The success of applying the tethering strategy in a synthetic molecular system strongly depends on the experimental conditions and is related to the strength of the noncovalent interaction and the competition between the 'captured' and unbound ligand for the recognition site.
Limitations of the "tethering" strategy for the detection of a weak noncovalent interaction
GASPARINI, GIULIO;PRINS, LEONARD JAN;SCRIMIN, PAOLO MARIA
2007
Abstract
The success of applying the tethering strategy in a synthetic molecular system strongly depends on the experimental conditions and is related to the strength of the noncovalent interaction and the competition between the 'captured' and unbound ligand for the recognition site.
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