes in various solvents has been described on the basis of the proton NMR spectra. All complexes have been tested for in vitro cytostatic activity against KB cells.