The formation of complexes between iron(III) and two ligands of possible relevance to chelation therapy, 2-hydroxynicotinic acid and 3-hydroxypicolinic acid, in aqueous 0.6 m (Na)Cl at 25 °C, has been investigated by means of potentiometric titrations and UV measurements. In both cases several mononuclear complexes and their deprotonation products are formed.
New possible chelating agents of clinical interest for iron(III): 2-hydroxynicotinic acid and 3-hydroxypicolinic acid. A thermodynamic study
DI MARCO, VALERIO;TAPPARO, ANDREA;BOMBI, GIUSEPPE GIORGIO
2001
Abstract
The formation of complexes between iron(III) and two ligands of possible relevance to chelation therapy, 2-hydroxynicotinic acid and 3-hydroxypicolinic acid, in aqueous 0.6 m (Na)Cl at 25 °C, has been investigated by means of potentiometric titrations and UV measurements. In both cases several mononuclear complexes and their deprotonation products are formed.
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